创伤患者急诊开胸术后生存的临床决定因素:来自一级创伤中心的8年经验

IF 1.9 4区 医学 Q2 ORTHOPEDICS
Abhinav Kumar, Ramesh Vaidyanathan, Pratyusha Priyadarshini, Dinesh Bagaria, Narendra Choudhary, Junaid Alam, Sushma Sagar, Amit Gupta, Biplab Mishra, Mahroof Khan, Subodh Kumar
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引用次数: 0

摘要

目的:急诊开胸术(ET)是在危重患者紧急复苏过程中实施的一种挽救生命的手术。在引进这么多年后,围绕这种侵入性和消耗资源的手术的争议仍然挥之不去。ET可以作为创伤中心效率的几个指标之一,并提供有关创伤系统整体准备,资源和培训的信息。我们的目标是研究改善预后的临床决定因素,并回顾我们过去8年的ET经验。方法:2014年1月至2021年12月在我院接受ET治疗的所有患者纳入回顾性研究。不知道骤停时间或数据不完整的患者被排除在外。此外,患者固定,瞳孔扩大到达有明显钝性创伤被排除在外。接受紧急开胸手术的患者(不作为初步调查/复苏的一部分)也未包括在研究中。所有数据均收集自前瞻性维护的医院登记和患者病例档案。主要结局指标为住院死亡率和影响住院死亡率的各种参数,包括但不限于患者人口统计学、院前信息、损伤特征和评分、初步调查参数和围手术期数据。次要结果测量是躯干创伤患者接受ET的临床损伤谱,包括并发症。根据变量的类别,采用Fisher精确检验、卡方检验或Wilcoxon秩和检验对数据进行分析。对决定临床结果的相关因素绘制Kaplan-Meier生存曲线。结果:67例患者接受了ET,其中大多数(94.0%)为年轻男性,中位年龄为27岁。穿透伤(61.2%)比钝器伤更常见。总生存率为46.3%,其中穿透刺伤(61.1%)损伤和孤立性胸内损伤(67.5%)患者的预后最好。接受复苏开胸术的患者预后不佳(死亡率:100%)。到达时,气道状态、心率、收缩压、生命体征和休克等血流动力学参数是有统计学意义的死亡率预测因子(p < 0.05)。幸存者功能平等性的log-rank检验显示,损伤机制(p = 0.010)、气道状态(p = 0.002)、出现时休克(p = 0.001)和初始GCS (p = 0.040)与死亡率显著相关。结论:如果根据损伤机制、主要损伤部位和生命体征仔细选择患者,ET可以成为一种预后良好的救生手术。谨慎的做法是建立一个有适当方案的系统和一个快速行动的创伤团队来执行它,以优化结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical determinants for survival following emergency thoracotomy in trauma patients: An 8-year experience from a level 1 trauma center.

Purpose: Emergency thoracotomy (ET) is a life-saving procedure performed during emergency resuscitation of patients in extremis. The controversy around such an invasive and resource-consuming procedure still lingers after so many years of its introduction. ET can serve as one of several indicators of trauma center efficiency and with information about the trauma system's overall preparedness, resources, and training. Our goal was to examine the clinical determinants of improved outcomes and review our ET experience over the past 8 years.

Methods: All patients who underwent ET during the study period from January 2014 to December 2021 at our hospital were included in this retrospective study. Patients in whom the time of arrest was not known or who had incomplete data were excluded. Also, patients with fixed, dilated pupil on arrival with a significant blunt trauma were excluded. Patients undergoing urgent thoracotomy (not as a part of primary survey/resuscitation) were also not included in the study. All data were collected from the prospectively maintained hospital registry and patient case files. The primary outcome measure was in-hospital mortality and various parameters affecting it including but not limited to patient demographics, prehospital information, injury characteristics and scores, parameters of primary survey and perioperative data. The secondary outcome measures were the clinical spectrum of injury in patients with torso trauma who underwent ET including complications. The data was analysed using Fisher's exact test, Chi-square test or Wilcoxon rank-sum test based on the category of variables. A Kaplan-Meier survival curve was plotted on relevant factors which determined clinical outcomes.

Results: Sixty-seven patients underwent ET, with the majority (94.0%) being young males with a median age of 27 years. Penetrating injuries (61.2%) were more common than blunt trauma. Overall survival was 46.3%, with the best outcomes seen with penetrating stab (61.1%) injuries and patients with isolated intrathoracic injuries (67.5%). Patients who underwent resuscitative thoracotomy had dismal outcomes (mortality: 100%). On arrival, hemodynamic parameters like airway status, heart rate, systolic blood pressure, signs of life, and shock at presentation are statistically significant predictors of mortality (p < 0.05). The log-rank test for equality of survivor functions revealed the mechanism of injury (p = 0.010), the status of the airway (p = 0.002), shock on presentation (p = 0.001), and initial GCS (p = 0.040) to be significantly associated with mortality.

Conclusion: ET can be a life-saving procedure with good outcomes, provided a careful selection of patients based on the mechanism of injury, location of major injury, and signs of life. It is prudent to have a system with proper protocol and a swiftly acting trauma team performing it to optimize the outcomes.

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来源期刊
CiteScore
3.80
自引率
4.80%
发文量
1707
审稿时长
28 weeks
期刊介绍: Chinese Journal of Traumatology (CJT, ISSN 1008-1275) was launched in 1998 and is a peer-reviewed English journal authorized by Chinese Association of Trauma, Chinese Medical Association. It is multidisciplinary and designed to provide the most current and relevant information for both the clinical and basic research in the field of traumatic medicine. CJT primarily publishes expert forums, original papers, case reports and so on. Topics cover trauma system and management, surgical procedures, acute care, rehabilitation, post-traumatic complications, translational medicine, traffic medicine and other related areas. The journal especially emphasizes clinical application, technique, surgical video, guideline, recommendations for more effective surgical approaches.
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