杂志俱乐部：多发性硬化症患者的癌症风险：一项10年全国回顾性队列研究。

IF 8.5 1区医学 Q1 CLINICAL NEUROLOGY

Neurology Pub Date : 2025-07-01 Epub Date: 2025-06-05 DOI:10.1212/WNL.0000000000213663

Analisa Jia, Tiffany Rose Price, Jan Rosner, Conor Broderick, Jacquelyn Judith Cragg

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引用次数: 0

摘要

这篇杂志俱乐部的文章讨论了Pierret等人研究多发性硬化症（MS）患者癌症风险的优势和局限性。在这项研究之前，MS与癌症风险之间的关系尚不清楚，因为一些研究表明风险增加，而另一些研究表明风险降低，这凸显了在理解这种复杂联系方面的重大知识差距。了解多发性硬化症如何影响癌症易感性对评估治疗安全性和改善患者护理至关重要。这项研究表明，多发性硬化症患者患癌症的风险，尤其是泌尿生殖系统癌症的风险略有升高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal Club: Cancer Risk Among Patients With Multiple Sclerosis: A 10-Year Nationwide Retrospective Cohort Study.

This journal club article discusses the strengths and limitations of a study from Pierret et al., which examined cancer risk for patients with multiple sclerosis (MS). Before this study, the relationship between MS and cancer risk was unclear because some studies suggested an increased risk while others indicated a decreased risk, highlighting a significant knowledge gap in understanding this complex connection. It is essential to understand how MS may influence cancer susceptibility to assess treatment safety and improve patient care. This study demonstrated that cancer risk, especially for urogenital cancers, was modestly elevated in people with MS.

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来源期刊

Neurology 医学-临床神经学

CiteScore

12.20

自引率

4.00%

发文量

1973

审稿时长

2-3 weeks

期刊介绍： Neurology, the official journal of the American Academy of Neurology, aspires to be the premier peer-reviewed journal for clinical neurology research. Its mission is to publish exceptional peer-reviewed original research articles, editorials, and reviews to improve patient care, education, clinical research, and professionalism in neurology. As the leading clinical neurology journal worldwide, Neurology targets physicians specializing in nervous system diseases and conditions. It aims to advance the field by presenting new basic and clinical research that influences neurological practice. The journal is a leading source of cutting-edge, peer-reviewed information for the neurology community worldwide. Editorial content includes Research, Clinical/Scientific Notes, Views, Historical Neurology, NeuroImages, Humanities, Letters, and position papers from the American Academy of Neurology. The online version is considered the definitive version, encompassing all available content. Neurology is indexed in prestigious databases such as MEDLINE/PubMed, Embase, Scopus, Biological Abstracts®, PsycINFO®, Current Contents®, Web of Science®, CrossRef, and Google Scholar.