Karen Zhao, Renée Fournier, Kevin Kennedy, Hilary P Grocott, Emilie Belley-Côté, Matthew Cameron, Richard P Whitlock, C Scott Brudney, Allison M Janda, Eric Jacobsohn, C David Mazer, François Lamontagne, Christie Smith, Gordon Guyatt, Jessica Spence
{"title":"心脏手术期间的血压管理:对加拿大心脏麻醉师、灌注师和心脏外科医生的调查。","authors":"Karen Zhao, Renée Fournier, Kevin Kennedy, Hilary P Grocott, Emilie Belley-Côté, Matthew Cameron, Richard P Whitlock, C Scott Brudney, Allison M Janda, Eric Jacobsohn, C David Mazer, François Lamontagne, Christie Smith, Gordon Guyatt, Jessica Spence","doi":"10.1007/s12630-025-02971-x","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Clinicians presume a relationship between the management of blood pressure during cardiac surgery and postoperative morbidity and mortality. With limited evidence to inform practice, we surveyed Canadian cardiac anesthesiologists, perfusionists, and cardiac surgeons. We sought to solicit information to inform a trial evaluating the blood pressure management approach on outcomes after cardiac surgery.</p><p><strong>Methods: </strong>We iteratively developed a survey assessing the lowest and highest blood pressures respondents would target, the narrowest feasible blood pressure range to achieve, the range of blood pressure observed in clinical practice, and factors influencing targeted blood pressure before, during, and after cardiopulmonary bypass (CPB). We contacted leads from every Canadian hospital providing cardiac surgery to distribute the survey via a computerized link. We used a modified Dillman approach to optimize response rate. Responses were analyzed descriptively.</p><p><strong>Results: </strong>Of 819 clinicians surveyed, 532 (65%) responded. Respondents' lowest pooled mean arterial pressure (MAP) target, presented as mean (standard deviation [SD]), was 59 (6) mm Hg before CPB, 55 (7) mm Hg during CPB, and 60 (5) mm Hg after CPB. Respondents' highest pooled MAP target, presented as mean (SD), was 92 (10) mm Hg before CPB, 84 (7) mm Hg during CPB, and 75 (6) mm Hg after CPB. The narrowest feasible MAP range, presented as mean (SD), all respondents believed could be achieved was 19 (7) mm Hg before CPB, 16 (7) mm Hg during CPB, and 20 (7) mm Hg after CPB.</p><p><strong>Conclusions: </strong>The responses to our survey support the clinical acceptability of a trial examining blood pressure target thresholds at the extreme ends of the range recommended by existing guidelines and the feasibility of maintaining blood pressure within a narrow target range.</p>","PeriodicalId":56145,"journal":{"name":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","volume":" ","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Blood pressure management during cardiac surgery: a survey of Canadian cardiac anesthesiologists, perfusionists, and cardiac surgeons.\",\"authors\":\"Karen Zhao, Renée Fournier, Kevin Kennedy, Hilary P Grocott, Emilie Belley-Côté, Matthew Cameron, Richard P Whitlock, C Scott Brudney, Allison M Janda, Eric Jacobsohn, C David Mazer, François Lamontagne, Christie Smith, Gordon Guyatt, Jessica Spence\",\"doi\":\"10.1007/s12630-025-02971-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Clinicians presume a relationship between the management of blood pressure during cardiac surgery and postoperative morbidity and mortality. With limited evidence to inform practice, we surveyed Canadian cardiac anesthesiologists, perfusionists, and cardiac surgeons. We sought to solicit information to inform a trial evaluating the blood pressure management approach on outcomes after cardiac surgery.</p><p><strong>Methods: </strong>We iteratively developed a survey assessing the lowest and highest blood pressures respondents would target, the narrowest feasible blood pressure range to achieve, the range of blood pressure observed in clinical practice, and factors influencing targeted blood pressure before, during, and after cardiopulmonary bypass (CPB). We contacted leads from every Canadian hospital providing cardiac surgery to distribute the survey via a computerized link. We used a modified Dillman approach to optimize response rate. Responses were analyzed descriptively.