{"title":"对比增强计算机断层扫描/磁共振成像对Fontan手术后胃食管静脉曲张的测量是有用的。","authors":"Takanori Suzuki, Kentaro Matsuura, Sayuri Yamabe, Kiyomi Kayama, Tsutomu Shinohara, Keiichi Itatani, Yoshiki Okamoto, Hayato Kawamura, Kei Fujiwara, Yoshihiro Seo, Hiromi Kataoka","doi":"10.1111/hepr.14218","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Liver cirrhosis (LC) is a common complication of Fontan surgery (FS) because of the inherent risk of chronic hepatic congestion, and often leads to gastroesophageal varices (GEVs). However, little is known regarding the factors involved in the development of GEVs in patients following FS.</p><p><strong>Methods: </strong>This study included 50 patients who had undergone FS, and were evaluated for abdominal complications between November 2007 and December 2024 through contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI). The presence of GEVs, mainly esophageal varices (EVs), was determined by the imaging data.</p><p><strong>Results: </strong>The number of the patients who developed GEVs and collateral veins following FS were 12 (24%) and 7 (14%), respectively, as evaluated by imaging. No significant differences were observed between the age, sex, and duration from FS to imaging, and blood biochemistry indices of patients with (n = 12) and without EVs (n = 38). However, collateral veins were more prevalent among patients with EVs compared to those without EVs (p = 0.002). In addition, patients with collateral veins had poor ALBI scores than those lacking collateral veins (p = 0.032).</p><p><strong>Conclusions: </strong>The presence of GEVs following FS could not be predicted by blood biochemical indices and other clinical factors, although EVs were more frequently observed in patients with collateral veins. Contrast-enhanced CT or MRI can be useful for surveying GEVs in patients following FS.</p><p><strong>Trial registration: </strong>The study protocol was approved by the Institutional Review Board of Nagoya City University (approval number: 60-24-0125).</p>","PeriodicalId":12987,"journal":{"name":"Hepatology Research","volume":" ","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Contrast-Enhanced Computed Tomography/Magnetic Resonance Imaging Is Useful for Surveying Gastroesophageal Varices in Patients After Fontan Surgery.\",\"authors\":\"Takanori Suzuki, Kentaro Matsuura, Sayuri Yamabe, Kiyomi Kayama, Tsutomu Shinohara, Keiichi Itatani, Yoshiki Okamoto, Hayato Kawamura, Kei Fujiwara, Yoshihiro Seo, Hiromi Kataoka\",\"doi\":\"10.1111/hepr.14218\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Liver cirrhosis (LC) is a common complication of Fontan surgery (FS) because of the inherent risk of chronic hepatic congestion, and often leads to gastroesophageal varices (GEVs). However, little is known regarding the factors involved in the development of GEVs in patients following FS.</p><p><strong>Methods: </strong>This study included 50 patients who had undergone FS, and were evaluated for abdominal complications between November 2007 and December 2024 through contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI). The presence of GEVs, mainly esophageal varices (EVs), was determined by the imaging data.</p><p><strong>Results: </strong>The number of the patients who developed GEVs and collateral veins following FS were 12 (24%) and 7 (14%), respectively, as evaluated by imaging. No significant differences were observed between the age, sex, and duration from FS to imaging, and blood biochemistry indices of patients with (n = 12) and without EVs (n = 38). However, collateral veins were more prevalent among patients with EVs compared to those without EVs (p = 0.002). In addition, patients with collateral veins had poor ALBI scores than those lacking collateral veins (p = 0.032).</p><p><strong>Conclusions: </strong>The presence of GEVs following FS could not be predicted by blood biochemical indices and other clinical factors, although EVs were more frequently observed in patients with collateral veins. Contrast-enhanced CT or MRI can be useful for surveying GEVs in patients following FS.</p><p><strong>Trial registration: </strong>The study protocol was approved by the Institutional Review Board of Nagoya City University (approval number: 60-24-0125).</p>\",\"PeriodicalId\":12987,\"journal\":{\"name\":\"Hepatology Research\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2025-06-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Hepatology Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/hepr.14218\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hepatology Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/hepr.14218","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Contrast-Enhanced Computed Tomography/Magnetic Resonance Imaging Is Useful for Surveying Gastroesophageal Varices in Patients After Fontan Surgery.
Objectives: Liver cirrhosis (LC) is a common complication of Fontan surgery (FS) because of the inherent risk of chronic hepatic congestion, and often leads to gastroesophageal varices (GEVs). However, little is known regarding the factors involved in the development of GEVs in patients following FS.
Methods: This study included 50 patients who had undergone FS, and were evaluated for abdominal complications between November 2007 and December 2024 through contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI). The presence of GEVs, mainly esophageal varices (EVs), was determined by the imaging data.
Results: The number of the patients who developed GEVs and collateral veins following FS were 12 (24%) and 7 (14%), respectively, as evaluated by imaging. No significant differences were observed between the age, sex, and duration from FS to imaging, and blood biochemistry indices of patients with (n = 12) and without EVs (n = 38). However, collateral veins were more prevalent among patients with EVs compared to those without EVs (p = 0.002). In addition, patients with collateral veins had poor ALBI scores than those lacking collateral veins (p = 0.032).
Conclusions: The presence of GEVs following FS could not be predicted by blood biochemical indices and other clinical factors, although EVs were more frequently observed in patients with collateral veins. Contrast-enhanced CT or MRI can be useful for surveying GEVs in patients following FS.
Trial registration: The study protocol was approved by the Institutional Review Board of Nagoya City University (approval number: 60-24-0125).
期刊介绍：
Hepatology Research (formerly International Hepatology Communications) is the official journal of the Japan Society of Hepatology, and publishes original articles, reviews and short comunications dealing with hepatology. Reviews or mini-reviews are especially welcomed from those areas within hepatology undergoing rapid changes. Short communications should contain concise definitive information.
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