2009年至2020年美国1型糖尿病妊娠患者的糖尿病技术应用

IF 1.2 4区 医学 Q3 OBSTETRICS & GYNECOLOGY
Nasim C Sobhani, Yongmei Huang, Kartik K Venkatesh, Jason D Wright, Alexander M Friedman, Timothy Wen
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引用次数: 0

摘要

目的:连续血糖监测仪(CGM)和胰岛素泵的使用彻底改变了1型糖尿病(T1D)患者的护理。关于妊娠T1D人群使用糖尿病技术的数据很少。本研究旨在评估2009年至2020年美国妊娠TID患者糖尿病技术使用的时间趋势和预测因素。方法:使用2009年至2020年MarketScan®研究数据库,识别使用和未使用CGM和/或胰岛素泵的妊娠T1D患者。使用联结点回归分析来估计糖尿病技术使用随时间的平均年百分比变化(AAPC)。建立了未调整和调整的对数线性泊松回归模型,以评估CGM和胰岛素泵使用结果与人口统计学和临床预测因子之间的关系。以校正风险比(ARR)和95%置信区间(CI)报告相关关系。结果:在9201例妊娠T1D患者中,CGM的使用从2009年的2.3%增加到2020年的13.7% (AAPC为13.9%,95% CI为11.7-17.1%),而胰岛素泵的使用保持不变,从2009年的10.9%增加到2020年的11.8% (AAPC为-2.4%,95% CI为-4.4-0.4%)。医疗保险和肥胖与使用CGM和胰岛素泵的可能性较低相关,而高产科合并症指数评分与使用胰岛素泵的可能性较高相关(ARR 1.26, 95% CI 1.05-1.51)。结论:2009 - 2020年妊娠T1D患者使用CGM增加,而胰岛素泵使用不变。使用情况因患者人口统计学和临床因素而异,最值得注意的是使用CGM和使用医疗补助保险的胰岛素泵的可能性较低。尽管CGM的使用随着时间的推移而增加,但总体CGM的使用仍低于预期,尽管已知使用CGM可改善妊娠合并T1D的新生儿结局。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diabetes Technology Use in Pregnancies with Type 1 Diabetes in the United States from 2009 to 2020.

The use of continuous glucose monitors (CGM) and insulin pumps has revolutionized the care of patients with type 1 diabetes (T1D). Few data are available regarding the use of diabetes technology use in the pregnant T1D population. This study was conducted to evaluate temporal trends of diabetes technology use and predictors of use among pregnant individuals with TID in the United States from 2009 to 2020.MarketScan Research Databases from 2009 to 2020 were used to identify pregnant individuals with T1D who were and were not using CGM and/or insulin pumps. Joinpoint regression analysis was used to estimate the average annual percent change (AAPC) in diabetes technology use over time. Unadjusted and adjusted log-linear Poisson regression models were developed to assess the associations between the outcomes of CGM and insulin pump use and demographic and clinical predictors. Associations were reported as adjusted risk ratios (ARR) with 95% confidence intervals (CI).Among 9,201 pregnancies with T1D, CGM use increased from 2.3% in 2009 to 13.7% in 2020 (AAPC: 13.9%; 95% CI: 11.7-17.1), while insulin pump use remained unchanged from 10.9% in 2009 to 11.8% in 2020 (AAPC: -2.4%; 95% CI: -4.4 to 0.4). Medicaid insurance and obesity were associated with a lower likelihood of CGM use and insulin pump use, while a high obstetric comorbidity index score was associated with a higher likelihood of insulin pump use (ARR: 1.26; 95% CI: 1.05-1.51).From 2009 to 2020, CGM use among pregnant individuals with T1D increased, while insulin pump use remained unchanged. Use varied by patient demographic and clinical factors, most notable for lower likelihood of CGM use and insulin pump use with Medicaid insurance. Although CGM use increased over time, overall CGM use remained lower than expected despite the known benefits of CGM use in improving neonatal outcomes in pregnancies complicated by T1D. · CGM use in pregnant individuals with T1D increased from 2.3 to 13.7%, but pump use was stable.. · Medicaid and obesity were associated with lower CGM and pump use in pregnant individuals with T1D.. · Low CGM use in pregnant T1D individuals highlights barriers and the need for equitable access..

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来源期刊
American journal of perinatology
American journal of perinatology 医学-妇产科学
CiteScore
5.90
自引率
0.00%
发文量
302
审稿时长
4-8 weeks
期刊介绍: The American Journal of Perinatology is an international, peer-reviewed, and indexed journal publishing 14 issues a year dealing with original research and topical reviews. It is the definitive forum for specialists in obstetrics, neonatology, perinatology, and maternal/fetal medicine, with emphasis on bridging the different fields. The focus is primarily on clinical and translational research, clinical and technical advances in diagnosis, monitoring, and treatment as well as evidence-based reviews. Topics of interest include epidemiology, diagnosis, prevention, and management of maternal, fetal, and neonatal diseases. Manuscripts on new technology, NICU set-ups, and nursing topics are published to provide a broad survey of important issues in this field. All articles undergo rigorous peer review, with web-based submission, expedited turn-around, and availability of electronic publication. The American Journal of Perinatology is accompanied by AJP Reports - an Open Access journal for case reports in neonatology and maternal/fetal medicine.
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