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基因背景漂移确定药物靶点以减轻癌症治疗耐药性

IF 48.8 1区 医学 Q1 CELL BIOLOGY
Cancer Cell Pub Date : 2025-06-26 DOI:10.1016/j.ccell.2025.06.005
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引用次数: 0

摘要

癌症治疗经常失败，因为不同疗法的组合会引发难以预测的复杂耐药性机制。我们介绍RE…
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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Gene context drift identifies drug targets to mitigate cancer treatment resistance
Cancer treatment often fails because combinations of different therapies evoke complex resistance mechanisms that are hard to predict. We introduce RE…
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来源期刊
Cancer Cell
Cancer Cell 医学-肿瘤学
CiteScore
55.20
自引率
1.20%
发文量
179
审稿时长
4-8 weeks
期刊介绍： Cancer Cell is a journal that focuses on promoting major advances in cancer research and oncology. The primary criteria for considering manuscripts are as follows: Major advances: Manuscripts should provide significant advancements in answering important questions related to naturally occurring cancers. Translational research: The journal welcomes translational research, which involves the application of basic scientific findings to human health and clinical practice. Clinical investigations: Cancer Cell is interested in publishing clinical investigations that contribute to establishing new paradigms in the treatment, diagnosis, or prevention of cancers. Insights into cancer biology: The journal values clinical investigations that provide important insights into cancer biology beyond what has been revealed by preclinical studies. Mechanism-based proof-of-principle studies: Cancer Cell encourages the publication of mechanism-based proof-of-principle clinical studies, which demonstrate the feasibility of a specific therapeutic approach or diagnostic test.
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