开拓创新,与时俱进:建立、保留和扩展图像分析专业知识。

IF 3.9 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Frontiers in bioinformatics Pub Date : 2025-05-30 eCollection Date: 2025-01-01 DOI:10.3389/fbinf.2025.1613866
David Kirchenbuechler, Mariana De Niz, Constadina Arvanitis
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引用次数: 0

摘要

科学研究越来越复杂,涉及许多不同的实验方法和技术的量化。然而,对于任何一个科学家个人来说,在大范围的科学工具中建立和保持足够的专业知识和能力是具有挑战性的。深厚的专业知识对严谨性和可重复性至关重要;然而,专注的专业知识很容易成为跨学科科学的障碍。在显微镜和图像分析方面尤其如此。核心设施通常可以弥补这一差距,作为尖端技术专业知识的接入点,同时促进协作。我们通过这篇透视文章的目的是与其他显微镜核心设施主管和图像分析师分享我们的经验,他们的目标是将图像分析培训作为一种服务。我们希望这些分享的经验可以帮助其他人通过我们的经验教训来优化他们的服务,并避免我们在Core时间表中遇到的陷阱。在本文中,我们探讨了在西北大学高级显微镜中心建立和扩展图像分析至关重要的三个要素。首先是承诺提供专门的图像分析服务。第二是为当地科学界建立图像分析培训计划,这有助于将分析整合到显微镜工作流程中。第三是与国际货币基金组织等国际组织开展合作。这些组织促进合作,最终导致在整个社区中富有成效地传播新工具。这三个要素对于最大限度地发挥基于成像的科学研究的潜力并最终确保平等获得图像信息学至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Trail-blazing and keeping pace: building, retaining and expanding image analysis expertise.

Trail-blazing and keeping pace: building, retaining and expanding image analysis expertise.

Trail-blazing and keeping pace: building, retaining and expanding image analysis expertise.

Scientific studies are increasingly complex, involving quantification of many different experimental approaches and technologies. However, it is challenging for any individual scientist to build and retain sufficient expertise and competency in a large range of scientific tools. A deep expertise is critical for rigor and reproducibility; however, focused expertise can easily become a hindrance to inter-disciplinary science. This is particularly true with respect to microscopy and image analysis. Core facilities often bridge this gap, serving as an access point to expertise in cutting-edge technologies while facilitating collaboration. Our purpose with this perspective piece is to share our experience with other Microscopy Core Facility Directors and Image analysts who are aiming to establish image analysis training as a service. We hope that this shared experience can help others optimize their service though our lessons learned, and avoid pitfalls we faced during our Core's timeline. In this paper we explore three elements that have been vital for the establishment and expansion of image analysis at the Center for Advanced Microscopy at Northwestern University. The first is a commitment to dedicated image analysis service. The second is establishing image analysis training programs for the local scientific community, which facilitates integration of analysis into microscopy workflows. The third is engagement with international organizations such as BINA. These organization foster collaborations which ultimately result in the fruitful dissemination of novel tools across the community. These three elements are essential to maximize the potential of imaging-based scientific research and ultimately ensuring equal access to image informatics.

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