Sharon E Leong, T K Logan, Christal L Badour, Justin E Karr
{"title":"有亲密伴侣暴力史的女性的多重创伤临床三联征。","authors":"Sharon E Leong, T K Logan, Christal L Badour, Justin E Karr","doi":"10.1089/neu.2025.0064","DOIUrl":null,"url":null,"abstract":"<p><p>Women with a history of intimate partner violence (IPV) are at risk for traumatic brain injury (TBI) with persistent neurobehavioral symptoms, post-traumatic stress disorder (PTSD), and chronic pain, which, together, characterize the polytrauma clinical triad. Among predominantly male Veteran samples, research has suggested that the triad may exacerbate health problems, compared with the presence of any component of the triad alone. The current study is the first to explore the polytrauma clinical triad among a sample of cisgender women who have experienced IPV (<i>N</i> = 198; <i>M</i> = 39.6 years old, <i>SD</i> = 11.9; 83.3% White, 7.1% Hispanic; 59.1% college-educated). Compared with participants without TBI history, participants with IPV-related TBI had higher rates of chronic pain (43.8% vs. 29.0%, <i>p</i> = 0.045, odds ratio [<i>OR</i>] = 1.87 [95% confidence interval: 1.01, 3.43]), PTSD with chronic pain (19.0% vs. 6.5%, <i>p</i> = 0.009, <i>OR</i> = 3.84 [1.41, 10.46]), neurobehavioral symptoms with chronic pain (40.0% vs. 22.6%, <i>p</i> = 0.030, <i>OR</i> = 2.01 [1.07, 3.79]), and the polytrauma clinical triad (19.0% vs. 6.5%, <i>p</i> = 0.009, <i>OR</i> = 3.84 [1.41, 10.46]), after adjusting for age and education. After controlling for IPV severity, however, there were no statistically significant group differences, suggesting that IPV severity may be closely linked to both risk of TBI and elevated symptomatology associated with the polytrauma clinical triad. Additionally, as the number of lifetime TBIs increased, the odds of having chronic pain (<i>p</i> = 0.011, <i>OR</i> = 1.17 [1.04, 1.33]) and chronic pain with concurrent neurobehavioral symptoms (<i>p</i> = 0.007, <i>OR</i> = 1.05 [1.05, 1.34]) also increased. These findings suggest that, especially when comorbid with IPV-related TBI, chronic pain may be a priority treatment target among individuals with a history of IPV. Considering that women with a history of IPV often experience concurrent health conditions, multicomponent interventions that address each condition within the polytrauma clinical triad may benefit this population.</p>","PeriodicalId":16512,"journal":{"name":"Journal of neurotrauma","volume":" ","pages":""},"PeriodicalIF":3.9000,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Polytrauma Clinical Triad Among Women with a History of Intimate Partner Violence.\",\"authors\":\"Sharon E Leong, T K Logan, Christal L Badour, Justin E Karr\",\"doi\":\"10.1089/neu.2025.0064\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Women with a history of intimate partner violence (IPV) are at risk for traumatic brain injury (TBI) with persistent neurobehavioral symptoms, post-traumatic stress disorder (PTSD), and chronic pain, which, together, characterize the polytrauma clinical triad. Among predominantly male Veteran samples, research has suggested that the triad may exacerbate health problems, compared with the presence of any component of the triad alone. The current study is the first to explore the polytrauma clinical triad among a sample of cisgender women who have experienced IPV (<i>N</i> = 198; <i>M</i> = 39.6 years old, <i>SD</i> = 11.9; 83.3% White, 7.1% Hispanic; 59.1% college-educated). Compared with participants without TBI history, participants with IPV-related TBI had higher rates of chronic pain (43.8% vs. 29.0%, <i>p</i> = 0.045, odds ratio [<i>OR</i>] = 1.87 [95% confidence interval: 1.01, 3.43]), PTSD with chronic pain (19.0% vs. 6.5%, <i>p</i> = 0.009, <i>OR</i> = 3.84 [1.41, 10.46]), neurobehavioral symptoms with chronic pain (40.0% vs. 22.6%, <i>p</i> = 0.030, <i>OR</i> = 2.01 [1.07, 3.79]), and the polytrauma clinical triad (19.0% vs. 6.5%, <i>p</i> = 0.009, <i>OR</i> = 3.84 [1.41, 10.46]), after adjusting for age and education. After controlling for IPV severity, however, there were no statistically significant group differences, suggesting that IPV severity may be closely linked to both risk of TBI and elevated symptomatology associated with the polytrauma clinical triad. Additionally, as the number of lifetime TBIs increased, the odds of having chronic pain (<i>p</i> = 0.011, <i>OR</i> = 1.17 [1.04, 1.33]) and chronic pain with concurrent neurobehavioral symptoms (<i>p</i> = 0.007, <i>OR</i> = 1.05 [1.05, 1.34]) also increased. These findings suggest that, especially when comorbid with IPV-related TBI, chronic pain may be a priority treatment target among individuals with a history of IPV. Considering that women with a history of IPV often experience concurrent health conditions, multicomponent interventions that address each condition within the polytrauma clinical triad may benefit this population.