分流支架在颅内动脉夹层破裂治疗中的应用。

Surgical neurology international Pub Date : 2025-05-09 eCollection Date: 2025-01-01 DOI:10.25259/SNI_1062_2024
Muhammad Omar Afridi, Stephen Joseph Sozio, Sudipta Roychowdhury, Gaurav Gupta, Emad Nourollah-Zadeh, Hai Sun, Arevik Abramyan, Sri Hari Sundararajan
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引用次数: 0

摘要

背景:血流分流支架作为颅内动脉瘤的首选治疗方法已迅速普及。它们的作用是优化母血管内的血流,以减少动脉瘤内的剪切应力,促进动脉瘤内血栓的形成,并为内皮化和血管重塑提供支架。早期文献表明,该机制也适用于颅内动脉瘤破裂和未破裂颅内动脉夹层的治疗,显示出良好的闭塞率。我们强调了一种新的应用血流分流支架在治疗破裂的颅内动脉夹层。病例描述:回顾性回顾了两例大脑中动脉夹层破裂的成年患者,其中在夹层上放置了血流再定向腔内装置X (FRED X支架,Microvention™,美国)。利用FRED X支架的血流转移和血管重塑特性,两例患者均实现了止血,维持腔内通畅,最终解决出血,无任何治疗相关并发症。短期随访未见出血复发。结论:血流分流支架有望成为治疗颅内动脉夹层破裂的可行选择。然而,建议进一步的前瞻性研究来全面评估其疗效和长期预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Use of flow-diverting stents in the treatment of ruptured intracranial artery dissections.

Background: Flow-diverting stents have rapidly become widespread as the preferred treatment for intracranial aneurysms. They function by optimizing blood flow within the parent vessel to reduce shear stress in the aneurysm, facilitating thrombus formation within the aneurysm, and providing a scaffold for endothelialization and vascular remodeling. Early literature indicates this mechanism also applies to the treatment of ruptured intracranial aneurysms and unruptured intracranial artery dissections, demonstrating favorable occlusion rates. We highlight a novel application of flow-diverting stents in the treatment of ruptured intracranial artery dissections.

Case description: A retrospective chart review was performed of two adult patients suffering from ruptured middle cerebral artery dissections, in which a Flow Re-direction Endoluminal Device X (FRED X stent, Microvention, USA) was deployed across the dissection. Utilizing both the flow diverting and vascular remodeling properties of the FRED X stent, both patients achieved hemostasis, maintenance intraluminal patency, and ultimately resolution of hemorrhage without any treatment-related complications. Short-term follow-up revealed no bleeding recurrence.

Conclusion: Flow-diverting stents show promise as a viable option for managing ruptured intracranial artery dissections. However, further prospective studies are recommended to evaluate their efficacy and long-term outcomes comprehensively.

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