可见光促进铜催化的能量转移芳基溴醚化反应。

IF 5 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2025-06-30 DOI:10.1021/acs.orglett.5c01919

Xiantong Yao, Ruiyuan Peng, Xin Yang, Jinheng Zheng, Weijun Zhong, Qinghua Zhong, Zhengjie Wang, Dali Yang, Ruihua Cheng, Yueyue Ma* and Jinxing Ye*,

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引用次数: 0

摘要

以紫红Y为光敏剂，建立了一种可见光促进铜催化的醇与芳基溴的C-O偶联反应，其中从紫红Y到草酰胺配体铜配合物的能量转移（EnT）产生激发态铜配合物，促进芳基溴的氧化加成。这种温和的方法可以在室温下高效地合成烷基芳醚和联芳醚，具有广泛的底物范围和对敏感官能团的优异耐受性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Visible-Light-Promoted Copper-Catalyzed Etherification of Aryl Bromides via Energy Transfer

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Visible-Light-Promoted Copper-Catalyzed Etherification of Aryl Bromides via Energy Transfer

A visible-light-promoted copper-catalyzed C–O coupling reaction of alcohols with aryl bromides using eosin Y as the photosensitizer has been developed, in which energy transfer (EnT) from eosin Y to the copper complex of the oxalamide ligand generates an excited-state copper complex that facilitates oxidative addition of aryl bromides. This mild method enables the efficient synthesis of alkyl aryl ethers and biaryl ethers with a broad substrate scope and excellent tolerance of sensitive functional groups at room temperature.

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.