膝关节周围巨细胞瘤扩展刮除及三明治技术重建的功能效果。

Kevin Jose, Joe Joseph Cherian, Jerin Jeevo, Anoop Pilar, Rinju Krishnan, Mevin Mathew Nedumparambil
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引用次数: 0

摘要

巨细胞瘤(GCT)是一种良性但局部侵袭性的肿瘤。治疗的主要目的是完全消除肿瘤,重建缺损,恢复肢体功能。已经提出了许多手术治疗方案,从更激烈的干预措施,如整体切除,到微创技术,如刮除或刮除结合植骨。尽管大量的出版物关注于巨细胞肿瘤的治愈率、复发率和其他手术考虑因素,但关于巨细胞肿瘤治疗后功能结果的研究有限。病例报告:年龄在20-40岁的个体是典型的GCT患者。患者通常在休息或睡眠时表现出疼痛,在某些情况下,也可能出现病理性骨折。所有患者均进行了临床评估,术前进行了膝关节平片、胸部x线、计算机断层扫描和磁共振成像。所有患者术前均行活检以确定肿瘤的组织学分级并确认诊断。结论:夹心技术是膝关节周围GCT的一种合适的重建方法,包括使用聚甲基丙烯酸甲酯占据刮除后的残留腔,在软骨下区域放置结构性同种异体移植物,并在中间空间应用凝胶形式。它还具有较少的并发症,良好的存活率和积极的功能预后。这种方法保留了骨水泥的优点,减轻了潜在的并发症,并恢复了软骨下骨。我们的病人没有出现任何关节塌陷,复发,免疫并发症。术后1年肢体功能状况良好。因此,基于我们良好的研究结果,我们提倡在膝关节周围的gct中使用这种技术来挽救关节。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Functional Outcome of Extended Curettage and Reconstruction using Sandwich Technique for Giant Cell Tumor around Knee.

Introduction: Giant cell tumors (GCT) are benign yet locally aggressive neoplasms. The primary objectives of treatment are to entirely eliminate the tumor, rebuild the defect, and restore limb functionality. Numerous surgical treatment options have been proposed, ranging from more drastic interventions, such as en bloc excision, to less invasive techniques such as curettage or curettage combined with bone grafting. Limited research addresses the functional outcomes following treatment for giant cell tumors, despite the abundance of publications focusing on cure rates, recurrence, and other surgical considerations of the condition.

Case report: Individuals aged 20-40 are typically the ones affected with GCT. Patients typically exhibit pain during rest or sleep, and in certain instances, may also experience pathologic fractures.All patients were clinically evaluated, plain X-ray of the knee, chest X-ray, computed tomography , and magnetic resonance imaging were taken before the procedure. In all patients a pre-operative, biopsy was performed to determine the tumor's histological grade and to confirm the diagnosis.

Conclusion: The sandwich technique is an appropriate reconstructive procedure for GCT around the knee joint, involving the use of polymethylmethacrylate to occupy the residual cavity post-curettage, the placement of a structural allograft in the subchondral region, and the application of a gel form in the intervening space.It also has less complications, favorable survival rates, and positive functional outcomes. This approach preserves the advantages of cementing, mitigates potential complications, and restores the subchondral bone stock.None of our patients experienced any collapse of the joint, recurrences, immunological complications. All of them also had good functional status of the limb after 1 year. Thus, based on our good findings, we advocate this technique for joint salvage in GCTs around the knee.

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