心率通知检测心脏事件使用卡尔曼滤波器

IF 6.3 2区 医学 Q1 BIOLOGY
Onur Selim Kilic , Afra Nawar , Cem Okan Yaldiz , Farhan Rahman , Chen Chuoqi , Amit Shah , Omer T. Inan
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引用次数: 0

摘要

心脏事件的准确检测可以提高心血管监测和诊断能力。具体来说,检测与主动脉瓣打开(AO)和关闭(AC)相关的基准点有助于提取重要的心室功能信息的时间特征。地震心动图(SCG)提供了一种无创的方法来观察这些机械心脏活动;然而,来自运动或语音伪影的噪声通常会损害这些基点的可靠检测,特别是在压力测试条件下。运动等压力源在决定心血管健康方面至关重要,因为它们可以揭示在休息时不明显的异常。对于心力衰竭这样的疾病尤其如此,在压力下,心功能可能会显著恶化。SCG为无创监测这些机械变化提供了有价值的工具。压力测试结合SCG可能有助于识别心力衰竭的早期迹象。在本研究中,我们提出了一种基于卡尔曼滤波器的方法,称为心率通知卡尔曼滤波器(HIKAF),该方法利用心率(HR)使用SCG稳健地识别AO和AC,即使在中等噪声条件下也是如此。我们通过各种生理状态的结构化实验比较了其与现有方法的有效性。HIKAF与人工标注实现了显著的相关性,基线和练习阶段之间AO点和AC点的相对位移的Pearson’s r值分别为0.934和0.899,大大优于现有算法。这些结果表明,HIKAF能够有效地适应心脏机械事件的动态变化,并在噪声条件下保持鲁棒性,为改善可穿戴设备、远程设置和临床应用中的实时心血管监测提供了有希望的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Heart rate informed detection of cardiac events using the Kalman filter
Accurate detection of cardiac events can improve cardiovascular monitoring and diagnostics capabilities. Specifically, detecting the fiducial points related to aortic valve opening (AO) and closure (AC) facilitates the extraction of important timing characteristics that are informative of ventricular performance. Seismocardiography (SCG) offers a noninvasive way to observe these mechanical cardiac activities; however, noise from motion or speech artifacts often compromises the reliable detection of these fiducial points, especially during stress testing conditions. Stressors such as exercise are critical in determining cardiovascular health, as they can reveal abnormalities not apparent at rest. This is particularly true for conditions like heart failure, where cardiac function may deteriorate significantly under stress. SCG provides a valuable tool to noninvasively monitor these mechanical changes. Stress testing combined with SCG may help identify early signs of heart failure. In this study, we propose a Kalman filter-based methodology, named Heart Rate Informed Kalman Filter (HIKAF), that leverages heart rate (HR) to robustly identify AO and AC using SCG, even under moderately noisy conditions. We compare its effectiveness against existing approaches through structured experiments across various physiological states. HIKAF achieves significant correlations with manual annotations, yielding Pearson’s r values of 0.934 and 0.899 for the relative shifts in AO and AC points between the baseline and exercise stages, substantially outperforming existing algorithms. These results highlight that HIKAF adapts effectively to dynamic changes in cardiac mechanical events and remains robust under noisy conditions, offering promising potential to improve real-time cardiovascular monitoring in wearable devices, remote settings, and clinical applications.
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来源期刊
Computers in biology and medicine
Computers in biology and medicine 工程技术-工程:生物医学
CiteScore
11.70
自引率
10.40%
发文量
1086
审稿时长
74 days
期刊介绍: Computers in Biology and Medicine is an international forum for sharing groundbreaking advancements in the use of computers in bioscience and medicine. This journal serves as a medium for communicating essential research, instruction, ideas, and information regarding the rapidly evolving field of computer applications in these domains. By encouraging the exchange of knowledge, we aim to facilitate progress and innovation in the utilization of computers in biology and medicine.
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