音乐干预对危重病人焦虑的影响：随机对照试验的荟萃分析

IF 3.2 3区医学 Q2 CRITICAL CARE MEDICINE

Journal of critical care Pub Date : 2025-06-07 DOI:10.1016/j.jcrc.2025.155133

Muhammad Saqib , Asia Batool , Qurat Ul Ain Iftikhar , Makhzan Ali Akbar , Faiza Hayat Qadri , Kanz Ul Eman Maryam , Syeda Alishba Zahra Naqvi , Asiya Najam Ul Haq , Fareeha Hasan

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引用次数: 0

摘要

音乐疗法已被探索作为一种非药物干预的焦虑危重病人，但其有效性尚不清楚。本荟萃分析综合了涉及325名受试者的5项随机对照试验（rct）的证据。对PubMed、Embase和Cochrane数据库进行了全面的文献检索，确保纳入了2010年至2025年间发表的高质量研究。音乐治疗时间从15分钟到30分钟不等。使用有效的测量方法评估焦虑，并使用随机效应模型分析数据，以95%的置信区间（CI）计算焦虑评分的平均差异（MD）。使用I2统计量评估异质性，并进行敏感性分析以解决潜在偏倚。合并分析发现MD为- 1.11 (95% CI: - 12.97 ~ 10.75, p = 0.85；I2 = 99%)，没有明显的焦虑减轻。异质性很大。敏感度分析，排除两项有影响的研究，减少了异质性（I2 = 30%），但仍未显示显著影响（MD = 0.69, 95% CI: - 2.15至3.53,p = 0.63）。漏斗图提示可能存在发表偏倚，但研究数量有限阻碍了正式评估。总的来说，目前的证据并不支持音乐疗法作为减轻危重病人焦虑的有效独立干预。有必要进一步研究标准化方案和更大的样本量，以明确其在重症监护环境中的作用。

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Effect of music intervention on anxiety in critically ill patients, a meta-analysis of randomized controlled trials

Music therapy has been explored as a non-pharmacological intervention for anxiety in critically ill patients, but its effectiveness remains unclear. This meta-analysis synthesized evidence from five randomized controlled trials (RCTs) involving 325 participants. A comprehensive literature search across PubMed, Embase, and Cochrane databases ensured the inclusion of high-quality studies published between 2010 and 2025. Music therapy sessions ranged from 15 to 30 min. Anxiety was assessed using validated measures, and data were analyzed with a random-effects model to calculate the mean difference (MD) in anxiety scores with 95 % confidence intervals (CI). Heterogeneity was evaluated using the I2 statistic, and sensitivity analyses were conducted to address potential bias.

The pooled analysis found an MD of −1.11 (95 % CI: −12.97 to 10.75, p = 0.85; I2 = 99 %), showing no significant anxiety reduction. Heterogeneity was substantial. A sensitivity analysis, excluding two influential studies, reduced heterogeneity (I2 = 30 %) but still showed no significant effect (MD = 0.69, 95 % CI: −2.15 to 3.53, p = 0.63). A funnel plot suggested possible publication bias, but the limited number of studies hindered formal assessment.

Overall, current evidence does not support music therapy as an effective stand-alone intervention for anxiety reduction in critically ill patients. Further research with standardized protocols and larger sample sizes is necessary to clarify its role in critical care settings.

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来源期刊

Journal of critical care 医学-危重病医学

CiteScore

8.60

自引率

2.70%

发文量

237

审稿时长

23 days

期刊介绍： The Journal of Critical Care, the official publication of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM), is a leading international, peer-reviewed journal providing original research, review articles, tutorials, and invited articles for physicians and allied health professionals involved in treating the critically ill. The Journal aims to improve patient care by furthering understanding of health systems research and its integration into clinical practice. The Journal will include articles which discuss: All aspects of health services research in critical care System based practice in anesthesiology, perioperative and critical care medicine The interface between anesthesiology, critical care medicine and pain Integrating intraoperative management in preparation for postoperative critical care management and recovery Optimizing patient management, i.e., exploring the interface between evidence-based principles or clinical insight into management and care of complex patients The team approach in the OR and ICU System-based research Medical ethics Technology in medicine Seminars discussing current, state of the art, and sometimes controversial topics in anesthesiology, critical care medicine, and professional education Residency Education.