盆腔血管栓塞会增加盆腔缺血并发症吗?美国创伤外科研究多中心协会。

IF 3.8 2区 医学 Q1 SURGERY
Michael Artigue, Thomas Schroeppel, Brian Sheehan, Jeffry Nahmias, James Bradford, Laura Haines, Elizabeth Benjamin, Deepika Koganti, Stephany Kim, Jennifer Mooney
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引用次数: 0

摘要

背景:盆腔血管栓塞术(PAE)是否会引起盆腔缺血性并发症以及选择性与非选择性栓塞是否会影响这些并发症的风险存在争议。方法:我们进行了一项多中心前瞻性观察研究,对骨盆骨折的成人钝性创伤患者进行了超过55个月的血管造影。接受血管造影的患者分为四组:无栓塞(no - embo)、选择性栓塞(Sel)、单侧非选择性栓塞(Non-Sel)和双侧非Sel栓塞(B-Non-Sel)。主要结局为缺血性并发症;定义为臀皮肤/肌肉坏死、盆腔脓肿、盆腔伤口感染、盆腔伤口破裂、骨盆或股骨头骨髓炎。结果:460例血管造影患者中,盆腔缺血性并发症45例(9.8%)。45例患者中,No-Embo组4例(5.1%),Sel组24例(10.0%),Non-Sel组11例(15.1%),B-Non-Sel组6例(8.8%)。单因素分析(p=0.23)、多因素分析(Sel OR=2.16, p=0.3;非sel OR=4.17, p=0.07;B-Non-Sel OR=1.00, p=0.99)。结论:目前的研究是迄今为止对钝性骨盆骨折患者进行血管造影的最大研究。通过比较未栓塞、选择性栓塞和非选择性栓塞的患者,我们发现PAE和盆腔缺血并发症之间没有关联。何时何地栓塞的决定应根据所遇到的损伤和患者的稳定情况进行个体化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Does Pelvic Angioembolization Increase Pelvic Ischemic Complication? A Multicenter American Association for the Surgery of Trauma Study.

Background: Controversy exists if pelvic angioembolization (PAE) causes ischemic complications of the pelvis and if selective vs non-selective embolization influences the risk of these complications.

Methods: We conducted a multicenter prospective observational study of adult blunt trauma patients with pelvic fractures who underwent angiography over 55 months. Patients who underwent angiography were divided into four groups: no embolization (No-Embo), selective embolization (Sel), unilateral nonselective embolization (Non-Sel) and bilateral Non-Sel embolization (B-Non-Sel). The primary outcome was ischemic complications; defined as gluteal skin/muscle necrosis, pelvic abscess, pelvic wound infection, pelvic wound breakdown, and osteomyelitis of the pelvis or femoral head.

Results: Of the 460 patients undergoing angiography, pelvic ischemic complications occurred in 45 patients (9.8%). Of these 45 patients, 4 patients were in the No-Embo group (5.1%), 24 patients (10.0%) in the Sel group, 11 patients (15.1%) in the Non-Sel group, and 6 patients (8.8%) in the B-Non-Sel. There was no significant difference when comparing the groups on univariate analysis (p=0.23), multivariable analysis (Sel OR=2.16, p=0.3; Non-Sel OR=4.17, p=0.07; B-Non-Sel OR=1.00, p=0.99) nor when comparing each complication individually.

Conclusion: The current study is the largest to date of blunt pelvic fracture patients undergoing angiography. Upon comparing those not embolized with those selectively and non-selectively embolized, we found no association between PAE and pelvic ischemic complications. The decision of when and where to embolize should be individualized to the injury encountered and the stability of the patient.

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来源期刊
CiteScore
6.90
自引率
5.80%
发文量
1515
审稿时长
3-6 weeks
期刊介绍: The Journal of the American College of Surgeons (JACS) is a monthly journal publishing peer-reviewed original contributions on all aspects of surgery. These contributions include, but are not limited to, original clinical studies, review articles, and experimental investigations with clear clinical relevance. In general, case reports are not considered for publication. As the official scientific journal of the American College of Surgeons, JACS has the goal of providing its readership the highest quality rapid retrieval of information relevant to surgeons.
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