Teng Wang, Hanxu Shi, Zhisheng Liang, Haojun Fan, Taojiang Meng, Fan Dai, Wei Huang, Ming Xu, Huining Yang, Shyam Biswal, Murugappan Ramanathan, Gorden G Liu, Minghui Ren, Shengzhi Sun, Zhenyu Zhang
{"title":"潮湿热浪与缺血性心脏病之间的因果关系:评估中国955个县的住院率和经济负担","authors":"Teng Wang, Hanxu Shi, Zhisheng Liang, Haojun Fan, Taojiang Meng, Fan Dai, Wei Huang, Ming Xu, Huining Yang, Shyam Biswal, Murugappan Ramanathan, Gorden G Liu, Minghui Ren, Shengzhi Sun, Zhenyu Zhang","doi":"10.1186/s12916-025-04133-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Humid heatwaves might cause more massive destruction to human health systems, especially the cardiovascular system. However, there is no systematic approach for identifying humid heatwaves and assessing their impacts on human health and health-related economic burden. This study aims to elucidate the relationship between short-term exposure to humid heatwaves and the relative risk of hospitalization for ischemic heart disease (IHD) and the hospitalization-related economic burdens.</p><p><strong>Methods: </strong>This study utilizes hospitalization data from the Chinese Multiple-County (CMC) Hospital Network with 6,843,511 IHD cases across 1309 counties from 2016 to 2022. We employed a pre-post analysis and a causal inferential propensity score matching aided difference-in-differences (PSM-DID) approach to assess the causal effect of each type of humid heatwaves on IHD hospitalization rate changes.</p><p><strong>Results: </strong>IHD hospitalizations increased by 2.92% (95% CI, 1.17%, 4.66%), 2.76% (95% CI, 1.07%, 4.45%), and 1.60% (95% CI, 0.08%, 3.12%) following independent humid heatwaves, light precipitation involved-, and moderate precipitation involved-humid heatwaves, with annual hospitalization-related economic burden reached $154 million (95% CI, $20, $249 million), $75 million (95% CI, $14, $136 million), and $81 million (95% CI, $31, $131 million), respectively. Chronic IHD and Angina were the most sensitive subtypes. Moreover, middle-to-old and male populations were afforded the most burdens.</p><p><strong>Conclusions: </strong>As humid heatwaves become more intense, older populations with IHD should be provided with more care and medical resources. Identifying strategies and implementing actionable adaptation measures to minimize disruptions in healthcare delivery following these extremely hot and humid events is crucial to reducing IHD hospitalizations.</p>","PeriodicalId":9188,"journal":{"name":"BMC Medicine","volume":"23 1","pages":"359"},"PeriodicalIF":7.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211259/pdf/","citationCount":"0","resultStr":"{\"title\":\"Causal link between humid heatwaves and ischemic heart disease: assessing hospitalizations and economic burden across 955 Chinese counties.\",\"authors\":\"Teng Wang, Hanxu Shi, Zhisheng Liang, Haojun Fan, Taojiang Meng, Fan Dai, Wei Huang, Ming Xu, Huining Yang, Shyam Biswal, Murugappan Ramanathan, Gorden G Liu, Minghui Ren, Shengzhi Sun, Zhenyu Zhang\",\"doi\":\"10.1186/s12916-025-04133-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Humid heatwaves might cause more massive destruction to human health systems, especially the cardiovascular system. However, there is no systematic approach for identifying humid heatwaves and assessing their impacts on human health and health-related economic burden. This study aims to elucidate the relationship between short-term exposure to humid heatwaves and the relative risk of hospitalization for ischemic heart disease (IHD) and the hospitalization-related economic burdens.</p><p><strong>Methods: </strong>This study utilizes hospitalization data from the Chinese Multiple-County (CMC) Hospital Network with 6,843,511 IHD cases across 1309 counties from 2016 to 2022. We employed a pre-post analysis and a causal inferential propensity score matching aided difference-in-differences (PSM-DID) approach to assess the causal effect of each type of humid heatwaves on IHD hospitalization rate changes.</p><p><strong>Results: </strong>IHD hospitalizations increased by 2.92% (95% CI, 1.17%, 4.66%), 2.76% (95% CI, 1.07%, 4.45%), and 1.60% (95% CI, 0.08%, 3.12%) following independent humid heatwaves, light precipitation involved-, and moderate precipitation involved-humid heatwaves, with annual hospitalization-related economic burden reached $154 million (95% CI, $20, $249 million), $75 million (95% CI, $14, $136 million), and $81 million (95% CI, $31, $131 million), respectively. Chronic IHD and Angina were the most sensitive subtypes. Moreover, middle-to-old and male populations were afforded the most burdens.</p><p><strong>Conclusions: </strong>As humid heatwaves become more intense, older populations with IHD should be provided with more care and medical resources. Identifying strategies and implementing actionable adaptation measures to minimize disruptions in healthcare delivery following these extremely hot and humid events is crucial to reducing IHD hospitalizations.</p>\",\"PeriodicalId\":9188,\"journal\":{\"name\":\"BMC Medicine\",\"volume\":\"23 1\",\"pages\":\"359\"},\"PeriodicalIF\":7.0000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211259/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12916-025-04133-8\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12916-025-04133-8","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Causal link between humid heatwaves and ischemic heart disease: assessing hospitalizations and economic burden across 955 Chinese counties.
Background: Humid heatwaves might cause more massive destruction to human health systems, especially the cardiovascular system. However, there is no systematic approach for identifying humid heatwaves and assessing their impacts on human health and health-related economic burden. This study aims to elucidate the relationship between short-term exposure to humid heatwaves and the relative risk of hospitalization for ischemic heart disease (IHD) and the hospitalization-related economic burdens.
Methods: This study utilizes hospitalization data from the Chinese Multiple-County (CMC) Hospital Network with 6,843,511 IHD cases across 1309 counties from 2016 to 2022. We employed a pre-post analysis and a causal inferential propensity score matching aided difference-in-differences (PSM-DID) approach to assess the causal effect of each type of humid heatwaves on IHD hospitalization rate changes.
Results: IHD hospitalizations increased by 2.92% (95% CI, 1.17%, 4.66%), 2.76% (95% CI, 1.07%, 4.45%), and 1.60% (95% CI, 0.08%, 3.12%) following independent humid heatwaves, light precipitation involved-, and moderate precipitation involved-humid heatwaves, with annual hospitalization-related economic burden reached $154 million (95% CI, $20, $249 million), $75 million (95% CI, $14, $136 million), and $81 million (95% CI, $31, $131 million), respectively. Chronic IHD and Angina were the most sensitive subtypes. Moreover, middle-to-old and male populations were afforded the most burdens.
Conclusions: As humid heatwaves become more intense, older populations with IHD should be provided with more care and medical resources. Identifying strategies and implementing actionable adaptation measures to minimize disruptions in healthcare delivery following these extremely hot and humid events is crucial to reducing IHD hospitalizations.
期刊介绍:
BMC Medicine is an open access, transparent peer-reviewed general medical journal. It is the flagship journal of the BMC series and publishes outstanding and influential research in various areas including clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. In addition to research articles, the journal also publishes stimulating debates, reviews, unique forum articles, and concise tutorials. All articles published in BMC Medicine are included in various databases such as Biological Abstracts, BIOSIS, CAS, Citebase, Current contents, DOAJ, Embase, MEDLINE, PubMed, Science Citation Index Expanded, OAIster, SCImago, Scopus, SOCOLAR, and Zetoc.