[胃癌腹膜转移个体化精准治疗进展]。

J H Zhao, Y Q Yang, R Ma, C Z Zhang, Z C Hong, Z N Wang
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引用次数: 0

摘要

腹膜转移是胃癌最具侵袭性的转移形式,也是导致预后不良的主要原因。传统的治疗方法提供有限的生存效益,使新的治疗策略的发展成为迫切的医疗优先事项。随着分子医学和社会医学的进步,当代癌症管理正朝着个性化的精准医疗发展。这种转变产生了大量的创新治疗策略,包括分子分型驱动的靶向治疗、免疫治疗和局部靶向技术。这些策略强调通过基因组学、影像基因组学和人工智能辅助决策的整合,构建精准、个体化的治疗框架,促进胃癌腹膜转移治疗策略的不断完善。本文从精准医学的角度全面分析了目前流行的个体化治疗方式,为胃癌腹膜转移的治疗提供了新的视角。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Progress of individualized precision therapy for peritoneal metastasis in gastric cancer].

Peritoneal metastasis represents the most aggressive form of gastric cancer metastasis and serves as a primary contributor to poor prognosis. Conventional therapeutic approaches offer limited survival benefits, making the development of novel treatment strategies an urgent medical priority. With advancements in molecular medicine and sociomedical sciences, contemporary cancer management is evolving towards individualized precision medicine. This transition has given rise to a plethora of innovative therapeutic strategies, including molecular typing-driven targeted therapy, immunotherapy, and locally targeted technology. These strategies emphasize the construction of a precise and individualized therapeutic framework through the integration of genomics, imaging genomics, and artificial intelligence-assisted decision-making, which promotes the continuous improvement of treatment strategies for peritoneal metastasis of gastric cancer. This article provides a comprehensive analysis of the prevailing individualized treatment modalities from the standpoint of precision medicine, offering novel perspectives on the management of peritoneal metastasis in gastric cancer.

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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
20861
期刊介绍: Chinese Journal of Surgery|Chin J Surg (monthly) is a high-level medical science and technology journal approved by the General Administration of Press and Publication of the People's Republic of China, under the supervision of the China Association for Science and Technology, and organised by the Chinese Medical Association for domestic and international public circulation. It was founded in January 1951, and is published on the basis of the Journal of Chinese Surgery. The Journal is aimed at senior and intermediate surgeons and related researchers, mainly reporting the leading scientific research results and clinical experience in the field of surgery, as well as the basic theoretical research that has a guiding effect on the clinical work of surgery. Chinese Journal of Surgery|Chin J Surg is committed to reflecting the major research progress in the field of surgery in China and promoting academic exchanges at home and abroad. The main columns include thesis, meta-analysis, review, expert forum, synthesis, case report, diagnosis and treatment experience, technical exchange, clinical case discussion, academic controversy, and special lectures, etc. The journal has been accepted by the National Academy of Medicine of the United States. The journal has been included in many famous databases at home and abroad, such as the Biomedical Analysis and Online Retrieval System (MEDLINE) of the U.S. National Library of Medicine.
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