Yingxian Xia, Li Zhang, Yuxiang Xing, Zhiqiang Chen, Hewei Gao
{"title":"ComptoNet:用于多源平稳CT多散射估计的康普顿图引导深度学习框架。","authors":"Yingxian Xia, Li Zhang, Yuxiang Xing, Zhiqiang Chen, Hewei Gao","doi":"10.1088/1361-6560/adebd7","DOIUrl":null,"url":null,"abstract":"<p><p>Multi-source stationary computed tomography (MSS-CT) offers significant advantages in medical and industrial applications due to its gantryless scan architecture and capability of simultaneous multi-source emission. However, the lack of anti-scatter grid deployment in MSS-CT leads to severe forward and cross scatter contamination, necessitating accurate and efficient scatter correction. In this work, we propose ComptoNet, an innovative decoupled deep learning framework that integrates Compton-scattering physics with deep learning for scatter estimation in MSS-CT. The core innovation lies in the Compton-map, a representation of large-angle Compton scatter signals outside the scan field of view. ComptoNet employs a dual-network architecture: a Conditional Encoder-Decoder Network (CED-Net) guided by reference Compton-maps and spare detector data for cross scatter estimation, and a Frequency U-Net with attention mechanisms for forward scatter correction. Experiments on Monte Carlo-simulated data demonstrate ComptoNet's superior performance, achieving a mean absolute percentage error (MAPE) of $0.84\\%$ on scatter estimation. After correction, CT images show nearly artifact-free quality, validating ComptoNet's robustness in mitigating scatter-induced errors across diverse photon counts and phantoms.</p>","PeriodicalId":20185,"journal":{"name":"Physics in medicine and biology","volume":" ","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ComptoNet: a Compton-map guided deep learning framework for multi-scatter estimation in multi-source stationary CT.\",\"authors\":\"Yingxian Xia, Li Zhang, Yuxiang Xing, Zhiqiang Chen, Hewei Gao\",\"doi\":\"10.1088/1361-6560/adebd7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Multi-source stationary computed tomography (MSS-CT) offers significant advantages in medical and industrial applications due to its gantryless scan architecture and capability of simultaneous multi-source emission. However, the lack of anti-scatter grid deployment in MSS-CT leads to severe forward and cross scatter contamination, necessitating accurate and efficient scatter correction. In this work, we propose ComptoNet, an innovative decoupled deep learning framework that integrates Compton-scattering physics with deep learning for scatter estimation in MSS-CT. The core innovation lies in the Compton-map, a representation of large-angle Compton scatter signals outside the scan field of view. ComptoNet employs a dual-network architecture: a Conditional Encoder-Decoder Network (CED-Net) guided by reference Compton-maps and spare detector data for cross scatter estimation, and a Frequency U-Net with attention mechanisms for forward scatter correction. Experiments on Monte Carlo-simulated data demonstrate ComptoNet's superior performance, achieving a mean absolute percentage error (MAPE) of $0.84\\\\%$ on scatter estimation. After correction, CT images show nearly artifact-free quality, validating ComptoNet's robustness in mitigating scatter-induced errors across diverse photon counts and phantoms.</p>\",\"PeriodicalId\":20185,\"journal\":{\"name\":\"Physics in medicine and biology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physics in medicine and biology\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1088/1361-6560/adebd7\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics in medicine and biology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1088/1361-6560/adebd7","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
ComptoNet: a Compton-map guided deep learning framework for multi-scatter estimation in multi-source stationary CT.
Multi-source stationary computed tomography (MSS-CT) offers significant advantages in medical and industrial applications due to its gantryless scan architecture and capability of simultaneous multi-source emission. However, the lack of anti-scatter grid deployment in MSS-CT leads to severe forward and cross scatter contamination, necessitating accurate and efficient scatter correction. In this work, we propose ComptoNet, an innovative decoupled deep learning framework that integrates Compton-scattering physics with deep learning for scatter estimation in MSS-CT. The core innovation lies in the Compton-map, a representation of large-angle Compton scatter signals outside the scan field of view. ComptoNet employs a dual-network architecture: a Conditional Encoder-Decoder Network (CED-Net) guided by reference Compton-maps and spare detector data for cross scatter estimation, and a Frequency U-Net with attention mechanisms for forward scatter correction. Experiments on Monte Carlo-simulated data demonstrate ComptoNet's superior performance, achieving a mean absolute percentage error (MAPE) of $0.84\%$ on scatter estimation. After correction, CT images show nearly artifact-free quality, validating ComptoNet's robustness in mitigating scatter-induced errors across diverse photon counts and phantoms.
期刊介绍:
The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry