Foroud Aghapour Zangeneh MD , Gonçalo G. Almeida MD , Susanne Bensler MD , Reza Omidi Varmezani MD , Thomas Sartoretti MD , Frank Johannes Ahlhelm MD , Tilo Niemann MD, MHBA, EBCR , André Euler MD, MHBA, EBCR
{"title":"改进的CT波束硬化降低——对急诊脑成像图像质量和诊断确定性的影响。","authors":"Foroud Aghapour Zangeneh MD , Gonçalo G. Almeida MD , Susanne Bensler MD , Reza Omidi Varmezani MD , Thomas Sartoretti MD , Frank Johannes Ahlhelm MD , Tilo Niemann MD, MHBA, EBCR , André Euler MD, MHBA, EBCR","doi":"10.1016/j.acra.2025.05.054","DOIUrl":null,"url":null,"abstract":"<div><h3>Rationale and Objectives</h3><div>To assess the impact of an optimized beam-hardening artifact reduction algorithm on image quality and diagnostic certainty in emergency unenhanced brain CT.</div></div><div><h3>Materials and Methods</h3><div>Retrospective study of consecutive patients referred for unenhanced brain CT to rule out traumatic brain injuries in 2023. Images were reconstructed using both (A) a standard and (B) an optimized iterative beam-hardening correction algorithm (iBHC). CT attenuation, image noise and SNR were measured in the cortex of supratentorial and infratentorial regions and in the pons. Posterior Fossa Artifact Index (PFAI) and Subcalvarial Artifact Index (SAI) were calculated. Two neuroradiologists and two emergency radiologists independently compared artifacts and diagnostic certainty between both algorithms using 5-point Likert scales and side-by-side comparisons. A paired Wilcoxon-test with correction for multiple testing was used.</div></div><div><h3>Results</h3><div>100 consecutive patients (55 women; 64.1 ± 20 years) were included. CT attenuation was significantly lower for B (all P <.0001). SNR was significantly lower supratentorial (frontal region: 10.5 vs. 12.9, P<.0001) and significantly higher in the pons (5.9 vs. 5.5, P <.0001) for B. PFAI was significantly reduced for B (5.5 vs. 6.4, P <.0001), while there was no significant difference in SAI (P = 0.304). The optimized algorithm was selected as superior in 100%, 100%, 99%, 99% of supratentorial and in 100%, 99%, 99%, 86% of infratentorial cases for readers 1 to 4, respectively.</div></div><div><h3>Conclusion</h3><div>An optimized iBHC algorithm demonstrated significantly improved image quality, reduced artifacts and improved diagnostic certainty in emergency unenhanced brain CT.</div></div>","PeriodicalId":50928,"journal":{"name":"Academic Radiology","volume":"32 10","pages":"Pages 6072-6079"},"PeriodicalIF":3.9000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Improved Beam-hardening Reduction in CT - Impact on Image Quality and Diagnostic Certainty in Emergency Imaging of the Brain\",\"authors\":\"Foroud Aghapour Zangeneh MD , Gonçalo G. Almeida MD , Susanne Bensler MD , Reza Omidi Varmezani MD , Thomas Sartoretti MD , Frank Johannes Ahlhelm MD , Tilo Niemann MD, MHBA, EBCR , André Euler MD, MHBA, EBCR\",\"doi\":\"10.1016/j.acra.2025.05.054\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Rationale and Objectives</h3><div>To assess the impact of an optimized beam-hardening artifact reduction algorithm on image quality and diagnostic certainty in emergency unenhanced brain CT.</div></div><div><h3>Materials and Methods</h3><div>Retrospective study of consecutive patients referred for unenhanced brain CT to rule out traumatic brain injuries in 2023. Images were reconstructed using both (A) a standard and (B) an optimized iterative beam-hardening correction algorithm (iBHC). CT attenuation, image noise and SNR were measured in the cortex of supratentorial and infratentorial regions and in the pons. Posterior Fossa Artifact Index (PFAI) and Subcalvarial Artifact Index (SAI) were calculated. Two neuroradiologists and two emergency radiologists independently compared artifacts and diagnostic certainty between both algorithms using 5-point Likert scales and side-by-side comparisons. A paired Wilcoxon-test with correction for multiple testing was used.</div></div><div><h3>Results</h3><div>100 consecutive patients (55 women; 64.1 ± 20 years) were included. CT attenuation was significantly lower for B (all P <.0001). SNR was significantly lower supratentorial (frontal region: 10.5 vs. 12.9, P<.0001) and significantly higher in the pons (5.9 vs. 5.5, P <.0001) for B. PFAI was significantly reduced for B (5.5 vs. 6.4, P <.0001), while there was no significant difference in SAI (P = 0.304). The optimized algorithm was selected as superior in 100%, 100%, 99%, 99% of supratentorial and in 100%, 99%, 99%, 86% of infratentorial cases for readers 1 to 4, respectively.</div></div><div><h3>Conclusion</h3><div>An optimized iBHC algorithm demonstrated significantly improved image quality, reduced artifacts and improved diagnostic certainty in emergency unenhanced brain CT.</div></div>\",\"PeriodicalId\":50928,\"journal\":{\"name\":\"Academic Radiology\",\"volume\":\"32 10\",\"pages\":\"Pages 6072-6079\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Academic Radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1076633225005318\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Academic Radiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1076633225005318","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Improved Beam-hardening Reduction in CT - Impact on Image Quality and Diagnostic Certainty in Emergency Imaging of the Brain
Rationale and Objectives
To assess the impact of an optimized beam-hardening artifact reduction algorithm on image quality and diagnostic certainty in emergency unenhanced brain CT.
Materials and Methods
Retrospective study of consecutive patients referred for unenhanced brain CT to rule out traumatic brain injuries in 2023. Images were reconstructed using both (A) a standard and (B) an optimized iterative beam-hardening correction algorithm (iBHC). CT attenuation, image noise and SNR were measured in the cortex of supratentorial and infratentorial regions and in the pons. Posterior Fossa Artifact Index (PFAI) and Subcalvarial Artifact Index (SAI) were calculated. Two neuroradiologists and two emergency radiologists independently compared artifacts and diagnostic certainty between both algorithms using 5-point Likert scales and side-by-side comparisons. A paired Wilcoxon-test with correction for multiple testing was used.
Results
100 consecutive patients (55 women; 64.1 ± 20 years) were included. CT attenuation was significantly lower for B (all P <.0001). SNR was significantly lower supratentorial (frontal region: 10.5 vs. 12.9, P<.0001) and significantly higher in the pons (5.9 vs. 5.5, P <.0001) for B. PFAI was significantly reduced for B (5.5 vs. 6.4, P <.0001), while there was no significant difference in SAI (P = 0.304). The optimized algorithm was selected as superior in 100%, 100%, 99%, 99% of supratentorial and in 100%, 99%, 99%, 86% of infratentorial cases for readers 1 to 4, respectively.
Conclusion
An optimized iBHC algorithm demonstrated significantly improved image quality, reduced artifacts and improved diagnostic certainty in emergency unenhanced brain CT.
期刊介绍:
Academic Radiology publishes original reports of clinical and laboratory investigations in diagnostic imaging, the diagnostic use of radioactive isotopes, computed tomography, positron emission tomography, magnetic resonance imaging, ultrasound, digital subtraction angiography, image-guided interventions and related techniques. It also includes brief technical reports describing original observations, techniques, and instrumental developments; state-of-the-art reports on clinical issues, new technology and other topics of current medical importance; meta-analyses; scientific studies and opinions on radiologic education; and letters to the Editor.