Emmanuel O Adesuyi, Cynthia A Attah, Oluwatosin A Ige, Confidence C Attamah, Khadijah A Jimoh, Opeoluwa O Olabode, Oluwadamilare Akingbade, Ayobami O Adeagbo, Rafiat Akinokun, Esther Ilesanmi, Mary I Oyeleke, Abiodun E Dairo, Yetunde O Tola
{"title":"污名化，药物依从性和恢复力在新近诊断的艾滋病毒/艾滋病患者（PLWHA）：一项混合方法研究。","authors":"Emmanuel O Adesuyi, Cynthia A Attah, Oluwatosin A Ige, Confidence C Attamah, Khadijah A Jimoh, Opeoluwa O Olabode, Oluwadamilare Akingbade, Ayobami O Adeagbo, Rafiat Akinokun, Esther Ilesanmi, Mary I Oyeleke, Abiodun E Dairo, Yetunde O Tola","doi":"10.1002/puh2.70036","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim and objectives: </strong>To investigate the level of stigma, medication adherence and resilience among recently diagnosed people living with HIV/AIDS (PLWHA) and explore the relationship between medication adherence, stigmatization and resilience.</p><p><strong>Design/method: </strong>This is a convergent-parallel mixed-method design involving both qualitative and quantitative research methodologies. The quantitative aspect utilized a cross-sectional design among 200 PLWHA at the anti-retroviral therapy clinic of the Lagos University Teaching Hospital, Lagos, Nigeria, whereas the qualitative part entailed semi-structured, in-depth interviews of 26 PLWHA. Spearman's rho correlation was used to explore the relationship between medication adherence, stigmatization and resilience, and qualitative data were analysed using thematic analysis.</p><p><strong>Result: </strong>Four themes emerged from the qualitative analysis, including building resilience, experiences relating to diagnosis, experiences related to treatment and factors facilitating medication adherence. Overall, 113 (57%) experienced a high level of stigma, 149 (76%) reported high medication adherence, and above average 115 (57.2%) demonstrated high resilience.</p><p><strong>Conclusion: </strong>In this study, PLWHA in Nigeria who recently received their diagnosis experienced a high level of stigma, resilience and medication adherence. However, nearly one-third of the participants were non-adherent to medication due to several reasons. This noteworthy proportion of non-adherence needs to be addressed while improving resilience and reducing stigmatization.</p>","PeriodicalId":74613,"journal":{"name":"Public health challenges","volume":"4 1","pages":"e70036"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039361/pdf/","citationCount":"0","resultStr":"{\"title\":\"Stigmatization, Medication Adherence and Resilience Among Recently Diagnosed People Living With HIV/AIDS (PLWHA): A Mixed-Method Study.\",\"authors\":\"Emmanuel O Adesuyi, Cynthia A Attah, Oluwatosin A Ige, Confidence C Attamah, Khadijah A Jimoh, Opeoluwa O Olabode, Oluwadamilare Akingbade, Ayobami O Adeagbo, Rafiat Akinokun, Esther Ilesanmi, Mary I Oyeleke, Abiodun E Dairo, Yetunde O Tola\",\"doi\":\"10.1002/puh2.70036\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim and objectives: </strong>To investigate the level of stigma, medication adherence and resilience among recently diagnosed people living with HIV/AIDS (PLWHA) and explore the relationship between medication adherence, stigmatization and resilience.</p><p><strong>Design/method: </strong>This is a convergent-parallel mixed-method design involving both qualitative and quantitative research methodologies. The quantitative aspect utilized a cross-sectional design among 200 PLWHA at the anti-retroviral therapy clinic of the Lagos University Teaching Hospital, Lagos, Nigeria, whereas the qualitative part entailed semi-structured, in-depth interviews of 26 PLWHA. Spearman's rho correlation was used to explore the relationship between medication adherence, stigmatization and resilience, and qualitative data were analysed using thematic analysis.</p><p><strong>Result: </strong>Four themes emerged from the qualitative analysis, including building resilience, experiences relating to diagnosis, experiences related to treatment and factors facilitating medication adherence. Overall, 113 (57%) experienced a high level of stigma, 149 (76%) reported high medication adherence, and above average 115 (57.2%) demonstrated high resilience.</p><p><strong>Conclusion: </strong>In this study, PLWHA in Nigeria who recently received their diagnosis experienced a high level of stigma, resilience and medication adherence. However, nearly one-third of the participants were non-adherent to medication due to several reasons. This noteworthy proportion of non-adherence needs to be addressed while improving resilience and reducing stigmatization.</p>\",\"PeriodicalId\":74613,\"journal\":{\"name\":\"Public health challenges\",\"volume\":\"4 1\",\"pages\":\"e70036\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-02-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039361/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Public health challenges\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/puh2.70036\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Public health challenges","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/puh2.70036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Stigmatization, Medication Adherence and Resilience Among Recently Diagnosed People Living With HIV/AIDS (PLWHA): A Mixed-Method Study.
Aim and objectives: To investigate the level of stigma, medication adherence and resilience among recently diagnosed people living with HIV/AIDS (PLWHA) and explore the relationship between medication adherence, stigmatization and resilience.
Design/method: This is a convergent-parallel mixed-method design involving both qualitative and quantitative research methodologies. The quantitative aspect utilized a cross-sectional design among 200 PLWHA at the anti-retroviral therapy clinic of the Lagos University Teaching Hospital, Lagos, Nigeria, whereas the qualitative part entailed semi-structured, in-depth interviews of 26 PLWHA. Spearman's rho correlation was used to explore the relationship between medication adherence, stigmatization and resilience, and qualitative data were analysed using thematic analysis.
Result: Four themes emerged from the qualitative analysis, including building resilience, experiences relating to diagnosis, experiences related to treatment and factors facilitating medication adherence. Overall, 113 (57%) experienced a high level of stigma, 149 (76%) reported high medication adherence, and above average 115 (57.2%) demonstrated high resilience.
Conclusion: In this study, PLWHA in Nigeria who recently received their diagnosis experienced a high level of stigma, resilience and medication adherence. However, nearly one-third of the participants were non-adherent to medication due to several reasons. This noteworthy proportion of non-adherence needs to be addressed while improving resilience and reducing stigmatization.
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