更好地与公众沟通:将科学恐惧症和不信任理解为神经生物学现象。

IF 7.7 1区 医学 Q1 CLINICAL NEUROLOGY
Neurology Pub Date : 2025-07-22 Epub Date: 2025-06-26 DOI:10.1212/WNL.0000000000213862
Nina F Schor
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引用次数: 0

摘要

最近写了很多关于科学的不信任和文盲,以及由此产生的对科学的建议和干预的恐惧。无论是强化还是逆转这些现象,都取决于针对产生这些现象的大脑网络的策略。特定恐惧症的神经发生涉及一个网络,包括杏仁核和下丘脑,以及它们通过终纹的连接。gaba能抑制的减少导致边缘激活和恐惧通路的诱导。不信任的神经发生涉及到对一个网络的抑制,该网络包括中央杏仁核和伏隔核的外壳,这两个区域都富含催产素受体并产生多巴胺能输出。催产素信号介导信任,然而,至少在男性中,二氢睾酮信号介导不信任。科学恐惧症和不信任都可能涉及这些边缘回路,这可能是情感集中的交流在强化它们方面的高效率的基础。然而,最近扭转科学恐惧症和不信任的努力更多地涉及以智力为重点的交流。假设科学恐惧症和不信任的边缘网络起源,这篇评论提出并讨论了使用情感集中的沟通和明确的、公开的操纵技术和暗示来影响这些现象的流行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Better Communication With the Public: Understanding Science Phobia and Mistrust as Neurobiological Phenomena.

Much has been written recently about science mistrust and illiteracy and consequent phobia of recommendations and interventions that have grown out of that science. Both reinforcing and reversing these phenomena depend on strategies aimed at brain networks that generate them. The neurogenesis of specific phobias involves a network that includes the amygdala and the hypothalamus and their connection through the stria terminalis. Decreased GABAergic inhibition of this circuit results in limbic activation and induction of fear pathways. The neurogenesis of mistrust involves suppression of a network that includes the central amygdala and the shell of the nucleus accumbens, both of which are rich in oxytocin receptors and yield dopaminergic output. Oxytocin signaling mediates trust, whereas, at least in men, dihydrotestosterone signaling mediates mistrust. The possibility of involvement of these limbic circuits in both science phobia and mistrust may underlie the high efficacy of emotionally focused communication in reinforcing them. Yet, recent efforts to reverse science phobia and mistrust have more often involved intellectually focused communication. Assuming limbic network origins of science phobia and mistrust, this commentary presents and discusses the use of emotionally focused communication and explicit, public identification of manipulative techniques and innuendo to influence the prevalence of these phenomena.

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来源期刊
Neurology
Neurology 医学-临床神经学
CiteScore
12.20
自引率
4.00%
发文量
1973
审稿时长
2-3 weeks
期刊介绍: Neurology, the official journal of the American Academy of Neurology, aspires to be the premier peer-reviewed journal for clinical neurology research. Its mission is to publish exceptional peer-reviewed original research articles, editorials, and reviews to improve patient care, education, clinical research, and professionalism in neurology. As the leading clinical neurology journal worldwide, Neurology targets physicians specializing in nervous system diseases and conditions. It aims to advance the field by presenting new basic and clinical research that influences neurological practice. The journal is a leading source of cutting-edge, peer-reviewed information for the neurology community worldwide. Editorial content includes Research, Clinical/Scientific Notes, Views, Historical Neurology, NeuroImages, Humanities, Letters, and position papers from the American Academy of Neurology. The online version is considered the definitive version, encompassing all available content. Neurology is indexed in prestigious databases such as MEDLINE/PubMed, Embase, Scopus, Biological Abstracts®, PsycINFO®, Current Contents®, Web of Science®, CrossRef, and Google Scholar.
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