探讨定量弹性成像的局限性:拉伸软条的超声剪切成像。

IF 3.4 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Samuel Croquette, Alexandre Delory, Daniel A Kiefer, Claire Prada, Fabrice Lemoult
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引用次数: 0

摘要

目的——横波弹性成像丰富了超声医学成像的定量组织刚度测量。我们的目标是探索与粘弹性、导向几何或静态变形相关的持续限制。方法——选择一种几乎不可压缩的软弹性体条来模拟拉长组织的机械行为。超声波横波扫描仪测量横波在带材内的传播。根据频率、静态应变和条带的方向,它提供了从2到6~m/s的大范围横波速度。主要结果——为了解释这些不同的测量结果,我们强调了导波效应,并从原始数据的时空傅里叶变换提供的色散图中进行了分析。然后使用考虑流变学和超弹性行为的材料模型来描述导波,并允许提取样品的力学参数。意义——为了克服当前弹性学的一些局限性,我们提出了一个理论框架,该框架允许同时表征软组织的粘弹性和超弹性特性,为细长组织的稳健定量弹性学铺平了道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring the limits to quantitative elastography: supersonic shear imaging in stretched soft strips.

Objective.Shear wave elastography has enriched ultrasound medical imaging with quantitative tissue stiffness measurements. We aim to explore the limitations that persist related to viscoelasticity, guiding geometry or static deformation.Approach.A nearly-incompressible soft elastomer strip is chosen to mimic the mechanical behaviour of an elongated tissue. A supersonic shear wave scanner measures the propagation of shear waves within the strip. It provides a wide range of shear wave velocities, from 2 to 6 m s-1, depending on the frequency, the static strain as well as the orientation of the strip.Main results.To explain these different measurements, the guided wave effect is highlighted and analysed from the dispersion diagrams provided by the spatio-temporal Fourier transform of the raw data. The guided waves are then described using a material model that accounts for both the rheology and the hyperelastic behaviour, and allows to extract the mechanical parameters of the sample.Significance.To overcome some limitations of current elastography, we propose a theoretical framework which allows the simultaneous characterization of the viscoelastic and hyperelastic properties of soft tissues, paving the way for robust quantitative elastography of elongated tissues.

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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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