Philipp Ruf , Özgür Cebeci , Vincenzo Orassi , Claudius Steffen , Georg N. Duda , Max Heiland , Sara Checa , Carsten Rendenbach
{"title":"预弯曲对单节段下颌骨重建一期固定稳定性的影响","authors":"Philipp Ruf , Özgür Cebeci , Vincenzo Orassi , Claudius Steffen , Georg N. Duda , Max Heiland , Sara Checa , Carsten Rendenbach","doi":"10.1016/j.compbiomed.2025.110686","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The fixation of osseous free flaps for segmental mandible reconstruction after resection is most commonly performed with patient-specific 3D printed or conventional load-bearing reconstruction plates.</div><div>The main challenge with conventional plates is the step of manual bending to adjust the plate to the specific mandible of the patient. To date, the influence of this permanent plate deformation on the biomechanical conditions within the healing regions remains unknown.</div><div>The present study aimed to investigate the effect of plate pre-bending on intersegmental strains, known to influence the healing outcome.</div></div><div><h3>Methods</h3><div>To achieve this, biomechanical finite element models were developed to simulate plate pre-bending and biting in a one-segmental mandibular reconstruction. The biomechanics induced within the healing region were compared between a pre-stressed conventional reconstruction plate and a customized conventional reconstruction plate.</div></div><div><h3>Results</h3><div>Higher stresses were predicted in the pre-stressed plate. However, the mechanical strains within the healing regions were not influenced by plate pre-bending.</div></div><div><h3>Conclusions</h3><div>The increased levels of mechanical strains under both pre-stressed and customized conventional plates in comparison to common patient-specific plates could be a reason for the higher rates of osseous union under conventional fixation. Since customized conventional reconstruction plates additionally presented elastic stresses and include the advantages of patient-specific plates, those plates are biomechanically and clinically promising.</div></div>","PeriodicalId":10578,"journal":{"name":"Computers in biology and medicine","volume":"196 ","pages":"Article 110686"},"PeriodicalIF":7.0000,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Influence of pre-bending on primary fixation stability in one-segmental mandibular reconstruction\",\"authors\":\"Philipp Ruf , Özgür Cebeci , Vincenzo Orassi , Claudius Steffen , Georg N. Duda , Max Heiland , Sara Checa , Carsten Rendenbach\",\"doi\":\"10.1016/j.compbiomed.2025.110686\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>The fixation of osseous free flaps for segmental mandible reconstruction after resection is most commonly performed with patient-specific 3D printed or conventional load-bearing reconstruction plates.</div><div>The main challenge with conventional plates is the step of manual bending to adjust the plate to the specific mandible of the patient. To date, the influence of this permanent plate deformation on the biomechanical conditions within the healing regions remains unknown.</div><div>The present study aimed to investigate the effect of plate pre-bending on intersegmental strains, known to influence the healing outcome.</div></div><div><h3>Methods</h3><div>To achieve this, biomechanical finite element models were developed to simulate plate pre-bending and biting in a one-segmental mandibular reconstruction. The biomechanics induced within the healing region were compared between a pre-stressed conventional reconstruction plate and a customized conventional reconstruction plate.</div></div><div><h3>Results</h3><div>Higher stresses were predicted in the pre-stressed plate. However, the mechanical strains within the healing regions were not influenced by plate pre-bending.</div></div><div><h3>Conclusions</h3><div>The increased levels of mechanical strains under both pre-stressed and customized conventional plates in comparison to common patient-specific plates could be a reason for the higher rates of osseous union under conventional fixation. Since customized conventional reconstruction plates additionally presented elastic stresses and include the advantages of patient-specific plates, those plates are biomechanically and clinically promising.</div></div>\",\"PeriodicalId\":10578,\"journal\":{\"name\":\"Computers in biology and medicine\",\"volume\":\"196 \",\"pages\":\"Article 110686\"},\"PeriodicalIF\":7.0000,\"publicationDate\":\"2025-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computers in biology and medicine\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0010482525010376\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computers in biology and medicine","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0010482525010376","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOLOGY","Score":null,"Total":0}
Influence of pre-bending on primary fixation stability in one-segmental mandibular reconstruction
Background
The fixation of osseous free flaps for segmental mandible reconstruction after resection is most commonly performed with patient-specific 3D printed or conventional load-bearing reconstruction plates.
The main challenge with conventional plates is the step of manual bending to adjust the plate to the specific mandible of the patient. To date, the influence of this permanent plate deformation on the biomechanical conditions within the healing regions remains unknown.
The present study aimed to investigate the effect of plate pre-bending on intersegmental strains, known to influence the healing outcome.
Methods
To achieve this, biomechanical finite element models were developed to simulate plate pre-bending and biting in a one-segmental mandibular reconstruction. The biomechanics induced within the healing region were compared between a pre-stressed conventional reconstruction plate and a customized conventional reconstruction plate.
Results
Higher stresses were predicted in the pre-stressed plate. However, the mechanical strains within the healing regions were not influenced by plate pre-bending.
Conclusions
The increased levels of mechanical strains under both pre-stressed and customized conventional plates in comparison to common patient-specific plates could be a reason for the higher rates of osseous union under conventional fixation. Since customized conventional reconstruction plates additionally presented elastic stresses and include the advantages of patient-specific plates, those plates are biomechanically and clinically promising.
期刊介绍:
Computers in Biology and Medicine is an international forum for sharing groundbreaking advancements in the use of computers in bioscience and medicine. This journal serves as a medium for communicating essential research, instruction, ideas, and information regarding the rapidly evolving field of computer applications in these domains. By encouraging the exchange of knowledge, we aim to facilitate progress and innovation in the utilization of computers in biology and medicine.