冠状动脉微血管功能障碍：关注病理生理机制和最新诊断技术。

IF 1.6 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiovascular Revascularization Medicine Pub Date : 2025-06-16 DOI:10.1016/j.carrev.2025.06.015

Gianluca Mincione, Matteo Maurina, Alice Benedetti, Mauro Chiarito, Giulio G Stefanini, Pieter C Smits, Valeria Paradies

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引用次数: 0

摘要

在介入心脏病学中，我们的工作传统上集中于治疗心外膜冠状动脉的病变，这些病变可以通过冠状动脉造影显示。然而，相当大比例的患者经历与心外膜冠状动脉病变相似的症状，但没有任何血管造影可见的冠状动脉疾病。这些病例属于冠状动脉微血管功能障碍。在这篇综述中，我们将探讨疾病的病理生理学，并根据不同的内窥镜类型在诊断方法和治疗策略方面的新领域。

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Coronary microvascular dysfunction: Focus on pathophysiological mechanisms and recent diagnostic techniques.

In interventional cardiology, our efforts have traditionally centered on treating lesions in the epicardial coronary arteries, which can be visualized on coronary angiography. However, a significant proportion of patients experience similar symptoms to those with epicardial coronary artery lesions, yet without any angiographically visible coronary artery disease. These cases fall under the spectrum of coronary microvascular dysfunction. In this review, we will explore the disease's pathophysiology and focus on new frontiers in terms of diagnostic approaches and therapeutic strategies according to different endotypes.

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来源期刊

Cardiovascular Revascularization Medicine CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

3.30

自引率

5.90%

发文量

687

审稿时长

36 days

期刊介绍： Cardiovascular Revascularization Medicine (CRM) is an international and multidisciplinary journal that publishes original laboratory and clinical investigations related to revascularization therapies in cardiovascular medicine. Cardiovascular Revascularization Medicine publishes articles related to preclinical work and molecular interventions, including angiogenesis, cell therapy, pharmacological interventions, restenosis management, and prevention, including experiments conducted in human subjects, in laboratory animals, and in vitro. Specific areas of interest include percutaneous angioplasty in coronary and peripheral arteries, intervention in structural heart disease, cardiovascular surgery, etc.