硼催化下亚甲基环丙烷的区域选择性环保留氢硅化反应

IF 5 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2025-05-27 DOI:10.1021/acs.orglett.5c0172010.1021/acs.orglett.5c01720

Rui Lin, Min Ou, Qian Ni, Xianmao Liu, Zhen Song, Xinmiao Huang, Wei Yao, Yaqi Chen, Jinxing Long, Weiqi Song and Yuanhong Ma*,

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引用次数: 0

摘要

本文报道了在B(C6F5)3催化剂催化下，甲基环丙烷（MCPs）与氢硅烷的高度区域选择性环保留氢硅化反应。该催化方案为硅基环丙烷的合成提供了一种原子高效的途径，具有100%的原子效率、广泛的底物范围（42个例子）、温和的条件和高的区域选择性和化学选择性。目前的无金属催化硅氢化也为从mcp合成结构多样的有机硅化合物提供了一种互补途径，而不是过渡金属催化的变体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Boron Catalysis-Enabled Regioselective Ring-Retentive Hydrosilylation of Methylenecyclopropanes

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Boron Catalysis-Enabled Regioselective Ring-Retentive Hydrosilylation of Methylenecyclopropanes

Herein, we report the highly regioselective ring-retentive hydrosilylation of methylenecyclopropanes (MCPs) with hydrosilanes by a B(C₆F₅)₃ catalyst. The catalytic protocol affords an atom-efficient route for the synthesis of silylcyclopropanes, featuring 100% atom-efficiency, broad substrate scope (42 examples), mild conditions, and high regio-, and chemoselectivity. The current metal-free catalytic hydrosilylation also provides a complementary pathway for the synthesis of structurally diverse organosilicon compounds from MCPs over transition metal-catalyzed variants.

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.