抗胸腺细胞球蛋白在免疫介导的细胞减少症中的作用：单中心经验和文献综述。

IF 3.8 2区医学 Q1 HEMATOLOGY

British Journal of Haematology Pub Date : 2025-06-12 DOI:10.1111/bjh.20165

Luca Guarnera, Arooj Ahmed, Carlos Bravo-Perez, Olisaemeka D. Ogbue, Matteo D'Addona, Zachary Brady, Serhan Unlu, Christopher Haddad, Aashray Mandala, Arda Durmaz, Carmelo Gurnari, Valeria Visconte, Jaroslaw P. Maciejewski

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引用次数: 0

摘要

抗胸腺细胞球蛋白治疗多重难治性免疫介导的细胞减少症是一种有效的治疗方法，有效率高达65%。表现为血小板减少症或中性粒细胞减少症的年轻患者，以及LGL和STAT3突变的患者似乎更有可能产生反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Anti-thymocyte globulin in immune-mediated cytopenias: A monocentric experience and literature review

查看原文本刊更多论文

Anti-thymocyte globulin in immune-mediated cytopenias: A monocentric experience and literature review

Anti-thymocyte globulin in multi-refractory immune-mediated cytopenia is an effective treatment, with response rate as high as 65%. Younger patients, presenting with thrombocytopenia or neutropenia, and those with LGL and STAT3 mutations appear to be more likely responsive.

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来源期刊

British Journal of Haematology 医学-血液学

CiteScore

8.60

自引率

4.60%

发文量

565

审稿时长

1 months

期刊介绍： The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.