瓦里安halcyon机器上前列腺和淋巴结体积的准直角选择。

IF 1.1 4区 医学 Q4 ONCOLOGY
Laura E O'Connor, Marissa R Pringle, Aubrey Buskerud, Nishele Lenards, Ashley Hunzeker, Matt Tobler
{"title":"瓦里安halcyon机器上前列腺和淋巴结体积的准直角选择。","authors":"Laura E O'Connor, Marissa R Pringle, Aubrey Buskerud, Nishele Lenards, Ashley Hunzeker, Matt Tobler","doi":"10.1016/j.meddos.2025.05.005","DOIUrl":null,"url":null,"abstract":"<p><p>Volumetric modulated arc therapy (VMAT), in conjunction with the split-jaw technique, has been widely used on TrueBeam linear accelerators to enhance dose conformity and mitigate the physical limitations of multileaf collimators (MLCs) when treating large, complex volumes. A new linear accelerator from Varian called the Halcyon does not have jaws and poses challenges in treating such volumes due to its unique MLC configuration. The goal of this study was to determine collimator angles effective in sparing organs at risk (OAR) and improving plan conformity for prostate and pelvic lymph node volumes exceeding 20 cm in length. Two VMAT plans (Plan A and B) were created. Plan A utilized departmental-standard collimator angles of 5°, 355°, 85°, and 90°, whereas Plan B was based on the work of Cozzi et al. and used collimator angles 20°, 45°, 340° and 90°. It was hypothesized that Plan A would reduce the volume of rectum and bladder receiving 40 Gy (V40) and volume of small bowel receiving 15 Gy (V15) by > 5% and achieve a conformity index closer to 1.0. Fourteen patients were retrospectively analyzed, and the 2plans were compared. The results showed no statistically significant differences in OAR sparing or conformity between the plans. Although researchers offered valuable insights into collimator angle selection for complex volumes on the Halcyon, future studies with larger sample sizes or other collimator angles may help refine treatment planning strategies.</p>","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Collimator angle selection for prostate and lymph node volumes on the Varian halcyon machine.\",\"authors\":\"Laura E O'Connor, Marissa R Pringle, Aubrey Buskerud, Nishele Lenards, Ashley Hunzeker, Matt Tobler\",\"doi\":\"10.1016/j.meddos.2025.05.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Volumetric modulated arc therapy (VMAT), in conjunction with the split-jaw technique, has been widely used on TrueBeam linear accelerators to enhance dose conformity and mitigate the physical limitations of multileaf collimators (MLCs) when treating large, complex volumes. A new linear accelerator from Varian called the Halcyon does not have jaws and poses challenges in treating such volumes due to its unique MLC configuration. The goal of this study was to determine collimator angles effective in sparing organs at risk (OAR) and improving plan conformity for prostate and pelvic lymph node volumes exceeding 20 cm in length. Two VMAT plans (Plan A and B) were created. Plan A utilized departmental-standard collimator angles of 5°, 355°, 85°, and 90°, whereas Plan B was based on the work of Cozzi et al. and used collimator angles 20°, 45°, 340° and 90°. It was hypothesized that Plan A would reduce the volume of rectum and bladder receiving 40 Gy (V40) and volume of small bowel receiving 15 Gy (V15) by > 5% and achieve a conformity index closer to 1.0. Fourteen patients were retrospectively analyzed, and the 2plans were compared. The results showed no statistically significant differences in OAR sparing or conformity between the plans. Although researchers offered valuable insights into collimator angle selection for complex volumes on the Halcyon, future studies with larger sample sizes or other collimator angles may help refine treatment planning strategies.</p>\",\"PeriodicalId\":49837,\"journal\":{\"name\":\"Medical Dosimetry\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Dosimetry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.meddos.2025.05.005\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Dosimetry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.meddos.2025.05.005","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

体积调制电弧治疗(VMAT),结合裂颌技术,已广泛应用于TrueBeam线性加速器,以提高剂量一致性,减轻多叶准直器(MLCs)在治疗大、复杂体积时的物理限制。瓦里安的新型直线加速器Halcyon没有颚,由于其独特的MLC结构,在处理如此大的体积时面临挑战。本研究的目的是确定准直角度有效地保留危险器官(OAR),并提高前列腺和盆腔淋巴结体积超过20cm的计划一致性。创建了两个VMAT计划(A计划和B计划)。方案A采用了部门标准的5°、355°、85°和90°的准直角,方案B基于Cozzi等人的工作,采用了20°、45°、340°和90°的准直角。假设A方案可使接受40 Gy (V40)的直肠和膀胱体积以及接受15 Gy (V15)的小肠体积减少b> %,达到接近1.0的符合指数。回顾性分析14例患者,并对两种方案进行比较。结果显示,两种方案在OAR保留或一致性方面没有统计学上的显著差异。尽管研究人员对Halcyon上复杂体积的准直器角度选择提供了有价值的见解,但未来更大样本量或其他准直器角度的研究可能有助于完善治疗计划策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Collimator angle selection for prostate and lymph node volumes on the Varian halcyon machine.

Volumetric modulated arc therapy (VMAT), in conjunction with the split-jaw technique, has been widely used on TrueBeam linear accelerators to enhance dose conformity and mitigate the physical limitations of multileaf collimators (MLCs) when treating large, complex volumes. A new linear accelerator from Varian called the Halcyon does not have jaws and poses challenges in treating such volumes due to its unique MLC configuration. The goal of this study was to determine collimator angles effective in sparing organs at risk (OAR) and improving plan conformity for prostate and pelvic lymph node volumes exceeding 20 cm in length. Two VMAT plans (Plan A and B) were created. Plan A utilized departmental-standard collimator angles of 5°, 355°, 85°, and 90°, whereas Plan B was based on the work of Cozzi et al. and used collimator angles 20°, 45°, 340° and 90°. It was hypothesized that Plan A would reduce the volume of rectum and bladder receiving 40 Gy (V40) and volume of small bowel receiving 15 Gy (V15) by > 5% and achieve a conformity index closer to 1.0. Fourteen patients were retrospectively analyzed, and the 2plans were compared. The results showed no statistically significant differences in OAR sparing or conformity between the plans. Although researchers offered valuable insights into collimator angle selection for complex volumes on the Halcyon, future studies with larger sample sizes or other collimator angles may help refine treatment planning strategies.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Medical Dosimetry
Medical Dosimetry 医学-核医学
CiteScore
2.40
自引率
0.00%
发文量
51
审稿时长
34 days
期刊介绍: Medical Dosimetry, the official journal of the American Association of Medical Dosimetrists, is the key source of information on new developments for the medical dosimetrist. Practical and comprehensive in coverage, the journal features original contributions and review articles by medical dosimetrists, oncologists, physicists, and radiation therapy technologists on clinical applications and techniques of external beam, interstitial, intracavitary and intraluminal irradiation in cancer management. Articles dealing primarily with physics will be reviewed by a specially appointed team of experts in the field.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信