{"title":"超越抵抗:局灶性癫痫的早期手术","authors":"Felix Benninger, Ilan Goldberg","doi":"10.1093/brain/awaf250","DOIUrl":null,"url":null,"abstract":"Benninger and Goldberg argue that early surgery for lesional focal epilepsy should be considered even before the emergence of drug resistance. They note that despite seizure control, long-term use of anti-seizure medications carries health and social burdens, while modern surgery is safe, effective, and often curative.","PeriodicalId":9063,"journal":{"name":"Brain","volume":"6 1","pages":""},"PeriodicalIF":11.7000,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Beyond resistance: early surgery for focal epilepsy\",\"authors\":\"Felix Benninger, Ilan Goldberg\",\"doi\":\"10.1093/brain/awaf250\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Benninger and Goldberg argue that early surgery for lesional focal epilepsy should be considered even before the emergence of drug resistance. They note that despite seizure control, long-term use of anti-seizure medications carries health and social burdens, while modern surgery is safe, effective, and often curative.\",\"PeriodicalId\":9063,\"journal\":{\"name\":\"Brain\",\"volume\":\"6 1\",\"pages\":\"\"},\"PeriodicalIF\":11.7000,\"publicationDate\":\"2025-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brain\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/brain/awaf250\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/brain/awaf250","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Beyond resistance: early surgery for focal epilepsy
Benninger and Goldberg argue that early surgery for lesional focal epilepsy should be considered even before the emergence of drug resistance. They note that despite seizure control, long-term use of anti-seizure medications carries health and social burdens, while modern surgery is safe, effective, and often curative.
期刊介绍:
Brain, a journal focused on clinical neurology and translational neuroscience, has been publishing landmark papers since 1878. The journal aims to expand its scope by including studies that shed light on disease mechanisms and conducting innovative clinical trials for brain disorders. With a wide range of topics covered, the Editorial Board represents the international readership and diverse coverage of the journal. Accepted articles are promptly posted online, typically within a few weeks of acceptance. As of 2022, Brain holds an impressive impact factor of 14.5, according to the Journal Citation Reports.