Weily Soong, Dhaval Patil, Jonathan Rodrigues, Ravneet K Kohli, Kathryn Krupsky, Shaloo Gupta, Bridget L Balkaran, Maria-Magdalena Balp
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Outcome measures included the 36-item Short-Form Survey version 2 (SF-36v2; mental and physical component summary [MCS and PCS] scores), Work Productivity and Activity Impairment (WPAI), and healthcare resource utilization (HCRU).</p><p><strong>Results: </strong>Among 74,994 respondents (CSU <i>N</i> = 371; AD <i>N</i> = 549; PSO <i>N</i> = 2061), mean (standard deviation [SD]) age at data collection was 41.7 (14.0), 48.4 (16.3), and 51.4 (16.6) years for CSU, AD, and PSO, respectively. Mean (standard error [SE]) MCS and PCS scores were lower (worse) among respondents with physician-diagnosed CSU <i>vs.</i> AD and PSO, respectively: MCS: 41.3 (0.6) <i>vs</i>. 44.8 (0.5) <i>vs</i>. 45.3 (0.2); PCS: 42.1 (0.5) <i>vs</i>. 47.8 (0.4) <i>vs.</i> 47.7 (0.2); all <i>p</i> < 0.001. Respondents with CSU reported higher (<i>p</i> < 0.001) work and activity impairment and HCRU <i>vs.</i> respondents with AD or PSO.</p><p><strong>Conclusion: </strong>After adjusting for confounders, respondents with CSU experienced higher humanistic and economic burden compared with respondents with AD or PSO, indicating a need for new treatments and improved clinical management.</p>","PeriodicalId":94235,"journal":{"name":"The Journal of dermatological treatment","volume":"36 1","pages":"2517384"},"PeriodicalIF":0.0000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Burden of chronic spontaneous urticaria relative to atopic dermatitis and psoriasis in the United States.\",\"authors\":\"Weily Soong, Dhaval Patil, Jonathan Rodrigues, Ravneet K Kohli, Kathryn Krupsky, Shaloo Gupta, Bridget L Balkaran, Maria-Magdalena Balp\",\"doi\":\"10.1080/09546634.2025.2517384\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To evaluate the burden of chronic spontaneous urticaria (CSU) compared with atopic dermatitis (AD) and psoriasis (PSO).</p><p><strong>Methods: </strong>This retrospective, cross-sectional study used real-world data from adult respondents from the 2019 US National Health and Wellness Survey (NHWS). 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引用次数: 0
摘要
目的：比较慢性自发性荨麻疹（CSU）与特应性皮炎（AD）和银屑病（PSO）的负担。方法：这项回顾性横断面研究使用了2019年美国国家健康与健康调查（NHWS）中成年受访者的真实数据。结果测量包括36项简短形式调查版本2 (SF-36v2；精神和身体成分总结[MCS和PCS]分数)、工作效率和活动障碍（WPAI）和医疗保健资源利用（HCRU）。结果：74,994名调查对象(CSU N = 371；AD n = 549；PSO N = 2061)，数据收集时CSU、AD和PSO的平均年龄（标准差[SD]）分别为41.7岁（14.0岁）、48.4岁（16.3岁）和51.4岁（16.6岁）。平均（标准误差[SE]） MCS和PCS评分较低（较差），分别为：MCS: 41.3 (0.6) vs. 44.8 (0.5) vs. 45.3 (0.2)；PCS: 42.1 (0.5) vs 47.8 (0.4) vs 47.7 (0.2)；所有的p p vs。患有AD或PSO的受访者。结论：在调整混杂因素后，与AD或PSO患者相比，CSU患者的人文和经济负担更高，这表明需要新的治疗方法和改进临床管理。
Burden of chronic spontaneous urticaria relative to atopic dermatitis and psoriasis in the United States.
Purpose: To evaluate the burden of chronic spontaneous urticaria (CSU) compared with atopic dermatitis (AD) and psoriasis (PSO).
Methods: This retrospective, cross-sectional study used real-world data from adult respondents from the 2019 US National Health and Wellness Survey (NHWS). Outcome measures included the 36-item Short-Form Survey version 2 (SF-36v2; mental and physical component summary [MCS and PCS] scores), Work Productivity and Activity Impairment (WPAI), and healthcare resource utilization (HCRU).
Results: Among 74,994 respondents (CSU N = 371; AD N = 549; PSO N = 2061), mean (standard deviation [SD]) age at data collection was 41.7 (14.0), 48.4 (16.3), and 51.4 (16.6) years for CSU, AD, and PSO, respectively. Mean (standard error [SE]) MCS and PCS scores were lower (worse) among respondents with physician-diagnosed CSU vs. AD and PSO, respectively: MCS: 41.3 (0.6) vs. 44.8 (0.5) vs. 45.3 (0.2); PCS: 42.1 (0.5) vs. 47.8 (0.4) vs. 47.7 (0.2); all p < 0.001. Respondents with CSU reported higher (p < 0.001) work and activity impairment and HCRU vs. respondents with AD or PSO.
Conclusion: After adjusting for confounders, respondents with CSU experienced higher humanistic and economic burden compared with respondents with AD or PSO, indicating a need for new treatments and improved clinical management.
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