用于识别癌症类型的混合深度学习模型

Singamaneni Krishnapriya , Hyma Birudaraju , M. Madhulatha , S. Nagajyothi , K.S. Ranadheer Kumar
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引用次数: 0

摘要

尽管目前取得了进展,但癌症仍然是全球最大的健康挑战之一,必须及早诊断才能开始治疗。在这项工作中,我们引入了一个基于混合深度学习的框架,通过使用预训练的卷积神经网络、自定义深度学习网络和传统机器学习分类器来准确识别癌症类型和亚型。我使用CNN + LSTM的先进架构和基于注意力的模型,以及VGG19、Xception和AmoebaNet的预训练模型,在更复杂的癌症数据集上取得了准确的结果。利用基于置信度和异或融合等集成技术进一步提高了模型的可靠性和可解释性。在多个多模态数据集上的实验结果表明,我们的混合方法通过提高准确率、召回率和F1分数在各种类型癌症中的有效性。然而,它们已经有了很好的结果,并且仍然具有挑战性,无法用于罕见的癌症亚型或解释以获得临床应用。提出的框架通过开发机器学习创新来推进精准医疗,为个性化癌症提供了基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hybrid deep learning model for identifying the cancer type
Despite current advances, cancer remains one of the biggest health challenges globally, and diagnosis must be made earlier to begin treatment. In this work, we introduce a hybrid deep learning-based framework for accurate cancer type and subtype identification by using pre-trained convolutional neural networks, custom deep learning networks, and traditional machine learning classifiers. I have achieved accurate results on more complex cancer datasets using advanced architectures of CNN + LSTM and attention-based models, along with the pre-trained models of VGG19, Xception, and AmoebaNet. Model reliability and interpretability are further improved using ensemble techniques such as confidence-based and XOR fusion. Experimental results in multiple multimodal datasets demonstrate the effectiveness of our hybrid approach by improving precision, recall, and F1 scores in various types of cancer. However, they have promising results and remain challenging to deploy for rare cancer subtypes or explain to gain clinical adoption. The proposed framework provides a basis for personalized cancer by developing machine learning innovations to advance precision medicine.
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