活体供肝移植用于肿瘤适应症。

IF 5 2区 医学 Q1 IMMUNOLOGY
Transplantation Pub Date : 2025-10-01 Epub Date: 2025-06-11 DOI:10.1097/TP.0000000000005427
Matthew M Byrne, Mariana Chávez-Villa, Yutaka Endo, Cristina Jimenez-Soto, Luke Cybulski, Luis I Ruffolo, Roberto Hernandez-Alejandro, Koji Tomiyama
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引用次数: 0

摘要

活体供肝移植的肿瘤适应症是一个复杂的话题,涉及移植,肿瘤学和伦理考虑。原发性和继发性肝脏恶性肿瘤的发病率正在增长。随着移植肿瘤学继续提供有希望的结果,可能受益于移植的患者群体将会增长。在这篇综述中,我们通过探讨死亡供体和活体供体肝移植的结果,为肿瘤适应症的移植提供了证据。这将集中于肝细胞癌、胆管癌、神经内分泌肝转移和结直肠肝转移患者的预后。本文旨在总结移植肿瘤学的现状,并提出活体肝移植治疗这些适应症的注意事项。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Live Donor Liver Transplantation for Oncologic Indications.

Living donor liver transplantation for oncologic indications is a complex topic that involves transplantation, oncology, and ethical considerations. The incidence of primary and secondary malignancy of the liver is growing. As transplant oncology continues to provide promising outcomes, the patient population that may benefit from transplantation will grow. In this review, we provide evidence that justify attempting transplantation for oncologic indications through the exploration of outcomes in both deceased donor and living donor liver transplants. This will focus on outcomes for patients with hepatocellular carcinoma, cholangiocarcinoma, neuroendocrine liver metastasis, and colorectal liver metastases. This review aims to summarize the current status of transplant oncology and to develop the considerations of living donor liver transplantation for these indications.

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来源期刊
Transplantation
Transplantation 医学-免疫学
CiteScore
8.50
自引率
11.30%
发文量
1906
审稿时长
1 months
期刊介绍: The official journal of The Transplantation Society, and the International Liver Transplantation Society, Transplantation is published monthly and is the most cited and influential journal in the field, with more than 25,000 citations per year. Transplantation has been the trusted source for extensive and timely coverage of the most important advances in transplantation for over 50 years. The Editors and Editorial Board are an international group of research and clinical leaders that includes many pioneers of the field, representing a diverse range of areas of expertise. This capable editorial team provides thoughtful and thorough peer review, and delivers rapid, careful and insightful editorial evaluation of all manuscripts submitted to the journal. Transplantation is committed to rapid review and publication. The journal remains competitive with a time to first decision of fewer than 21 days. Transplantation was the first in the field to offer CME credit to its peer reviewers for reviews completed. The journal publishes original research articles in original clinical science and original basic science. Short reports bring attention to research at the forefront of the field. Other areas covered include cell therapy and islet transplantation, immunobiology and genomics, and xenotransplantation. ​
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