促进母乳喂养期间的安全用药：社区药房无控制的前后干预研究

IF 2.6 3区医学 Q1 NURSING

Midwifery Pub Date : 2025-06-19 DOI:10.1016/j.midw.2025.104497

Milena Kovačević , Ljiljana Stanković , Branko Petrović , Aleksandra Catić Đorđević , Sandra Vezmar Kovačević , Branislava Miljković

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引用次数: 0

摘要

由于缺乏信息或对药物影响的不合理恐惧，母乳喂养的母亲要么停止服用药物，要么在服用药物的同时停止/中断母乳喂养。目的本研究的目的是调查和评估社区药剂师通过循证干预措施在促进母乳喂养母亲安全用药方面的作用。方法于2022年进行前瞻性非对照干预前后研究。第一阶段包括对社区药剂师进行为期一天的全面培训。第二阶段涉及提供药物保健服务和提供文件。研究结果和讨论共有1243名母乳喂养的母亲参与了这项研究。过敏、疼痛、喉咙痛、咳嗽和尿路感染是最常见的主诉。共有746名母亲（60.0%）在母乳喂养期间服用过药物。最常用的药物是抗感染药物（15.1%）和呼吸系统药物（10.9%）。略多于一半的母亲表示，她们没有从医生那里得到关于母乳喂养期间服药的具体建议（52.8%）。药剂师提供了各种干预措施，例如在提供处方药物的同时提供母乳喂养咨询（41.8%），出于安全原因建议更换药物或补充（15.3%），以及为监测婴儿提供量身定制的建议（40.1%）。药剂师的干预，包括使用替代药物/补充剂，导致高风险药物的使用频率下降(从1%降至0.3%,p <；0.001)。结论社区药师在母乳喂养母亲的护理中发挥着重要作用。除了提供母乳喂养咨询和支持外，社区药剂师还通过使用相关信息来源显著提高了所服用药物的安全性。

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Promoting safe medication use during breastfeeding: uncontrolled interventional before-after study in community pharmacies

Background

Due to a lack of information or unreasonable fear of the effects of medication, breastfeeding mothers either stop taking medication or discontinue/interrupt breastfeeding while taking medication.

Aim

The aim of the study was to investigate and evaluate the role of community pharmacists in promoting safe medication use among breastfeeding mothers through evidence-based interventions.

Methods

The prospective uncontrolled interventional before- and after- study was conducted in 2022. The first phase involved a one-day comprehensive training session for community pharmacists. The second phase involved the provision and documentation of pharmaceutical care services.

Findings and discussion

A total of 1243 breastfeeding mothers participated in the study. Allergy, pain, sore throat, cough and urinary tract infections were the most common complaints. A total of 746 mothers (60.0 %) had been prescribed a medication while breastfeeding. The most commonly used medications were anti-infectives (15.1 %) and medications for respiratory system (10.9 %). Just over half of mothers stated that they had not received specific advice from their doctor about taking medication while breastfeeding (52.8 %). Pharmacists offered various interventions, such as dispensing a prescribed medication accompanied by breastfeeding counselling (41.8 %), recommending a change to a medication or supplement for safety reasons (15.3 %) and tailored recommendations for monitoring the infant (40.1 %). Pharmacist interventions, including the use of alternative medications/supplements, resulted in a decrease in the frequency of high-risk medications (from 1 % to 0.3 %, p < 0.001).

Conclusion

Community pharmacists play an important role in the care of breastfeeding mothers. In addition to providing breastfeeding counselling and support, community pharmacists significantly improved the safety of medications taken by using relevant sources of information.

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来源期刊

Midwifery 医学-护理

CiteScore

4.50

自引率

7.40%

发文量

221

审稿时长

13.4 weeks

期刊介绍： Midwifery publishes the latest peer reviewed international research to inform the safety, quality, outcomes and experiences of pregnancy, birth and maternity care for childbearing women, their babies and families. The journal’s publications support midwives and maternity care providers to explore and develop their knowledge, skills and attitudes informed by best available evidence. Midwifery provides an international, interdisciplinary forum for the publication, dissemination and discussion of advances in evidence, controversies and current research, and promotes continuing education through publication of systematic and other scholarly reviews and updates. Midwifery articles cover the cultural, clinical, psycho-social, sociological, epidemiological, education, managerial, workforce, organizational and technological areas of practice in preconception, maternal and infant care. The journal welcomes the highest quality scholarly research that employs rigorous methodology. Midwifery is a leading international journal in midwifery and maternal health with a current impact factor of 1.861 (© Thomson Reuters Journal Citation Reports 2016) and employs a double-blind peer review process.