Martins Lauskis , Oskars Radzins , Sergio E. Uribe , Simonas Grybauskas , Girts Salms
{"title":"双相hap/β-tcp/胶原植入体隆胸的体积稳定性:正颌手术后基于cbct的病例系列。","authors":"Martins Lauskis , Oskars Radzins , Sergio E. Uribe , Simonas Grybauskas , Girts Salms","doi":"10.1016/j.jcms.2025.06.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>Evaluate volumetric stability and symmetry of Biphasic Hydroxyapatite (HAp)/β-Tricalcium phosphate (β-TCP)/collagen (BCP-collagen) implants in malar augmentation post-orthognathic surgery over one year using Cone-Beam-CT (CBCT) and explore influencing factors.</div></div><div><h3>Methods</h3><div>Retrospective case-series analysis of 45 patients (38 females) who underwent bimaxillary orthognathic surgery with malar augmentation using BCP-collagen implants. CBCT scans were taken at 1 week, 4 months, and 12 months post-surgery. Regression analysis explored potential factors influencing volume loss, including age and sex (p < 0.05).</div></div><div><h3>Results</h3><div>Median patient-age was 26 years (IQR: 22–32). One week postoperatively, median implant-volume was 1356.70 mm<sup>3</sup> (SD = 5888.53). By four-months, it decreased to 985.46 mm<sup>3</sup> (SD = 4352.47), a 25.4 % reduction (p < 0.001). Afterwards, a 1.3 % volume decrease (p = 0.42). Volume loss varied between 35.1 and 14.7 %. Asymmetry >7 % was observed in 17.7 % of patients. No significant differences in volume loss were found between sexes (p = 0.6) or age groups (p > 0.9). Regression showed no significant associations with age (β = 0.02, 95 %CI: −0.48, 0.53, p > 0.9) or sex (β = 11, 95 %CI: −30, 52, p = 0.6).</div></div><div><h3>Conclusion</h3><div>BCP-collagen implants exhibit early volume loss but stabilise long-term. High variability and asymmetry in volumetric changes challenge standard overcorrection strategies, emphasising the need for early monitoring. CBCT enables precise volumetric assessment and may improve surgical decision-making.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"53 9","pages":"Pages 1530-1537"},"PeriodicalIF":2.1000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Volumetric stability of biphasic hap/β-tcp/collagen implants in malar augmentation: A CBCT-Based case series after orthognathic surgery\",\"authors\":\"Martins Lauskis , Oskars Radzins , Sergio E. Uribe , Simonas Grybauskas , Girts Salms\",\"doi\":\"10.1016/j.jcms.2025.06.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>Evaluate volumetric stability and symmetry of Biphasic Hydroxyapatite (HAp)/β-Tricalcium phosphate (β-TCP)/collagen (BCP-collagen) implants in malar augmentation post-orthognathic surgery over one year using Cone-Beam-CT (CBCT) and explore influencing factors.</div></div><div><h3>Methods</h3><div>Retrospective case-series analysis of 45 patients (38 females) who underwent bimaxillary orthognathic surgery with malar augmentation using BCP-collagen implants. CBCT scans were taken at 1 week, 4 months, and 12 months post-surgery. Regression analysis explored potential factors influencing volume loss, including age and sex (p < 0.05).</div></div><div><h3>Results</h3><div>Median patient-age was 26 years (IQR: 22–32). One week postoperatively, median implant-volume was 1356.70 mm<sup>3</sup> (SD = 5888.53). By four-months, it decreased to 985.46 mm<sup>3</sup> (SD = 4352.47), a 25.4 % reduction (p < 0.001). Afterwards, a 1.3 % volume decrease (p = 0.42). Volume loss varied between 35.1 and 14.7 %. Asymmetry >7 % was observed in 17.7 % of patients. No significant differences in volume loss were found between sexes (p = 0.6) or age groups (p > 0.9). Regression showed no significant associations with age (β = 0.02, 95 %CI: −0.48, 0.53, p > 0.9) or sex (β = 11, 95 %CI: −30, 52, p = 0.6).</div></div><div><h3>Conclusion</h3><div>BCP-collagen implants exhibit early volume loss but stabilise long-term. High variability and asymmetry in volumetric changes challenge standard overcorrection strategies, emphasising the need for early monitoring. CBCT enables precise volumetric assessment and may improve surgical decision-making.</div></div>\",\"PeriodicalId\":54851,\"journal\":{\"name\":\"Journal of Cranio-Maxillofacial Surgery\",\"volume\":\"53 9\",\"pages\":\"Pages 1530-1537\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cranio-Maxillofacial Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S101051822500201X\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cranio-Maxillofacial Surgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S101051822500201X","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Volumetric stability of biphasic hap/β-tcp/collagen implants in malar augmentation: A CBCT-Based case series after orthognathic surgery
Objective
Evaluate volumetric stability and symmetry of Biphasic Hydroxyapatite (HAp)/β-Tricalcium phosphate (β-TCP)/collagen (BCP-collagen) implants in malar augmentation post-orthognathic surgery over one year using Cone-Beam-CT (CBCT) and explore influencing factors.
Methods
Retrospective case-series analysis of 45 patients (38 females) who underwent bimaxillary orthognathic surgery with malar augmentation using BCP-collagen implants. CBCT scans were taken at 1 week, 4 months, and 12 months post-surgery. Regression analysis explored potential factors influencing volume loss, including age and sex (p < 0.05).
Results
Median patient-age was 26 years (IQR: 22–32). One week postoperatively, median implant-volume was 1356.70 mm3 (SD = 5888.53). By four-months, it decreased to 985.46 mm3 (SD = 4352.47), a 25.4 % reduction (p < 0.001). Afterwards, a 1.3 % volume decrease (p = 0.42). Volume loss varied between 35.1 and 14.7 %. Asymmetry >7 % was observed in 17.7 % of patients. No significant differences in volume loss were found between sexes (p = 0.6) or age groups (p > 0.9). Regression showed no significant associations with age (β = 0.02, 95 %CI: −0.48, 0.53, p > 0.9) or sex (β = 11, 95 %CI: −30, 52, p = 0.6).
Conclusion
BCP-collagen implants exhibit early volume loss but stabilise long-term. High variability and asymmetry in volumetric changes challenge standard overcorrection strategies, emphasising the need for early monitoring. CBCT enables precise volumetric assessment and may improve surgical decision-making.
期刊介绍:
The Journal of Cranio-Maxillofacial Surgery publishes articles covering all aspects of surgery of the head, face and jaw. Specific topics covered recently have included:
• Distraction osteogenesis
• Synthetic bone substitutes
• Fibroblast growth factors
• Fetal wound healing
• Skull base surgery
• Computer-assisted surgery
• Vascularized bone grafts