</p>\",\"PeriodicalId\":16512,\"journal\":{\"name\":\"Journal of neurotrauma\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-06-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of neurotrauma\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1089/neu.2025.0064\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of neurotrauma","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/neu.2025.0064","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
有亲密伴侣暴力史(IPV)的妇女有创伤性脑损伤(TBI)的风险,并伴有持续的神经行为症状、创伤后应激障碍(PTSD)和慢性疼痛,这些共同构成了多重创伤临床三合一的特征。在以男性为主的退伍军人样本中,研究表明,与单独存在三合一的任何组成部分相比,三合一可能会加剧健康问题。目前的研究是首次在经历过IPV的顺性别女性样本中探索多重创伤临床三位一体(N = 198;M = 39.6岁,SD = 11.9;83.3%白人,7.1%西班牙裔;受过大学教育的59.1%)。与无TBI病史的受试者相比,ipvv相关TBI患者的慢性疼痛发生率更高(43.8% vs. 29.0%, p = 0.045,优势比[OR] = 1.87)。1.01, 3.43]), PTSD伴慢性疼痛(19.0%比6.5%,p = 0.009, OR = 3.84[1.41, 10.46]),神经行为症状伴慢性疼痛(40.0%比22.6%,p = 0.030, OR = 2.01[1.07, 3.79]),以及多创伤临床三联征(19.0%比6.5%,p = 0.009, OR = 3.84[1.41, 10.46]),在调整年龄和教育程度后。然而,在控制IPV严重程度后,没有统计学意义上的组差异,这表明IPV严重程度可能与TBI的风险和与多创伤临床三联征相关的症状升高密切相关。此外,随着终身tbi次数的增加,慢性疼痛(p = 0.011, OR = 1.17[1.04, 1.33])和慢性疼痛并发神经行为症状(p = 0.007, OR = 1.05[1.05, 1.34])的几率也增加。这些发现表明,特别是当与IPV相关的TBI合并症时,慢性疼痛可能是有IPV病史的个体的优先治疗目标。考虑到有IPV病史的女性通常会同时出现健康状况,针对多重创伤临床三联征中的每一种情况的多组分干预可能会使这一人群受益。
The Polytrauma Clinical Triad Among Women with a History of Intimate Partner Violence.
Women with a history of intimate partner violence (IPV) are at risk for traumatic brain injury (TBI) with persistent neurobehavioral symptoms, post-traumatic stress disorder (PTSD), and chronic pain, which, together, characterize the polytrauma clinical triad. Among predominantly male Veteran samples, research has suggested that the triad may exacerbate health problems, compared with the presence of any component of the triad alone. The current study is the first to explore the polytrauma clinical triad among a sample of cisgender women who have experienced IPV (N = 198; M = 39.6 years old, SD = 11.9; 83.3% White, 7.1% Hispanic; 59.1% college-educated). Compared with participants without TBI history, participants with IPV-related TBI had higher rates of chronic pain (43.8% vs. 29.0%, p = 0.045, odds ratio [OR] = 1.87 [95% confidence interval: 1.01, 3.43]), PTSD with chronic pain (19.0% vs. 6.5%, p = 0.009, OR = 3.84 [1.41, 10.46]), neurobehavioral symptoms with chronic pain (40.0% vs. 22.6%, p = 0.030, OR = 2.01 [1.07, 3.79]), and the polytrauma clinical triad (19.0% vs. 6.5%, p = 0.009, OR = 3.84 [1.41, 10.46]), after adjusting for age and education. After controlling for IPV severity, however, there were no statistically significant group differences, suggesting that IPV severity may be closely linked to both risk of TBI and elevated symptomatology associated with the polytrauma clinical triad. Additionally, as the number of lifetime TBIs increased, the odds of having chronic pain (p = 0.011, OR = 1.17 [1.04, 1.33]) and chronic pain with concurrent neurobehavioral symptoms (p = 0.007, OR = 1.05 [1.05, 1.34]) also increased. These findings suggest that, especially when comorbid with IPV-related TBI, chronic pain may be a priority treatment target among individuals with a history of IPV. Considering that women with a history of IPV often experience concurrent health conditions, multicomponent interventions that address each condition within the polytrauma clinical triad may benefit this population.
期刊介绍:
Journal of Neurotrauma is the flagship, peer-reviewed publication for reporting on the latest advances in both the clinical and laboratory investigation of traumatic brain and spinal cord injury. The Journal focuses on the basic pathobiology of injury to the central nervous system, while considering preclinical and clinical trials targeted at improving both the early management and long-term care and recovery of traumatically injured patients. This is the essential journal publishing cutting-edge basic and translational research in traumatically injured human and animal studies, with emphasis on neurodegenerative disease research linked to CNS trauma.