Identifying and mitigating algorithmic bias in the safety net

Algorithmic bias occurs when predictive model performance varies meaningfully across sociodemographic classes, exacerbating systemic healthcare disparities. NYC Health + Hospitals, an urban safety net system, assessed bias in two binary classification models in our electronic medical record: one predicting acute visits for asthma and one predicting unplanned readmissions. We evaluated differences in subgroup performance across race/ethnicity, sex, language, and insurance using equal opportunity difference (EOD), a metric comparing false negative rates. The most biased classes (race/ethnicity for asthma, insurance for readmission) were targeted for mitigation using threshold adjustment, which adjusts subgroup thresholds to minimize EOD, and reject option classification, which re-classifies scores near the threshold by subgroup. Successful mitigation was defined as 1) absolute subgroup EODs <5 percentage points, 2) accuracy reduction <10%, and 3) alert rate change <20%. Threshold adjustment met these criteria; reject option classification did not. We introduce a Supplementary Playbook outlining our approach for low-resource bias mitigation.