便携式超低场MRI在急性脑卒中护理中的应用：一项初步研究。

IF 4.5 3区医学 Q1 CLINICAL NEUROLOGY

European Stroke Journal Pub Date : 2025-06-13 DOI:10.1177/23969873251344761

Niklas M von Danwitz, Nils C Lehnen, Julius N Meißner, Omid Shirvani Samani, Hannah Asperger, Christian Thielscher, Taraneh Ebrahimi, Julia Layer, Louisa Nitsch, Franziska Dorn, Alexander Radbruch, Felix J Bode, Johannes M Weller, Anne Groteklaes, Gabor C Petzold, Hemmen Sabir, Sebastian Stösser

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引用次数: 0

摘要

神经影像学是治疗脑卒中患者的先决条件，但它并不是在全球范围内可用的。便携式超低场（pULF） MRI有潜力改善神经成像，从而在全球范围内治疗中风。在一项试点研究中，我们首次在欧洲三级卒中中心使用pULF-MRI，并将其与高场（HF） MRI进行比较，评估其诊断价值。患者和方法：连续入院的疑似缺血性卒中患者除标准成像外，还使用0.064 Tesla Swoop®便携式磁共振成像系统进行pULF-MRI。对HF-MRI和pULF-MRI扫描进行盲法评估，比较基于pULF-MRI和HF-MRI的诊断准确性和基于成像的治疗决策。结果：17例患者行pULF-MRI检查，其中12例在HF-MRI上有缺血性病变。8/12例患者在pULF-MRI上发现缺血性病变。pULF-MRI未发现的4例梗死灶直径均小于6mm。在所有病例中，盲法团队基于pULF-MRI的虚拟治疗决策与实际临床决策相匹配。结论：这项单中心研究表明，pULF-MRI在急性脑卒中护理中是一种很有前途的工具，为治疗决策和随访监测提供可靠的成像。如果HF-MRI无法获得，pULF-MRI可能支持急性卒中治疗，并且在资源有限的情况下可能特别有用。pULF-MRI的局限性包括采集时间长，缺乏血管成像和出血敏感序列。

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Portable ultra-low-field MRI in acute stroke care: A pilot study.

Introduction: Neuroimaging is a prerequisite for treatment of stroke patients, but it is not available all over the globe. Portable ultra-low field (pULF) MRI has the potential to improve access to neuroimaging and thus stroke care worldwide. In a pilot study, we were the first to utilise pULF-MRI in a European tertiary stroke centre and to evaluate its diagnostic value compared to high-field (HF) MRI.

Patients and methods: Consecutive patients admitted for suspected ischaemic stroke underwent pULF-MRI using the 0.064 Tesla Swoop^® portable MR imaging system in addition to standard imaging. HF-MRI and pULF-MRI scans were blindly assessed to compare the diagnostic accuracy and imaging-based therapeutic decisions based on pULF-MRI to HF-MRI.

Results: Seventeen patients underwent pULF-MRI, 12 of whom had ischaemic lesions on HF-MRI. Ischaemic lesions were detected on pULF-MRI in 8/12 cases. The four infarcts not identified on pULF-MRI were all smaller than 6 mm in diameter. In all cases, a virtual treatment decision based on pULF-MRI by a blinded team matched the actual clinical decisions.

Conclusion: This single-centre study demonstrates that pULF-MRI is a promising tool in acute stroke care, providing reliable imaging for treatment decision and follow-up monitoring. pULF-MRI may support acute stroke care if HF-MRI is unavailable and may be particularly helpful in resource-limited settings. Limitations of pULF-MRI include long acquisition times and the lack of vessel imaging and haemorrhage-sensitive sequences.

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来源期刊

European Stroke Journal Multiple-

CiteScore

7.50

自引率

6.60%

发文量

102

期刊介绍： Launched in 2016 the European Stroke Journal (ESJ) is the official journal of the European Stroke Organisation (ESO), a professional non-profit organization with over 1,400 individual members, and affiliations to numerous related national and international societies. ESJ covers clinical stroke research from all fields, including clinical trials, epidemiology, primary and secondary prevention, diagnosis, acute and post-acute management, guidelines, translation of experimental findings into clinical practice, rehabilitation, organisation of stroke care, and societal impact. It is open to authors from all relevant medical and health professions. Article types include review articles, original research, protocols, guidelines, editorials and letters to the Editor. Through ESJ, authors and researchers have gained a new platform for the rapid and professional publication of peer reviewed scientific material of the highest standards; publication in ESJ is highly competitive. The journal and its editorial team has developed excellent cooperation with sister organisations such as the World Stroke Organisation and the International Journal of Stroke, and the American Heart Organization/American Stroke Association and the journal Stroke. ESJ is fully peer-reviewed and is a member of the Committee on Publication Ethics (COPE). Issues are published 4 times a year (March, June, September and December) and articles are published OnlineFirst prior to issue publication.