{"title":"宫颈癌患者接受调强放疗与三维放疗剂量学参数的比较评价：回顾性分析。","authors":"Vishwadeep Mishra, Sudeep Bisht, Shwetima Chaudhary, Laxman Pandey, Archana Pandey, Rachita Chatterjee","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Cervical cancer affects many women across the globe and often requires radiation for treatment. This study aimed to compare the dosimetric outcomes of Intensity-Modulated Radiation Therapy (IMRT) and Three- Dimensional Conformal Radiation Therapy (3D-CRT) in managing locally advanced cervical carcinoma.</p><p><strong>Methods: </strong>We performed a retrospective analysis of 30 patients who received IMRT with weekly cisplatin-based medication. Corresponding 3DCRT plans were generated for comparison. Dosimetric parameters for Planning Target Volume (PTV) and Organs at Risk (OARs) were evaluated. Patients were immobilized in a supine position for simulation, according to conventional protocols.</p><p><strong>Results: </strong>PTV coverage was similar between IMRT and 3D-CRT groups. However, IMRT showed significantly improved dosimetric outcomes for OARs, including the bladder, rectum, bowel, and bone marrow. IMRT reduced doses to critical organs while maintaining comparable PTV coverage.</p><p><strong>Conclusion: </strong>Patients undergoing IMRT experienced reduced doses to critical organs compared to 3DCRT. Larger-scale trials with longer follow-up periods are needed to corroborate these findings and confirm IMRT's efficacy in cervical cancer treatments.</p>","PeriodicalId":53633,"journal":{"name":"The gulf journal of oncology","volume":"1 47","pages":"7-12"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparative Evaluation of Dosimetric Parameters in Carcinoma Cervix Patients Undergoing Intensity-Modulated Radiotherapy versus Three-Dimensional Radiotherapy: A Retrospective Analysis.\",\"authors\":\"Vishwadeep Mishra, Sudeep Bisht, Shwetima Chaudhary, Laxman Pandey, Archana Pandey, Rachita Chatterjee\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Cervical cancer affects many women across the globe and often requires radiation for treatment. This study aimed to compare the dosimetric outcomes of Intensity-Modulated Radiation Therapy (IMRT) and Three- Dimensional Conformal Radiation Therapy (3D-CRT) in managing locally advanced cervical carcinoma.</p><p><strong>Methods: </strong>We performed a retrospective analysis of 30 patients who received IMRT with weekly cisplatin-based medication. Corresponding 3DCRT plans were generated for comparison. Dosimetric parameters for Planning Target Volume (PTV) and Organs at Risk (OARs) were evaluated. Patients were immobilized in a supine position for simulation, according to conventional protocols.</p><p><strong>Results: </strong>PTV coverage was similar between IMRT and 3D-CRT groups. However, IMRT showed significantly improved dosimetric outcomes for OARs, including the bladder, rectum, bowel, and bone marrow. IMRT reduced doses to critical organs while maintaining comparable PTV coverage.</p><p><strong>Conclusion: </strong>Patients undergoing IMRT experienced reduced doses to critical organs compared to 3DCRT. Larger-scale trials with longer follow-up periods are needed to corroborate these findings and confirm IMRT's efficacy in cervical cancer treatments.</p>\",\"PeriodicalId\":53633,\"journal\":{\"name\":\"The gulf journal of oncology\",\"volume\":\"1 47\",\"pages\":\"7-12\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The gulf journal of oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The gulf journal of oncology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Comparative Evaluation of Dosimetric Parameters in Carcinoma Cervix Patients Undergoing Intensity-Modulated Radiotherapy versus Three-Dimensional Radiotherapy: A Retrospective Analysis.
Objective: Cervical cancer affects many women across the globe and often requires radiation for treatment. This study aimed to compare the dosimetric outcomes of Intensity-Modulated Radiation Therapy (IMRT) and Three- Dimensional Conformal Radiation Therapy (3D-CRT) in managing locally advanced cervical carcinoma.
Methods: We performed a retrospective analysis of 30 patients who received IMRT with weekly cisplatin-based medication. Corresponding 3DCRT plans were generated for comparison. Dosimetric parameters for Planning Target Volume (PTV) and Organs at Risk (OARs) were evaluated. Patients were immobilized in a supine position for simulation, according to conventional protocols.
Results: PTV coverage was similar between IMRT and 3D-CRT groups. However, IMRT showed significantly improved dosimetric outcomes for OARs, including the bladder, rectum, bowel, and bone marrow. IMRT reduced doses to critical organs while maintaining comparable PTV coverage.
Conclusion: Patients undergoing IMRT experienced reduced doses to critical organs compared to 3DCRT. Larger-scale trials with longer follow-up periods are needed to corroborate these findings and confirm IMRT's efficacy in cervical cancer treatments.
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