首发进食障碍患者未治疗症状持续时间与临床结果的关系

Psychiatry research communications Pub Date : 2025-06-01 DOI:10.1016/j.psycom.2025.100217

Amelia Austin , Michaela Flynn , Katie Richards , Karina Allen , Victoria A. Mountford , Danielle Glennon , Amy Brown , Nina Grant , Mary Franklin-Smith , Monique Schelhase , William Rhys Jones , Gabrielle Brady , Lucy Serpell , Ulrike Schmidt

{"title":"首发进食障碍患者未治疗症状持续时间与临床结果的关系","authors":"Amelia Austin , Michaela Flynn , Katie Richards , Karina Allen , Victoria A. Mountford , Danielle Glennon , Amy Brown , Nina Grant , Mary Franklin-Smith , Monique Schelhase , William Rhys Jones , Gabrielle Brady , Lucy Serpell , Ulrike Schmidt","doi":"10.1016/j.psycom.2025.100217","DOIUrl":null,"url":null,"abstract":"<div><div>The relationship between duration of untreated symptoms and clinical outcomes in eating disorders (EDs) is not fully understood. We explored whether the duration of prodrome (DOP) or duration of untreated eating disorder (DUED) impacts clinical outcomes. Emerging adults (N = 236) aged 16–25 years, with an early-stage ED were recruited at the outset of treatment, completing a semi-structured interview to establish DOP and DUED. Clinical outcomes were measured at baseline and 12-months. DUED was positively correlated with binge eating (rs = .236, p < .001) and vomiting (rs = .131, p = .047) at baseline, and negatively correlated with BMI for anorexia nervosa at follow-up (rs [58] = -.26, p = .038). After subsequent regression analysis, the only significant finding was DUED as a predictor of the presence of binge eating at baseline. Future studies should examine symptom duration in more diverse samples.</div></div>","PeriodicalId":74595,"journal":{"name":"Psychiatry research communications","volume":"5 2","pages":"Article 100217"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The relationship between duration of untreated symptoms and clinical outcomes in first episode eating disorders\",\"authors\":\"Amelia Austin , Michaela Flynn , Katie Richards , Karina Allen , Victoria A. Mountford , Danielle Glennon , Amy Brown , Nina Grant , Mary Franklin-Smith , Monique Schelhase , William Rhys Jones , Gabrielle Brady , Lucy Serpell , Ulrike Schmidt\",\"doi\":\"10.1016/j.psycom.2025.100217\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The relationship between duration of untreated symptoms and clinical outcomes in eating disorders (EDs) is not fully understood. We explored whether the duration of prodrome (DOP) or duration of untreated eating disorder (DUED) impacts clinical outcomes. Emerging adults (N = 236) aged 16–25 years, with an early-stage ED were recruited at the outset of treatment, completing a semi-structured interview to establish DOP and DUED. Clinical outcomes were measured at baseline and 12-months. DUED was positively correlated with binge eating (rs = .236, p < .001) and vomiting (rs = .131, p = .047) at baseline, and negatively correlated with BMI for anorexia nervosa at follow-up (rs [58] = -.26, p = .038). After subsequent regression analysis, the only significant finding was DUED as a predictor of the presence of binge eating at baseline. Future studies should examine symptom duration in more diverse samples.</div></div>\",\"PeriodicalId\":74595,\"journal\":{\"name\":\"Psychiatry research communications\",\"volume\":\"5 2\",\"pages\":\"Article 100217\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Psychiatry research communications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772598725000169\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychiatry research communications","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772598725000169","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

进食障碍（EDs）症状未治疗的持续时间与临床结果之间的关系尚不完全清楚。我们探讨了前驱期（DOP）或未治疗进食障碍（DUED）的持续时间是否会影响临床结果。在治疗开始时招募年龄16-25岁、早期ED的新生成人（N = 236），完成半结构化访谈以确定DOP和DUED。在基线和12个月时测量临床结果。DUED与暴食呈正相关(rs = 0.236, p <；.001)和呕吐（rs = 0.131, p = 0.047），随访时神经性厌食症与BMI呈负相关（rs[58] = -）。26, p = .038)。在随后的回归分析后，唯一有意义的发现是DUED作为基线暴食存在的预测因子。未来的研究应该在更多不同的样本中检查症状持续时间。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The relationship between duration of untreated symptoms and clinical outcomes in first episode eating disorders

The relationship between duration of untreated symptoms and clinical outcomes in eating disorders (EDs) is not fully understood. We explored whether the duration of prodrome (DOP) or duration of untreated eating disorder (DUED) impacts clinical outcomes. Emerging adults (N = 236) aged 16–25 years, with an early-stage ED were recruited at the outset of treatment, completing a semi-structured interview to establish DOP and DUED. Clinical outcomes were measured at baseline and 12-months. DUED was positively correlated with binge eating (r_s = .236, p < .001) and vomiting (r_s = .131, p = .047) at baseline, and negatively correlated with BMI for anorexia nervosa at follow-up (r_s [58] = -.26, p = .038). After subsequent regression analysis, the only significant finding was DUED as a predictor of the presence of binge eating at baseline. Future studies should examine symptom duration in more diverse samples.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Psychiatry research communications Psychiatry and Mental Health

CiteScore

1.40

自引率

0.00%

发文量

审稿时长

77 days