</p><p><strong>Results: </strong>Of 819 clinicians surveyed, 532 (65%) responded. Respondents' lowest pooled mean arterial pressure (MAP) target, presented as mean (standard deviation [SD]), was 59 (6) mm Hg before CPB, 55 (7) mm Hg during CPB, and 60 (5) mm Hg after CPB. Respondents' highest pooled MAP target, presented as mean (SD), was 92 (10) mm Hg before CPB, 84 (7) mm Hg during CPB, and 75 (6) mm Hg after CPB. The narrowest feasible MAP range, presented as mean (SD), all respondents believed could be achieved was 19 (7) mm Hg before CPB, 16 (7) mm Hg during CPB, and 20 (7) mm Hg after CPB.</p><p><strong>Conclusions: </strong>The responses to our survey support the clinical acceptability of a trial examining blood pressure target thresholds at the extreme ends of the range recommended by existing guidelines and the feasibility of maintaining blood pressure within a narrow target range.</p>\",\"PeriodicalId\":56145,\"journal\":{\"name\":\"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2025-06-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s12630-025-02971-x\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Canadian Journal of Anesthesia-Journal Canadien D Anesthesie","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12630-025-02971-x","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
Blood pressure management during cardiac surgery: a survey of Canadian cardiac anesthesiologists, perfusionists, and cardiac surgeons.
Purpose: Clinicians presume a relationship between the management of blood pressure during cardiac surgery and postoperative morbidity and mortality. With limited evidence to inform practice, we surveyed Canadian cardiac anesthesiologists, perfusionists, and cardiac surgeons. We sought to solicit information to inform a trial evaluating the blood pressure management approach on outcomes after cardiac surgery.
Methods: We iteratively developed a survey assessing the lowest and highest blood pressures respondents would target, the narrowest feasible blood pressure range to achieve, the range of blood pressure observed in clinical practice, and factors influencing targeted blood pressure before, during, and after cardiopulmonary bypass (CPB). We contacted leads from every Canadian hospital providing cardiac surgery to distribute the survey via a computerized link. We used a modified Dillman approach to optimize response rate. Responses were analyzed descriptively.
Results: Of 819 clinicians surveyed, 532 (65%) responded. Respondents' lowest pooled mean arterial pressure (MAP) target, presented as mean (standard deviation [SD]), was 59 (6) mm Hg before CPB, 55 (7) mm Hg during CPB, and 60 (5) mm Hg after CPB. Respondents' highest pooled MAP target, presented as mean (SD), was 92 (10) mm Hg before CPB, 84 (7) mm Hg during CPB, and 75 (6) mm Hg after CPB. The narrowest feasible MAP range, presented as mean (SD), all respondents believed could be achieved was 19 (7) mm Hg before CPB, 16 (7) mm Hg during CPB, and 20 (7) mm Hg after CPB.
Conclusions: The responses to our survey support the clinical acceptability of a trial examining blood pressure target thresholds at the extreme ends of the range recommended by existing guidelines and the feasibility of maintaining blood pressure within a narrow target range.
期刊介绍:
The Canadian Journal of Anesthesia (the Journal) is owned by the Canadian Anesthesiologists’
Society and is published by Springer Science + Business Media, LLM (New York). From the
first year of publication in 1954, the international exposure of the Journal has broadened
considerably, with articles now received from over 50 countries. The Journal is published
monthly, and has an impact Factor (mean journal citation frequency) of 2.127 (in 2012). Article
types consist of invited editorials, reports of original investigations (clinical and basic sciences
articles), case reports/case series, review articles, systematic reviews, accredited continuing
professional development (CPD) modules, and Letters to the Editor. The editorial content,
according to the mission statement, spans the fields of anesthesia, acute and chronic pain,
perioperative medicine and critical care. In addition, the Journal publishes practice guidelines
and standards articles relevant to clinicians. Articles are published either in English or in French,
according to the language of submission.