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引用次数: 0
摘要
使用电子患者报告结果（electronic patient- reporting outcomes, ePROs）进行症状监测已被证明对癌症患者有益，但对肺癌的系统性影响尚不清楚。本研究于2025年4月23日前在Medline、Embase、Cochrane library、CINAHL、APA PsyInfo等数据库进行文献检索，共检索到5755篇论文。纳入来自11项研究的18篇（0.31%）对电子病历进行症状监测并对严重症状发出警报。meta分析显示，干预时间小于6个月、6个月和大于6个月的肺癌患者健康相关生活质量均有显著改善（SMD = 2.44, P < 0.001）。当排除向患者自身发送警报的研究时，肺癌患者的总生存期显著延长（HR = 0.54, 95% CI [0.22, 1.31], P = 0.031）。症状负担、身体功能和医疗服务利用也有优势，但实施过程和成本效益数据不足（试验注册：CRD420251000397）。
Effectiveness of symptom monitoring on electronic patient-reported outcomes (ePROs) among patients with lung cancer: a systematic review and meta-analysis
Symptom monitoring using electronic patient-reported outcomes (ePROs) has demonstrated benefits for patients with cancer, yet the systematic effects for lung cancer remains unknown. This study performed a literature search in Medline, Embase, Cochrane library, CINAHL and APA PsyInfo before April 23rd, 2025, and identified 5755 papers. 18 (0.31%) papers from 11 studies conducting symptom monitoring on ePROs and sending alerts of severe symptoms were included. The meta-analysis showed significant improvement in health-related quality of life (SMD = 2.44, P < 0.001) among patients with lung cancer, with an intervention duration of less than 6 months, 6 months and more than 6 months. When excluding studies that sent alerts to patients themselves, overall survival for lung cancer patients was significantly prolonged (HR = 0.54, 95% CI [0.22, 1.31], P = 0.031). Symptom burden, physical functioning, and healthcare service utilization was also advantaged, but implementation process and cost-effectiveness data was insufficient (Trial registration: CRD420251000397).
期刊介绍：
npj Digital Medicine is an online open-access journal that focuses on publishing peer-reviewed research in the field of digital medicine. The journal covers various aspects of digital medicine, including the application and implementation of digital and mobile technologies in clinical settings, virtual healthcare, and the use of artificial intelligence and informatics.
The primary goal of the journal is to support innovation and the advancement of healthcare through the integration of new digital and mobile technologies. When determining if a manuscript is suitable for publication, the journal considers four important criteria: novelty, clinical relevance, scientific rigor, and digital innovation.
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