肾移植受者肺动脉瓣肿块。

IF 2.3 4区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiovascular Pathology Pub Date : 2025-06-13 DOI:10.1016/j.carpath.2025.107745

Ilyse Darwish, Benoît de Varennes, Pierre Olivier Fiset, Sophie Camilleri-Broët, Vynka Lash, Marcelo Cantarovich, Todd C Lee, Cecilia T Costiniuk

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引用次数: 0

摘要

一例43岁女性肾移植患者表现为疲劳、呼吸困难、贫血和血小板减少。胸部CT显示肺结节，经胸超声心动图发现肺动脉瓣附着一个大的、多分叶的、多囊性肿块。病理证实有真菌菌丝，支气管肺泡灌洗液中有烟曲霉生长，血清半乳甘露聚糖曲霉抗原指数为1.95。切除肺动脉瓣，置入生物假体瓣膜。病人用伏立康唑治疗。肺动脉瓣曲霉菌性心内膜炎（AE）是一种罕见的疾病，死亡率高。鉴于移植受者人数的增加，在这一人群中提高临床警惕是有必要的。

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A renal transplant recipient with a pulmonic valve mass.

A 43-year-old female with a renal transplant presented with fatigue, dyspnea, anemia, and thrombocytopenia. Chest CT revealed pulmonary nodules, and transthoracic echocardiography identified a large, multi-lobulated, multi-cystic mass attached to the pulmonic valve. Pathology demonstrated fungal hyphae, and bronchoalveolar lavage (BAL) fluid grew Aspergillus fumigatus, with a serum Aspergillus galactomannan (GM) antigen index of 1.95. The pulmonic valve was excised and a bioprosthetic valve was inserted. The patient was treated with voriconazole. Pulmonic valve Aspergillus endocarditis (AE) is a rare condition associated with high mortality. Given the rising number of transplant recipients, heightened clinical vigilance is warranted in this population.

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来源期刊

Cardiovascular Pathology 医学-病理学

CiteScore

7.50

自引率

2.70%

发文量

审稿时长

18 days

期刊介绍： Cardiovascular Pathology is a bimonthly journal that presents articles on topics covering the entire spectrum of cardiovascular disease. The Journal''s primary objective is to publish papers on disease-oriented morphology and pathogenesis from clinicians and scientists in the cardiovascular field. Subjects covered include cardiovascular biology, prosthetic devices, molecular biology and experimental models of cardiovascular disease.