Michaela Theilmann, Sneha Sarah Mani, Pascal Geldsetzer, Shivani A Patel, Mohammed K Ali, Harsha Thirumurthy, K M Venkat Narayan, Viswanathan Mohan, Nikhil Tandon, Dorairaj Prabhakaran, Nikkil Sudharsanan
{"title":"家庭筛查能改善高血压的诊断、治疗和控制吗?印度城市的回归不连续分析。","authors":"Michaela Theilmann, Sneha Sarah Mani, Pascal Geldsetzer, Shivani A Patel, Mohammed K Ali, Harsha Thirumurthy, K M Venkat Narayan, Viswanathan Mohan, Nikhil Tandon, Dorairaj Prabhakaran, Nikkil Sudharsanan","doi":"10.1136/bmjgh-2024-017167","DOIUrl":null,"url":null,"abstract":"<p><p>As part of India's efforts to expand primary healthcare services, several state governments are implementing or considering home-based hypertension screening programmes to improve population-wide diagnosis and blood pressure (BP) control rates. However, there is limited evidence on the effectiveness of home-based screening programmes in India. Using six waves of population-representative cohort data (N=15574), we estimate the causal effect of a home-based hypertension screening intervention on diagnosis, treatment, and BP using a novel application of the Regression Discontinuity Design. We find that measuring individuals' BP in their homes and providing health information and a referral to those with elevated BP did not meaningfully improve hypertension diagnosis (0.12 percentage points (pp), 95% CI -1.39 to 1.75), treatment (-0.16 pp, 95% CI -2.18 to 1.03), or change in BP (systolic: -0.96mm Hg, 95% CI -5.63 to 1.14; diastolic: 0.21, 95% CI -1.65 to 1.65). Our heterogeneity analyses suggest that home-based screening may reduce systolic BP for women with secondary education and women living in Chennai. However, we find null effects for diagnosis and treatment among these subpopulations and in all outcome variables across the other subpopulations and alternative specifications. Our findings suggest that a lack of knowledge of one's hypertension status might not be the primary reason for low diagnosis and treatment rates in India, where other structural and behavioural barriers may be more relevant. Adapting screening efforts to address these additional barriers will be essential for India's efforts to achieve universal health coverage.</p>","PeriodicalId":9137,"journal":{"name":"BMJ Global Health","volume":"10 6","pages":""},"PeriodicalIF":7.1000,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Does home-based screening improve hypertension diagnosis, treatment and control? A regression discontinuity analysis in urban India.\",\"authors\":\"Michaela Theilmann, Sneha Sarah Mani, Pascal Geldsetzer, Shivani A Patel, Mohammed K Ali, Harsha Thirumurthy, K M Venkat Narayan, Viswanathan Mohan, Nikhil Tandon, Dorairaj Prabhakaran, Nikkil Sudharsanan\",\"doi\":\"10.1136/bmjgh-2024-017167\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>As part of India's efforts to expand primary healthcare services, several state governments are implementing or considering home-based hypertension screening programmes to improve population-wide diagnosis and blood pressure (BP) control rates. However, there is limited evidence on the effectiveness of home-based screening programmes in India. Using six waves of population-representative cohort data (N=15574), we estimate the causal effect of a home-based hypertension screening intervention on diagnosis, treatment, and BP using a novel application of the Regression Discontinuity Design. We find that measuring individuals' BP in their homes and providing health information and a referral to those with elevated BP did not meaningfully improve hypertension diagnosis (0.12 percentage points (pp), 95% CI -1.39 to 1.75), treatment (-0.16 pp, 95% CI -2.18 to 1.03), or change in BP (systolic: -0.96mm Hg, 95% CI -5.63 to 1.14; diastolic: 0.21, 95% CI -1.65 to 1.65). Our heterogeneity analyses suggest that home-based screening may reduce systolic BP for women with secondary education and women living in Chennai. However, we find null effects for diagnosis and treatment among these subpopulations and in all outcome variables across the other subpopulations and alternative specifications. Our findings suggest that a lack of knowledge of one's hypertension status might not be the primary reason for low diagnosis and treatment rates in India, where other structural and behavioural barriers may be more relevant. Adapting screening efforts to address these additional barriers will be essential for India's efforts to achieve universal health coverage.