Denise Brown, Edit Gedeon, Marion Henderson, Alastair H Leyland, Philip Wilson, Mirjam Allik
{"title":"接受过护理的儿童和年轻人的死亡率结果:来自苏格兰儿童保健的证据,这是一项全人口的行政数据队列研究。","authors":"Denise Brown, Edit Gedeon, Marion Henderson, Alastair H Leyland, Philip Wilson, Mirjam Allik","doi":"10.1136/archdischild-2024-327854","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Individuals who spend time in care during childhood/adolescence face a higher risk of premature mortality compared with those who have not been in care. However, it is unclear whether this risk applies to both external causes of death (eg, accident or suicide) and internal causes (eg, disease), as well as the role of potential confounders.</p><p><strong>Design: </strong>A descriptive, population-wide cohort study linking administrative data on state school pupils in Scotland with social care records and vital event data for children and young people with (n=12 367) and without (n=6 49 711) experience of care.</p><p><strong>Outcome: </strong>Premature mortality between 2010 and 2016.</p><p><strong>Analysis: </strong>Poisson regression, with robust SEs, was used to calculate mortality rate ratios, adjusting for confounders age group, sex, area deprivation, disability, and sociodemographic characteristics at birth.</p><p><strong>Results: </strong>Of 745 deaths, 58 were among those with care experience. Of these, 66% were due to external causes, compared with 43% in those without care experience. The unadjusted mortality rate was 4.5 (95% CI 2.6 to 7.7) times as high for those with care experience. After adjusting for confounders, the rate ratio (RR) was 3.0 (95% CI 2.0 to 4.4). Adjusting for confounders did not account for differences in external causes; RR 6.5 (95% CI 4.5 to 9.5), but did account for differences in internal causes; RR 1.4 (95% CI 0.9 to 2.3).</p><p><strong>Conclusions: </strong>Individuals with care experience have higher premature mortality rates, particularly from external causes, compared with those without care experience, a difference not fully accounted for by the confounders considered here. Further research is needed to explore factors contributing to excess external deaths in this population.</p>","PeriodicalId":8150,"journal":{"name":"Archives of Disease in Childhood","volume":" ","pages":"837-843"},"PeriodicalIF":3.2000,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mortality outcomes of children and young people who have spent time in care: evidence from Children's Health in Care in Scotland, a population-wide administrative data cohort study.\",\"authors\":\"Denise Brown, Edit Gedeon, Marion Henderson, Alastair H Leyland, Philip Wilson, Mirjam Allik\",\"doi\":\"10.1136/archdischild-2024-327854\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Individuals who spend time in care during childhood/adolescence face a higher risk of premature mortality compared with those who have not been in care. However, it is unclear whether this risk applies to both external causes of death (eg, accident or suicide) and internal causes (eg, disease), as well as the role of potential confounders.</p><p><strong>Design: </strong>A descriptive, population-wide cohort study linking administrative data on state school pupils in Scotland with social care records and vital event data for children and young people with (n=12 367) and without (n=6 49 711) experience of care.</p><p><strong>Outcome: </strong>Premature mortality between 2010 and 2016.</p><p><strong>Analysis: </strong>Poisson regression, with robust SEs, was used to calculate mortality rate ratios, adjusting for confounders age group, sex, area deprivation, disability, and sociodemographic characteristics at birth.</p><p><strong>Results: </strong>Of 745 deaths, 58 were among those with care experience. Of these, 66% were due to external causes, compared with 43% in those without care experience. The unadjusted mortality rate was 4.5 (95% CI 2.6 to 7.7) times as high for those with care experience. After adjusting for confounders, the rate ratio (RR) was 3.0 (95% CI 2.0 to 4.4). Adjusting for confounders did not account for differences in external causes; RR 6.5 (95% CI 4.5 to 9.5), but did account for differences in internal causes; RR 1.4 (95% CI 0.9 to 2.3).