Tong Ding MD, PhD, Yichen Gong MD, Yuanhao Fu MD, Zhongqi Cui MD, Song Wu MD, Wei Yang MD, Hang Yang MD, Hong Zhao MD, Haibo Feng MD, Huiping Zheng MD, Luyu Meng MD, Rui Guo MD, Huijin Han BS, Yunpeng Ling MD
{"title":"微创冠状动脉旁路移植术治疗多支冠状动脉疾病：一项单中心前瞻性先导研究","authors":"Tong Ding MD, PhD, Yichen Gong MD, Yuanhao Fu MD, Zhongqi Cui MD, Song Wu MD, Wei Yang MD, Hang Yang MD, Hong Zhao MD, Haibo Feng MD, Huiping Zheng MD, Luyu Meng MD, Rui Guo MD, Huijin Han BS, Yunpeng Ling MD","doi":"10.1016/j.xjon.2025.03.030","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>The study sought to explore the characteristics and outcomes of patients undergoing clinically indicated minimally invasive cardiac surgery—coronary artery bypass grafting (MICS-CABG) and off-pump coronary artery bypass for MICS-CABG eligible multivessel disease, to inform the design of a confirmatory comparative effectiveness trial.</div></div><div><h3>Methods</h3><div>Over 30 months, 245 MICS-CABG and 158 off-pump coronary artery bypass participants were enrolled. Health-related quality-of-life was assessed using the 36-Item Short-Form Health Survey and Seattle Angina Questionnaire. The primary end point was the score on the physical component summary and mental component summary subscale of the 36-Item Short-Form Health Survey (on which scores range from 0 to 100, with higher scores indicating better health status).</div></div><div><h3>Results</h3><div>The score on the Physical Component Summary-United States subscale of the 36-Item Short-Form Health Survey increased to a greater extent with MICS-CABG than with off-pump coronary artery bypass at both 7 and 30 days (<em>P</em> = .002 and <em>P</em> = .001, respectively), as well as Physical Component Summary-Hong Kong subscale (MICS-CABG and off-pump coronary artery bypass: <em>P</em> = .002 and <em>P</em> < .001, respectively). The mental component summary subscale of the 36-Item Short-Form Health Survey in either the United States or Hong Kong and all 5 domains of Seattle Angina Questionnaire score were similar between the 2 groups throughout the follow-up period.</div></div><div><h3>Conclusions</h3><div>MICS-CABG, an emerging modality for treating multivessel coronary disease, yields an improved 7- and 30-day physical function than off-pump coronary artery bypass. Moreover, both strategies resulted in similar significant relief from angina over 12 months. A randomized controlled trial is warranted to compare the efficacy of these 2 revascularization strategies. (Prospective Cohort Study on Minimal Invasive Coronary Surgery: NCT04267835).</div></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"25 ","pages":"Pages 96-119"},"PeriodicalIF":1.9000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Minimally invasive coronary bypass grafting for treating multivessel coronary disease: A single-center prospective pilot study\",\"authors\":\"Tong Ding MD, PhD, Yichen Gong MD, Yuanhao Fu MD, Zhongqi Cui MD, Song Wu MD, Wei Yang MD, Hang Yang MD, Hong Zhao MD, Haibo Feng MD, Huiping Zheng MD, Luyu Meng MD, Rui Guo MD, Huijin Han BS, Yunpeng Ling MD\",\"doi\":\"10.1016/j.xjon.2025.03.030\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><div>The study sought to explore the characteristics and outcomes of patients undergoing clinically indicated minimally invasive cardiac surgery—coronary artery bypass grafting (MICS-CABG) and off-pump coronary artery bypass for MICS-CABG eligible multivessel disease, to inform the design of a confirmatory comparative effectiveness trial.</div></div><div><h3>Methods</h3><div>Over 30 months, 245 MICS-CABG and 158 off-pump coronary artery bypass participants were enrolled. Health-related quality-of-life was assessed using the 36-Item Short-Form Health Survey and Seattle Angina Questionnaire. The primary end point was the score on the physical component summary and mental component summary subscale of the 36-Item Short-Form Health Survey (on which scores range from 0 to 100, with higher scores indicating better health status).</div></div><div><h3>Results</h3><div>The score on the Physical Component Summary-United States subscale of the 36-Item Short-Form Health Survey increased to a greater extent with MICS-CABG than with off-pump coronary artery bypass at both 7 and 30 days (<em>P</em> = .002 and <em>P</em> = .001, respectively), as well as Physical Component Summary-Hong Kong subscale (MICS-CABG and off-pump coronary artery bypass: <em>P</em> = .002 and <em>P</em> < .001, respectively). The mental component summary subscale of the 36-Item Short-Form Health Survey in either the United States or Hong Kong and all 5 domains of Seattle Angina Questionnaire score were similar between the 2 groups throughout the follow-up period.</div></div><div><h3>Conclusions</h3><div>MICS-CABG, an emerging modality for treating multivessel coronary disease, yields an improved 7- and 30-day physical function than off-pump coronary artery bypass. Moreover, both strategies resulted in similar significant relief from angina over 12 months. A randomized controlled trial is warranted to compare the efficacy of these 2 revascularization strategies. (Prospective Cohort Study on Minimal Invasive Coronary Surgery: NCT04267835).</div></div>\",\"PeriodicalId\":74032,\"journal\":{\"name\":\"JTCVS open\",\"volume\":\"25 \",\"pages\":\"Pages 96-119\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JTCVS open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666273625001317\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JTCVS open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666273625001317","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Minimally invasive coronary bypass grafting for treating multivessel coronary disease: A single-center prospective pilot study
Objectives
The study sought to explore the characteristics and outcomes of patients undergoing clinically indicated minimally invasive cardiac surgery—coronary artery bypass grafting (MICS-CABG) and off-pump coronary artery bypass for MICS-CABG eligible multivessel disease, to inform the design of a confirmatory comparative effectiveness trial.
Methods
Over 30 months, 245 MICS-CABG and 158 off-pump coronary artery bypass participants were enrolled. Health-related quality-of-life was assessed using the 36-Item Short-Form Health Survey and Seattle Angina Questionnaire. The primary end point was the score on the physical component summary and mental component summary subscale of the 36-Item Short-Form Health Survey (on which scores range from 0 to 100, with higher scores indicating better health status).
Results
The score on the Physical Component Summary-United States subscale of the 36-Item Short-Form Health Survey increased to a greater extent with MICS-CABG than with off-pump coronary artery bypass at both 7 and 30 days (P = .002 and P = .001, respectively), as well as Physical Component Summary-Hong Kong subscale (MICS-CABG and off-pump coronary artery bypass: P = .002 and P < .001, respectively). The mental component summary subscale of the 36-Item Short-Form Health Survey in either the United States or Hong Kong and all 5 domains of Seattle Angina Questionnaire score were similar between the 2 groups throughout the follow-up period.
Conclusions
MICS-CABG, an emerging modality for treating multivessel coronary disease, yields an improved 7- and 30-day physical function than off-pump coronary artery bypass. Moreover, both strategies resulted in similar significant relief from angina over 12 months. A randomized controlled trial is warranted to compare the efficacy of these 2 revascularization strategies. (Prospective Cohort Study on Minimal Invasive Coronary Surgery: NCT04267835).
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
