Angela Milo, Lijinghan Chen, Kyle A. Grice* and David A. Vosburg*,
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Alternatives to Dichloromethane for Teaching Laboratories
New US regulations restricting dichloromethane (DCM), also called methylene chloride, may prompt instructors of teaching laboratories to avoid its use entirely. This commentary addresses the hazards, properties, and laboratory applications of DCM, as well as strategies and resources for adopting or designing DCM-free experiments. Examples include solvent-free protocols and using greener, less hazardous solvents. Procedures for reactions, extractions, and chromatography are described, with a particular emphasis on ethyl acetate as a first alternative solvent for many applications. Readers are encouraged to reference the CHEM21 solvent guide and join the Green Chemistry Teaching and Learning Community (GCTLC) to share their experiences, best practices, and alternative approaches to further promote a safer environment for students and staff in teaching laboratories across the country and around the world.
期刊介绍：
The Journal of Chemical Education is the official journal of the Division of Chemical Education of the American Chemical Society, co-published with the American Chemical Society Publications Division. Launched in 1924, the Journal of Chemical Education is the world’s premier chemical education journal. The Journal publishes peer-reviewed articles and related information as a resource to those in the field of chemical education and to those institutions that serve them. JCE typically addresses chemical content, activities, laboratory experiments, instructional methods, and pedagogies. The Journal serves as a means of communication among people across the world who are interested in the teaching and learning of chemistry. This includes instructors of chemistry from middle school through graduate school, professional staff who support these teaching activities, as well as some scientists in commerce, industry, and government.
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