</p><p><strong>Conclusions: </strong>Individuals with care experience have higher premature mortality rates, particularly from external causes, compared with those without care experience, a difference not fully accounted for by the confounders considered here. Further research is needed to explore factors contributing to excess external deaths in this population.</p>\",\"PeriodicalId\":8150,\"journal\":{\"name\":\"Archives of Disease in Childhood\",\"volume\":\" \",\"pages\":\"837-843\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-09-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Disease in Childhood\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1136/archdischild-2024-327854\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Disease in Childhood","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1136/archdischild-2024-327854","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
摘要
目的:在儿童/青少年时期接受护理的个体与未接受护理的个体相比,面临更高的过早死亡风险。然而,尚不清楚这种风险是否既适用于死亡的外部原因(例如事故或自杀),也适用于内部原因(例如疾病),以及潜在混杂因素的作用。设计:一项描述性、全人群队列研究,将苏格兰公立学校学生的行政数据与有(n=12 367)和没有(n=6 49 711)护理经验的儿童和年轻人的社会护理记录和重大事件数据联系起来。结果:2010年至2016年期间的过早死亡率。分析:泊松回归,稳健的se,用于计算死亡率比,调整混杂因素,年龄、性别、地区剥夺、残疾和出生时的社会人口特征。结果:745例死亡中,58例有护理经历。其中,66%是由于外部原因,而在没有护理经历的人中,这一比例为43%。未经调整的死亡率是有护理经验者的4.5倍(95% CI 2.6 - 7.7)。调整混杂因素后,发病率比(RR)为3.0 (95% CI 2.0至4.4)。对混杂因素的调整没有考虑外部原因的差异;RR为6.5 (95% CI为4.5 - 9.5),但确实解释了内因的差异;RR 1.4 (95% CI 0.9 ~ 2.3)。结论:与没有护理经历的个体相比,有护理经历的个体有更高的过早死亡率,特别是由外部原因引起的死亡率,这里考虑的混杂因素不能完全解释这一差异。需要进一步的研究来探索导致这一人群外部死亡过多的因素。
Mortality outcomes of children and young people who have spent time in care: evidence from Children's Health in Care in Scotland, a population-wide administrative data cohort study.
Objective: Individuals who spend time in care during childhood/adolescence face a higher risk of premature mortality compared with those who have not been in care. However, it is unclear whether this risk applies to both external causes of death (eg, accident or suicide) and internal causes (eg, disease), as well as the role of potential confounders.
Design: A descriptive, population-wide cohort study linking administrative data on state school pupils in Scotland with social care records and vital event data for children and young people with (n=12 367) and without (n=6 49 711) experience of care.
Outcome: Premature mortality between 2010 and 2016.
Analysis: Poisson regression, with robust SEs, was used to calculate mortality rate ratios, adjusting for confounders age group, sex, area deprivation, disability, and sociodemographic characteristics at birth.
Results: Of 745 deaths, 58 were among those with care experience. Of these, 66% were due to external causes, compared with 43% in those without care experience. The unadjusted mortality rate was 4.5 (95% CI 2.6 to 7.7) times as high for those with care experience. After adjusting for confounders, the rate ratio (RR) was 3.0 (95% CI 2.0 to 4.4). Adjusting for confounders did not account for differences in external causes; RR 6.5 (95% CI 4.5 to 9.5), but did account for differences in internal causes; RR 1.4 (95% CI 0.9 to 2.3).
Conclusions: Individuals with care experience have higher premature mortality rates, particularly from external causes, compared with those without care experience, a difference not fully accounted for by the confounders considered here. Further research is needed to explore factors contributing to excess external deaths in this population.
期刊介绍:
Archives of Disease in Childhood is an international peer review journal that aims to keep paediatricians and others up to date with advances in the diagnosis and treatment of childhood diseases as well as advocacy issues such as child protection. It focuses on all aspects of child health and disease from the perinatal period (in the Fetal and Neonatal edition) through to adolescence. ADC includes original research reports, commentaries, reviews of clinical and policy issues, and evidence reports. Areas covered include: community child health, public health, epidemiology, acute paediatrics, advocacy, and ethics.