使用测量和蒙特卡罗模拟的儿科介入心脏病学局部DRL估计和有效剂量计算

IF 2.7 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Pedro Teles , Raquel Costa , Tiago Bettio , Teresa Pinheiro , Teresa Loupa , Joana Santos , Fátima Pinto , Octávia Monteiro Gil , Paolo Ferrari , Maria Zankl
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引用次数: 0

摘要

背景:患有先天性心脏病的儿科患者从x线诊断和介入治疗中获益良多。然而,多种手术导致长时间暴露于电离辐射(IR),引起对继发性长期健康问题的关注。目的:本研究旨在为葡萄牙先天性心脏病国家参考中心(NRCCC)建立当地剂量参考水平(LDRLs)。此外,它使用测量和蒙特卡罗模拟估计了接受冠状动脉造影(CAs)的儿科患者的有效剂量和器官剂量。方法对2022 - 2023年间120例患者的患者登记资料进行统计分析,确定sldrl。对于有效剂量估计,使用拟人化模型(CIRS ATOM 705)和Raysafe剂量计测量个人剂量当量Hp(10),用于验证蒙特卡罗(MC)模拟,然后使用重新缩放的儿科体素模型(GsF婴儿和儿童),以估计不同年龄和体重组具有代表性的患者解剖结构的有效剂量和剂量转换系数(dcc)。结果NRCCC冠状动脉造影sldrls显示出明显的剂量变异性,表明存在剂量优化机会。蒙特卡罗模拟允许器官剂量和有效剂量的计算。新生儿组、1岁组、5岁组和10岁组的剂量转换系数分别为1.107、0.882、0.719和0.524 mSv/Gy·cm2。有效剂量与空气-kerma面积积(KAP)之间存在较强的线性关系。结论该研究强调了有效剂量与KAP之间的强相关性,为临床实践中估计患者剂量和加强辐射安全方案提供了实用框架。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Local DRL estimation and effective dose calculation in paediatric interventional cardiology using measurements and Monte Carlo simulations

Background

Paediatric patients with congenital heart disease benefit greatly from X-ray diagnostic and interventional procedures. However, multiple procedures lead to prolonged exposure to ionizing radiation (IR), raising concerns for secondary long-term health issues.

Purpose

This study aimed to establish local dose reference levels (LDRLs) for a National Reference Center for Congenital Cardiopathies (NRCCC) in Portugal. Additionally, it estimated effective and organ doses in paediatric patients undergoing coronary angiographies (CAs) using measurements and Monte Carlo simulations.

Methods

LDRLs were determined through statistical analysis of patient registry data from 120 patients recorded between 2022 and 2023. For effective dose estimation, personal dose equivalent values Hp(10) were measured with an anthropomorphic phantom (CIRS ATOM 705) and Raysafe dosimeters, used to validate Monte Carlo (MC) simulations, which were then employed with rescaled paediatric voxel phantoms (GsF Baby and Child), to estimate effective doses and dose conversion coefficients (DCCs) for representative patient anatomies across different age and weight groups.

Results

LDRLs for coronary angiographies at the NRCCC showed significant dose variability, indicating dose optimization opportunities. Monte Carlo simulations allowed for organ dose and effective dose calculations. Dose Conversion Coefficients were 1.107, 0.882, 0.719, and 0.524 mSv/Gy·cm2 for newborn, 1 year-old, 5 year-old and 10 year-old groups respectively. A strong linear correlation between effective dose and air-kerma area product (KAP) was observed.

Conclusions

The study highlights the strong correlation between effective dose and KAP, offering a practical framework for estimating patient doses and enhancing radiation safety protocols in clinical practice.
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来源期刊
CiteScore
6.80
自引率
14.70%
发文量
493
审稿时长
78 days
期刊介绍: Physica Medica, European Journal of Medical Physics, publishing with Elsevier from 2007, provides an international forum for research and reviews on the following main topics: Medical Imaging Radiation Therapy Radiation Protection Measuring Systems and Signal Processing Education and training in Medical Physics Professional issues in Medical Physics.
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