{"title":"心血管疾病代谢重编程的文献计量学和可视化分析：2000年至2024年的趋势、关键因素和未来方向。","authors":"Xing Chen, Liu Lin Yang, Li Xiang Li, Yan Deng","doi":"10.2174/011573403X371021250109064231","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Metabolic reprogramming is critical in cardiovascular disease (CVD) research, affecting a variety of diseases such as myocardial damage, coronary heart disease, and atherosclerosis, and has also emerged as a therapeutic target. This study conducts a bibliometric analysis of the past 24 years to identify trends and hotspots in CVD metabolism, aiming to guide future research and inform policy.</p><p><strong>Methods: </strong>This study analyzes publications from January 1, 2000, to October 10, 2024, using the Web of Science Core Collection database. Tools like CiteSpace, VOSviewer, and SCImago Graphica were used for co-authorship, keyword, citation, and journal visualizations. Dual-map overlays and annual publication trends were examined to uncover hotspots, trends, and the progression of metabolic reprogramming in CVD.</p><p><strong>Results: </strong>This study analyzed 765 articles and reviews from 66 countries. The USA had the most publications, with the University of Milan being the most productive institution. Després, JP's team in Italy, published the most papers. The International Journal of Molecular Sciences had the highest publication count, while Cardiovascular Diabetology had the greatest citation impact. Recent research has mainly focused on the role of immune cell substrate metabolism in CVD.</p><p><strong>Conclusion: </strong>This study reveals the development trend and research characteristics of CVD metabolic reprogramming over the past 24 years, from the early focus on disease risk factors to the recent exploration of the transformation of immune cell metabolism. In the future, targeting immune cell metabolism will drive CVD therapy forward.</p>","PeriodicalId":10832,"journal":{"name":"Current Cardiology Reviews","volume":"21 4","pages":"e1573403X371021"},"PeriodicalIF":2.4000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180361/pdf/","citationCount":"0","resultStr":"{\"title\":\"A Bibliometric and Visualization Analysis of Metabolic Reprogramming in Cardiovascular Diseases: Trends, Key Contributors, and Future Directions from 2000 to 2024.\",\"authors\":\"Xing Chen, Liu Lin Yang, Li Xiang Li, Yan Deng\",\"doi\":\"10.2174/011573403X371021250109064231\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Metabolic reprogramming is critical in cardiovascular disease (CVD) research, affecting a variety of diseases such as myocardial damage, coronary heart disease, and atherosclerosis, and has also emerged as a therapeutic target. 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The International Journal of Molecular Sciences had the highest publication count, while Cardiovascular Diabetology had the greatest citation impact. Recent research has mainly focused on the role of immune cell substrate metabolism in CVD.</p><p><strong>Conclusion: </strong>This study reveals the development trend and research characteristics of CVD metabolic reprogramming over the past 24 years, from the early focus on disease risk factors to the recent exploration of the transformation of immune cell metabolism. In the future, targeting immune cell metabolism will drive CVD therapy forward.</p>\",\"PeriodicalId\":10832,\"journal\":{\"name\":\"Current Cardiology Reviews\",\"volume\":\"21 4\",\"pages\":\"e1573403X371021\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180361/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Cardiology Reviews\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/011573403X371021250109064231\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Cardiology Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/011573403X371021250109064231","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
摘要
背景：代谢重编程在心血管疾病（CVD）研究中至关重要，影响心肌损伤、冠心病和动脉粥样硬化等多种疾病，也已成为治疗靶点。本研究通过对过去24年的文献计量分析，确定心血管疾病代谢的趋势和热点，旨在指导未来的研究和政策。方法：本研究使用Web of Science Core Collection数据库，分析2000年1月1日至2024年10月10日的出版物。CiteSpace、VOSviewer和SCImago Graphica等工具被用于共同作者、关键字、引文和期刊可视化。双图叠加和年度出版物趋势进行了检查，以揭示心血管疾病代谢重编程的热点、趋势和进展。结果：本研究分析了来自66个国家的765篇文章和综述。美国拥有最多的出版物，米兰大学是最具生产力的机构。JP在意大利的团队despracims发表的论文最多。《国际分子科学杂志》（International Journal of Molecular Sciences）的发表数量最高，而《心血管糖尿病学》（Cardiovascular diabetes ology）的引用影响最大。近年来的研究主要集中在免疫细胞底物代谢在心血管疾病中的作用。结论：本研究揭示了近24年来CVD代谢重编程的发展趋势和研究特点，从早期对疾病危险因素的关注到近期对免疫细胞代谢转化的探索。未来，靶向免疫细胞代谢将推动心血管疾病治疗向前发展。
A Bibliometric and Visualization Analysis of Metabolic Reprogramming in Cardiovascular Diseases: Trends, Key Contributors, and Future Directions from 2000 to 2024.
Background: Metabolic reprogramming is critical in cardiovascular disease (CVD) research, affecting a variety of diseases such as myocardial damage, coronary heart disease, and atherosclerosis, and has also emerged as a therapeutic target. This study conducts a bibliometric analysis of the past 24 years to identify trends and hotspots in CVD metabolism, aiming to guide future research and inform policy.
Methods: This study analyzes publications from January 1, 2000, to October 10, 2024, using the Web of Science Core Collection database. Tools like CiteSpace, VOSviewer, and SCImago Graphica were used for co-authorship, keyword, citation, and journal visualizations. Dual-map overlays and annual publication trends were examined to uncover hotspots, trends, and the progression of metabolic reprogramming in CVD.
Results: This study analyzed 765 articles and reviews from 66 countries. The USA had the most publications, with the University of Milan being the most productive institution. Després, JP's team in Italy, published the most papers. The International Journal of Molecular Sciences had the highest publication count, while Cardiovascular Diabetology had the greatest citation impact. Recent research has mainly focused on the role of immune cell substrate metabolism in CVD.
Conclusion: This study reveals the development trend and research characteristics of CVD metabolic reprogramming over the past 24 years, from the early focus on disease risk factors to the recent exploration of the transformation of immune cell metabolism. In the future, targeting immune cell metabolism will drive CVD therapy forward.
期刊介绍：
Current Cardiology Reviews publishes frontier reviews of high quality on all the latest advances on the practical and clinical approach to the diagnosis and treatment of cardiovascular disease. All relevant areas are covered by the journal including arrhythmia, congestive heart failure, cardiomyopathy, congenital heart disease, drugs, methodology, pacing, and preventive cardiology. The journal is essential reading for all researchers and clinicians in cardiology.
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