</p>\",\"PeriodicalId\":9137,\"journal\":{\"name\":\"BMJ Global Health\",\"volume\":\"10 6\",\"pages\":\"\"},\"PeriodicalIF\":7.1000,\"publicationDate\":\"2025-06-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMJ Global Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1136/bmjgh-2024-017167\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMJ Global Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1136/bmjgh-2024-017167","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
摘要
作为印度扩大初级卫生保健服务努力的一部分,一些邦政府正在实施或考虑以家庭为基础的高血压筛查计划,以提高全民诊断和血压控制率。然而,关于印度家庭筛查方案有效性的证据有限。使用六波具有人口代表性的队列数据(N=15574),我们使用回归不连续设计的新应用估计了以家庭为基础的高血压筛查干预对诊断、治疗和血压的因果效应。我们发现,在家中测量个体血压、提供健康信息并向血压升高的患者转诊并不能显著改善高血压诊断(0.12个百分点,95% CI -1.39至1.75)、治疗(-0.16个百分点,95% CI -2.18至1.03)或血压变化(收缩压:-0.96mm Hg, 95% CI -5.63至1.14;舒张期:0.21,95% CI -1.65 ~ 1.65)。我们的异质性分析表明,家庭筛查可以降低中等教育程度的妇女和居住在金奈的妇女的收缩压。然而,我们发现在这些亚群中诊断和治疗无效,在其他亚群和替代规范的所有结果变量中无效。我们的研究结果表明,缺乏对高血压状况的了解可能不是印度低诊断率和治疗率的主要原因,其他结构和行为障碍可能更相关。调整筛查工作以解决这些额外障碍,对印度实现全民健康覆盖的努力至关重要。
Does home-based screening improve hypertension diagnosis, treatment and control? A regression discontinuity analysis in urban India.
As part of India's efforts to expand primary healthcare services, several state governments are implementing or considering home-based hypertension screening programmes to improve population-wide diagnosis and blood pressure (BP) control rates. However, there is limited evidence on the effectiveness of home-based screening programmes in India. Using six waves of population-representative cohort data (N=15574), we estimate the causal effect of a home-based hypertension screening intervention on diagnosis, treatment, and BP using a novel application of the Regression Discontinuity Design. We find that measuring individuals' BP in their homes and providing health information and a referral to those with elevated BP did not meaningfully improve hypertension diagnosis (0.12 percentage points (pp), 95% CI -1.39 to 1.75), treatment (-0.16 pp, 95% CI -2.18 to 1.03), or change in BP (systolic: -0.96mm Hg, 95% CI -5.63 to 1.14; diastolic: 0.21, 95% CI -1.65 to 1.65). Our heterogeneity analyses suggest that home-based screening may reduce systolic BP for women with secondary education and women living in Chennai. However, we find null effects for diagnosis and treatment among these subpopulations and in all outcome variables across the other subpopulations and alternative specifications. Our findings suggest that a lack of knowledge of one's hypertension status might not be the primary reason for low diagnosis and treatment rates in India, where other structural and behavioural barriers may be more relevant. Adapting screening efforts to address these additional barriers will be essential for India's efforts to achieve universal health coverage.
期刊介绍:
BMJ Global Health is an online Open Access journal from BMJ that focuses on publishing high-quality peer-reviewed content pertinent to individuals engaged in global health, including policy makers, funders, researchers, clinicians, and frontline healthcare workers. The journal encompasses all facets of global health, with a special emphasis on submissions addressing underfunded areas such as non-communicable diseases (NCDs). It welcomes research across all study phases and designs, from study protocols to phase I trials to meta-analyses, including small or specialized studies. The journal also encourages opinionated discussions on controversial topics.