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引用次数: 0
摘要
目的:通过不同的身体质量指数(BMI)来评价母亲身高过矮对妊娠期糖尿病的影响。方法:我们进行了这项基于人群的回顾性队列研究,包括加拿大纽芬兰和拉布拉多省东部卫生地区2012年1月1日至2019年12月31日出生的单胎妊娠个体。我们将产妇身高分为三组:75%(高身高)。我们进行了单变量和多变量回归分析(调整单变量分析中发现的潜在混杂因素),以确定矮身高是否是妊娠糖尿病的独立预测因子,并按BMI分类分层。结果:我们评估了15803例妊娠,其中1062例(6.7%)发生妊娠糖尿病。在所有BMI类别中,矮身高是妊娠糖尿病的独立预测因子(OR = 1.20, 95% CI 1.02-1.41, p = 0.031)。在分层分析中,在BMI正常的人群中,身高矮是妊娠糖尿病的独立预测因子(OR = 1.75, 95% CI 1.23-2.50, p = 0.002),但在BMI较高的人群中,身高矮不是独立预测因子。结论:母亲身高矮与妊娠期糖尿病的关系因BMI分级而异。在BMI正常的孕妇中,母亲身高过矮与妊娠期糖尿病的发生有关。
The impact of short maternal height on gestational diabetes.
Aims: To evaluate the impact of short maternal height on gestational diabetes, by different body mass index (BMI) classes.
Methods: We performed this population-based retrospective cohort study including individuals with singleton pregnancies delivering January 1st 2012 to December 31st 2019 in the Eastern Health region of the province of Newfoundland and Labrador, Canada. We divided maternal height into three groups: < 25% (short height), 25-75% (average height), and > 75% (tall height). We performed univariate and multivariate regression analyses (adjusting for potential confounders identified in univariate analyses) to determine if short height was an independent predictor of gestational diabetes, stratified by BMI class.
Results: We assessed 15,803 pregnancies, with 1062 (6.7%) experiencing gestational diabetes. Among all BMI categories combined, short height was an independent predictor of gestational diabetes (OR = 1.20, 95% CI 1.02-1.41, p = 0.031). In stratified analyses, short height was an independent predictor of gestational diabetes among those with a normal BMI (OR = 1.75, 95% CI 1.23-2.50, p = 0.002) but not an independent predictor in higher BMI classes.
Conclusions: The association between short maternal height and gestational diabetes varies by BMI class. Among those with a normal BMI, short maternal height is associated with the development of gestational diabetes.
期刊介绍:
Acta Diabetologica is a journal that publishes reports of experimental and clinical research on diabetes mellitus and related metabolic diseases. Original contributions on biochemical, physiological, pathophysiological and clinical aspects of research on diabetes and metabolic diseases are welcome. Reports are published in the form of original articles, short communications and letters to the editor. Invited reviews and editorials are also published. A Methodology forum, which publishes contributions on methodological aspects of diabetes in vivo and in vitro, is also available. The Editor-in-chief will be pleased to consider articles describing new techniques (e.g., new transplantation methods, metabolic models), of innovative importance in the field of diabetes/metabolism. Finally, workshop reports are also welcome in Acta Diabetologica.