{"title":"保存:增加可变翻转角激励横向松弛优化核磁共振波谱。","authors":"Bernhard Brutscher","doi":"10.5194/mr-5-131-2024","DOIUrl":null,"url":null,"abstract":"<p><p>We introduce the \"Polarization Restoring Excitation SEquence foR Versatile Experiments\" (PRESERVE) pulse sequence element, allowing variable flip-angle adjustment in 2D <math><msup><mi></mi> <mn>1</mn></msup> </math> H- <math><msup><mi></mi> <mn>15</mn></msup> </math> N and <math><msup><mi></mi> <mn>1</mn></msup> </math> H- <math><msup><mi></mi> <mn>13</mn></msup> </math> C transverse-relaxation-optimized-spectroscopy (TROSY)-type correlation experiments. PRESERVE-TROSY exploits a remarkable array of up to nine orthogonal coherence-transfer pathways, showcasing the remarkable potential of spin manipulations achievable through the design and optimization of nuclear magnetic resonance (NMR) pulse sequences.</p>","PeriodicalId":93333,"journal":{"name":"Magnetic resonance (Gottingen, Germany)","volume":"5 2","pages":"131-142"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178132/pdf/","citationCount":"0","resultStr":"{\"title\":\"PRESERVE: adding variable flip-angle excitation to transverse relaxation-optimized NMR spectroscopy.\",\"authors\":\"Bernhard Brutscher\",\"doi\":\"10.5194/mr-5-131-2024\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We introduce the \\\"Polarization Restoring Excitation SEquence foR Versatile Experiments\\\" (PRESERVE) pulse sequence element, allowing variable flip-angle adjustment in 2D <math><msup><mi></mi> <mn>1</mn></msup> </math> H- <math><msup><mi></mi> <mn>15</mn></msup> </math> N and <math><msup><mi></mi> <mn>1</mn></msup> </math> H- <math><msup><mi></mi> <mn>13</mn></msup> </math> C transverse-relaxation-optimized-spectroscopy (TROSY)-type correlation experiments. PRESERVE-TROSY exploits a remarkable array of up to nine orthogonal coherence-transfer pathways, showcasing the remarkable potential of spin manipulations achievable through the design and optimization of nuclear magnetic resonance (NMR) pulse sequences.</p>\",\"PeriodicalId\":93333,\"journal\":{\"name\":\"Magnetic resonance (Gottingen, Germany)\",\"volume\":\"5 2\",\"pages\":\"131-142\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178132/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Magnetic resonance (Gottingen, Germany)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5194/mr-5-131-2024\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"Physics and Astronomy\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Magnetic resonance (Gottingen, Germany)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5194/mr-5-131-2024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Physics and Astronomy","Score":null,"Total":0}
PRESERVE: adding variable flip-angle excitation to transverse relaxation-optimized NMR spectroscopy.
We introduce the "Polarization Restoring Excitation SEquence foR Versatile Experiments" (PRESERVE) pulse sequence element, allowing variable flip-angle adjustment in 2D H- N and H- C transverse-relaxation-optimized-spectroscopy (TROSY)-type correlation experiments. PRESERVE-TROSY exploits a remarkable array of up to nine orthogonal coherence-transfer pathways, showcasing the remarkable potential of spin manipulations achievable through the design and optimization of nuclear magnetic resonance (NMR) pulse sequences.