后装载机集成的EMT使居住位置模型定义和质量保证在威尼斯妇科近距离治疗应用程序。

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Ioannis Androulakis, Myra van Laar, Jeremy Godart, Robin Straathof, Henrike Westerveld, Remi Nout, Mischa Hoogeman, Inger-Karine K Kolkman-Deurloo
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引用次数: 0

摘要

目的:在使用腔内涂布器近距离治疗妇科肿瘤时,通常使用涂布器库进行种植体重建。这些库包含涂抹器几何模型以及根据涂抹器几何定义的驻留位置(DP)模型。在本研究中,我们研究了后装载机集成电磁跟踪(EMT)系统是否可以用于此类应用程序的DP模型定义和质量保证。方法:使用后装机集成EMT系统测量四套Elekta Venezia Advanced ;两种配置的妇科涂药器(22 mm卵泡/40 mm宫腔和26 mm卵泡/70 mm宫腔)的居住位置。评估测量结果的可重复性,并与制造商指定的(MS) DP和计算机断层扫描(CT)校正的DP模型进行比较。 ;主要结果:EMT测量重现性良好,两种配置的测量值≤0.2 mm。两种配置的总体再现性,包括涂抹器几何再现性,均为 ;≤0.4 mm。观察到与制造商的DP模型存在显著差异,平均±sd偏差为1.13±0.66 mm(22/40)和1.37±0.63(26/70),特别是在宫内通道中,其中MS DP没有实验定义。当使用ct校正的DP模型作为基线时,差异减少到0.89±0.41 mm(22/40)和0.81±0.33 mm(26/70),突出了实验定义DP模型的必要性。单次测量的总体 ;不确定度低于临床可接受的2mm限值。意义:本研究证实了后装机集成EMT可以准确重建妇科近距离照射器的源 ;路径,并支持将其纳入临床 ;工作流程,提高质量保证和治疗精度。在宫内通道的临床相关部分,测量出与制造商DP模型的偏差,突出了EMT对质量保证的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Afterloader integrated EMT enables improved dwell position model definition and quality assurance in Venezia gynaecological brachytherapy applicators.

Objective.In brachytherapy for gynecological cancers using intracavitary applicators, implant reconstruction is commonly performed using applicator libraries. These libraries contain applicator geometry models as well as dwell position (DP) models defined in respect to the applicator geometry. In this study, we investigate whether an afterloader integrated electromagnetic tracking (EMT) system can be utilized for DP model definition and quality assurance in such applicators.Approach.DPs in four sets of two configurations of the Elekta Venezia Advanced Gynaecological Applicator (22 mm ovoids/40 mm intrauterine (IU) and 26 mm ovoids/70 mm IU) were measured using an afterloader integrated EMT system. Measurements were evaluated for reproducibility and compared against manufacturer-specified (MS) DPs and a computed tomography (CT)-corrected DP model.Main Results.Excellent EMT measurement reproducibility was observed, with values of ⩽0.2 mm for both configurations. The overall reproducibility, including applicator geometry reproducibility, was ⩽0.4 mm for both configurations. Significant discrepancies from the manufacturer's DP model were observed, with a mean ± sd deviation of 1.13 ± 0.66 mm (22/40) and 1.37 ± 0.63 (26/70), particularly in the IU channel, where MS DPs were not experimentally defined. Discrepancies were reduced to 0.89 ± 0.41 mm (22/40) and 0.81 ± 0.33 mm (26/70) when the CT-corrected DP model was used as baseline, highlighting the need for experimentally defined DP models. The overall uncertainty of single measurements was below the clinically acceptable 2 mm limit.Significance.This study confirms that afterloader integrated EMT can accurately reconstruct source paths in gynecological brachytherapy applicators and supports its incorporation into clinical workflows for improved quality assurance and treatment precision. The importance of EMT for quality assurance was highlighted by measured deviations from manufacturer's DP model in a clinical relevant part of the IU channel.

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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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