Maha Hameed, Ahmad Iftikhar, Sakina Abbas, Zohaa Faiz, Fathima Shehnaz Ayoobkhan, Sameer Siddiqui, Muhammad Affan Elahi, Shaista Khadim, Faiz Anwer, Muhammad Husnain
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Plasmablastic Lymphoma-A Crosstalk Between Myeloma and Lymphoma.
Plasmablastic lymphoma (PBL) is a rare type of large B-cell lymphoma that primarily affects immunocompromised individuals, often associated with viral infections such as Human Immunodeficiency Virus (HIV) and Epstein-Barr Virus (EBV). The diagnosis of PBL is often difficult to ascertain due to its overlapping clinical and pathological features with multiple myeloma and large B cell lymphoma. The primary organs of involvement are typically the gastrointestinal system, lymph nodes, oral mucosa, with some involvement of the skin. This review explores the critical aspects of plasmablastic lymphoma, including its clinical features, diagnosis, treatment options, and the latest advancements for this rare disease. Understanding plasmablastic lymphoma is necessary for healthcare professionals and patients alike to improve the outcomes and quality of life for those affected by this aggressive form of lymphoma.
期刊介绍：
Clinical Lymphoma, Myeloma & Leukemia is a peer-reviewed monthly journal that publishes original articles describing various aspects of clinical and translational research of lymphoma, myeloma and leukemia. Clinical Lymphoma, Myeloma & Leukemia is devoted to articles on detection, diagnosis, prevention, and treatment of lymphoma, myeloma, leukemia and related disorders including macroglobulinemia, amyloidosis, and plasma-cell dyscrasias. The main emphasis is on recent scientific developments in all areas related to lymphoma, myeloma and leukemia. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.
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