Masato Tamate, Giuliano Testa, Laura Divine, Johanna Bayer, Liza Johannesson
{"title":"活体供体子宫移植。","authors":"Masato Tamate, Giuliano Testa, Laura Divine, Johanna Bayer, Liza Johannesson","doi":"10.1097/AOG.0000000000005987","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>For women with absolute uterine factor infertility, uterus transplantation represents the closest solution to normal gestation and delivery. It is a temporary transplant; the uterine graft is removed after completion of childbearing. The uterus transplant journey involves multiple surgical and medical steps.</p><p><strong>Technique: </strong>The surgical steps include living or deceased donor hysterectomy, transplant of the uterine graft, cesarean delivery, and graft hysterectomy. The medical steps include immunosuppressive treatment, in vitro fertilization, and pregnancy. In this video, we show a living donor uterus transplant, including donor hysterectomy, back-table preparation of the uterine graft, and recipient transplant surgery. The video highlights the surgical steps of the procedure.</p><p><strong>Experience: </strong>Between September 2016 and January 2025, 36 women underwent uterus transplantation at Baylor University Medical Center, resulting in the birth of 26 children to date.</p><p><strong>Conclusion: </strong>Uterus transplantation is associated with successful births of healthy children.</p>","PeriodicalId":19483,"journal":{"name":"Obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":4.7000,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Living Donor Uterus Transplantation.\",\"authors\":\"Masato Tamate, Giuliano Testa, Laura Divine, Johanna Bayer, Liza Johannesson\",\"doi\":\"10.1097/AOG.0000000000005987\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>For women with absolute uterine factor infertility, uterus transplantation represents the closest solution to normal gestation and delivery. It is a temporary transplant; the uterine graft is removed after completion of childbearing. The uterus transplant journey involves multiple surgical and medical steps.</p><p><strong>Technique: </strong>The surgical steps include living or deceased donor hysterectomy, transplant of the uterine graft, cesarean delivery, and graft hysterectomy. The medical steps include immunosuppressive treatment, in vitro fertilization, and pregnancy. In this video, we show a living donor uterus transplant, including donor hysterectomy, back-table preparation of the uterine graft, and recipient transplant surgery. The video highlights the surgical steps of the procedure.</p><p><strong>Experience: </strong>Between September 2016 and January 2025, 36 women underwent uterus transplantation at Baylor University Medical Center, resulting in the birth of 26 children to date.</p><p><strong>Conclusion: </strong>Uterus transplantation is associated with successful births of healthy children.</p>\",\"PeriodicalId\":19483,\"journal\":{\"name\":\"Obstetrics and gynecology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":4.7000,\"publicationDate\":\"2025-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Obstetrics and gynecology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/AOG.0000000000005987\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Obstetrics and gynecology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/AOG.0000000000005987","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Background: For women with absolute uterine factor infertility, uterus transplantation represents the closest solution to normal gestation and delivery. It is a temporary transplant; the uterine graft is removed after completion of childbearing. The uterus transplant journey involves multiple surgical and medical steps.
Technique: The surgical steps include living or deceased donor hysterectomy, transplant of the uterine graft, cesarean delivery, and graft hysterectomy. The medical steps include immunosuppressive treatment, in vitro fertilization, and pregnancy. In this video, we show a living donor uterus transplant, including donor hysterectomy, back-table preparation of the uterine graft, and recipient transplant surgery. The video highlights the surgical steps of the procedure.
Experience: Between September 2016 and January 2025, 36 women underwent uterus transplantation at Baylor University Medical Center, resulting in the birth of 26 children to date.
Conclusion: Uterus transplantation is associated with successful births of healthy children.
期刊介绍：
"Obstetrics & Gynecology," affectionately known as "The Green Journal," is the official publication of the American College of Obstetricians and Gynecologists (ACOG). Since its inception in 1953, the journal has been dedicated to advancing the clinical practice of obstetrics and gynecology, as well as related fields. The journal's mission is to promote excellence in these areas by publishing a diverse range of articles that cover translational and clinical topics.
"Obstetrics & Gynecology" provides a platform for the dissemination of evidence-based research, clinical guidelines, and expert opinions that are essential for the continuous improvement of women's health care. The journal's content is designed to inform and educate obstetricians, gynecologists, and other healthcare professionals, ensuring that they stay abreast of the latest developments and best practices in their field.
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