恶性肝外胆道梗阻患者经皮放置12mm金属胆道支架：扩展聚四氟乙烯覆盖支架与未覆盖支架的效果

IF 3.2 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology Pub Date : 2025-06-04 DOI:10.1016/j.ejrad.2025.112213

Dong Il Gwon, Hee Ho Chu, Gun Ha Kim, Jihoon Kim, Byung Soo Im, Gi-Young Ko, Hyun-Ki Yoon

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引用次数: 0

摘要

目的探讨经皮置放12mm金属胆道支架治疗恶性肝外胆道梗阻的效果，并比较有盖支架与无盖支架的效果。方法对2020年5月至2022年2月连续49例接受直径12mm膨胀聚四氟乙烯（ePTFE）覆盖支架置入的患者进行回顾性研究。这些患者的数据与2018年12月至2020年4月期间连续48例接受12mm直径无盖支架置入的患者的数据进行了比较。结果两组在技术成功率方面无显著差异(p >；0.999)，内引流成功(p >；0.999)、不良事件发生率（p = 0.774）和患者生存率（p = 0.084）。有盖支架组有8例（16.3%）患者发生不良事件，无盖支架组有6例（12.5%）患者发生不良事件。有盖支架组支架累计通畅率显著高于无盖支架组（p = 0.015）， 6个月时有盖支架组的累计通畅率为97.8%，无盖支架组的累计通畅率为80.8%。覆盖支架组47例患者中有3例（6.4%）发生支架闭塞，未覆盖支架组45例患者中有15例（33.3%）发生支架闭塞，差异有统计学意义（p = 0.001）。结论经皮置放直径12mm金属胆道支架治疗恶性肝外胆道梗阻是安全有效的。此外，ePTFE覆盖支架在支架通畅方面明显优于未覆盖支架。

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Percutaneous placement of 12-mm metallic biliary stents in patients with malignant extrahepatic biliary obstruction: Outcomes of expanded polytetrafluoroethylene-covered stents versus uncovered stents

Purpose

To investigate the outcomes of percutaneous placement of 12-mm metallic biliary stents in patients with malignant extrahepatic biliary obstruction and to compare the outcomes of covered stents with those of uncovered stents.

Methods

From May 2020 to February 2022, 49 consecutive patients who underwent placement of 12-mm-diameter expanded polytetrafluoroethylene (ePTFE) covered stents were retrospectively studied. The data from these patients were compared with data from 48 consecutive patients who underwent 12-mm-diameter uncovered stent placement between December 2018 and April 2020.

Results

There were no significant differences in technical success (p > 0.999), successful internal drainage (p > 0.999), adverse events (p = 0.774), and patient survival (p = 0.084) between the two groups. Adverse events occurred in eight (16.3 %) patients in the covered stent group and six (12.5 %) in the uncovered stent group. Cumulative stent patency rate was significantly higher in the covered stent group than in the uncovered stent group (p = 0.015), with cumulative patency rate at 6 months being 97.8 % in the covered stent group and 80.8 % in the uncovered stent group. Stent occlusion occurred in 3 (6.4 %) of 47 patients in the covered stent group and 15 (33.3 %) of 45 patients (41 %) in the uncovered stent group, with this difference being significant (p = 0.001).

Conclusion

Percutaneous placement of 12-mm-diameter metallic biliary stents is effective and safe in patients with malignant extrahepatic biliary obstruction. Moreover, ePTFE covered stents were significantly superior to uncovered stents in terms of stent patency.

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来源期刊

European Journal of Radiology 医学-核医学

CiteScore

6.70

自引率

3.00%

发文量

398

审稿时长

42 days

期刊介绍： European Journal of Radiology is an international journal which aims to communicate to its readers, state-of-the-art information on imaging developments in the form of high quality original research articles and timely reviews on current developments in the field. Its audience includes clinicians at all levels of training including radiology trainees, newly qualified imaging specialists and the experienced radiologist. Its aim is to inform efficient, appropriate and evidence-based imaging practice to the benefit of patients worldwide.